Human-specific mutations in VMAT1 confer functional changes and multi-directional evolution in the regulation of monoamine circuits

Autor: Daiki X. Sato, Yuu Ishii, Tomoaki Nagai, Kazumasa Ohashi, Masakado Kawata

Publikováno v: BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-10 (2019)

Abstract Background Neurochemicals like serotonin and dopamine play crucial roles in human cognitive and emotional functions. Vesicular monoamine transporter 1 (VMAT1) transports monoamine neurotransmitters, and its variant (136Thr) is associated wit

Externí odkaz: https://doaj.org/article/b1522340e2e7444497e69fde2a3a6907

Phenotypical and Myopathological Consequences of Compound Heterozygous Missense and Nonsense Variants in SLC18A3

Autor: Della Marina, Adela, Arlt, Annabelle, Weis, Joachim, Czech, Artur, Grüneboom, Anika, Roos, Andreas, Schara-Schmidt, Ulrike, Depienne, Christel, Gangfuß, Andrea, Kölbel, Heike, Sickmann, Albert, Freier, Erik, Kohlschmidt, Nicolai, Hentschel, Andreas

Publikováno v: Cells, Vol 10, Iss 3481, p 3481 (2021)
Cells : open access journal 10(12), 3481 (2021). doi:10.3390/cells10123481 special issue: "Special Issue "Cellular and Molecular Mechanisms in Neuromuscular Diseases: From Basic Research to Clinical Approach" / Special Issue Editors: Dr. Anne Schänzer, Guest Editor; Dr. Tobias Ruck, Guest Editor; Prof. Dr. Andreas Hahn, Guest Editor; Dr. Corinna Preusse, Guest Editor"

Cells : open access journal 10(12), 3481 (2021). doi:10.3390/cells10123481 special issue: "Special Issue "Cellular and Molecular Mechanisms in Neuromuscular Diseases: From Basic Research to Clinical Approach" / Special Issue Editors: Dr. Anne Schänz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193dc9d1ab8a2cda2eed8aa9c00d859d
https://duepublico2.uni-due.de/receive/duepublico_mods_00076367

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Dysmorphic contribution of neurotransmitter and neuroendocrine system polymorphisms to subtherapeutic mood states

Autor: Jose Luis Royo, Armando Reyes-Engel, Rocio Polvillo, Maximiliano Ruiz-Galdón, Irene Gonzalez

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Brain and Behavior

© The Author(s).
[Objective]: From an evolutionary perspective, emotions emerged as rapid adaptive reactions that increase survival rates. Current psychobiology includes the consideration that genetic changes affecting neuroendocrine and neurot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce61aee060f955632f9c7b554d51a69
http://hdl.handle.net/10261/202200

Dopamine gene methylation patterns are associated with obesity markers and carbohydrate intake

Autor: Ramos-López, O. (Omar), Riezu-Boj, J.I. (José Ignacio), Milagro, F.I. (Fermín I.), Martinez, J.A. (José Alfredo)

Introduction: Dopamine (DA) is a neurotransmitter that regulates the rewarding and motivational processes underlying food intake and eating behaviors. This study hy-pothesized associations of DNA methylation signatures at genes modulating DA sign -al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1111::25580fc42871f2b8d6a0cb693e31f37f
https://hdl.handle.net/10171/64945