Zobrazeno 1 - 10
of 133
pro vyhledávání: '"SLC10A2"'
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 9, Iss 8, Pp n/a-n/a (2021)
Abstract Background Diarrhea is a common occurrence in children below the age of 5 years. In chronic cases, it induces malnutrition that severely stunts growth. Bile acid diarrhea (BAD), caused by malabsorption of bile acid (BA), is a rare form of ch
Externí odkaz:
https://doaj.org/article/3705429a9a794557a19d11887bdf74ef
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Three carriers of the solute carrier family SLC10 have been functionally characterized so far. Na+/taurocholate cotransporting polypeptide NTCP is a hepatic bile acid transporter and the cellular entry receptor for the hepatitis B and D viruses. Its
Externí odkaz:
https://doaj.org/article/50f697095c324c88874be5f26e09cb45
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Thirty to 40 % of non-small cell lung cancer (NSCLC) patients developed higher hypertriglyceridemia in the process of treatment with bexarotene. And bioinformatics studies discovered that the expression of slc10a2 was increased in
Externí odkaz:
https://doaj.org/article/0a334ee32f4c470f99ca55287c4b7484
Publikováno v:
Journal of Pharmaceutical Sciences. 110:1392-1400
This study aimed to demonstrate usefulness of the fluorophore-labeled bile acid derivative, N-(24-[7-(4-N,N-dimethylaminosulfonyl-2,1,3-benzoxadiazole)]amino-3α,7α,12α-trihydroxy-27-nor-5β-cholestan-26-oyl)-2′-aminoethane sulfonate (tauro-nor-T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2401be118d077adf9b7a35453da3d5f7
https://doi.org/10.1016/j.xphs.2020.11.030
https://doi.org/10.1016/j.xphs.2020.11.030
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 973-997 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The functions of the liver and the intestine are closely tied in both physiological and pathologic conditions. The gut microbiota (GM) often cause deleterious effects during hepatic pathogenesis. Autophagy is essential for liver hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5847c5c25a4c55b7146f469ae9e2e369
http://www.sciencedirect.com/science/article/pii/S2352345X20301740
http://www.sciencedirect.com/science/article/pii/S2352345X20301740
Autor:
Waddah A. Alrefai, Pooja Malhotra, Alexander L. Ticho, Christopher R. Manzella, Seema Saksena, Pradeep K. Dudeja, Ravinder K. Gill
Publikováno v:
J Biol Chem
The ileal apical sodium-dependent bile acid transporter (ASBT) is crucial for the enterohepatic circulation of bile acids. ASBT function is rapidly regulated by several posttranslational modifications. One reversible posttranslational modification is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb387e949ba6237072a6ba2cca2c55c6
https://doi.org/10.1074/jbc.ra119.011032
https://doi.org/10.1074/jbc.ra119.011032
Autor:
Xiaohu Wang, Xueshan Zhao, Yichao Geng, Shuangwu Feng, Lina Wang, Xiaoming Hou, Yan Zhou, Qiuning Zhang, Bin Guo, Juntao Ran, Chengcheng Li, Guangwen Zhang
Publikováno v:
International Journal of Radiation Biology. 96:510-519
Background: Radiation is a mode of treatment for many pelvic malignancies, most of which originate in the gynecologic, gastrointestinal, and genitourinary systems. However, the healthy gut is unavo...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fc3394a6def6205e98b4c4b0d34f328
https://doi.org/10.1080/09553002.2020.1707324
https://doi.org/10.1080/09553002.2020.1707324
Autor:
Huijuan Wu, Changyuan Yang, Zili Lei, Xueying Zhang, Fengxue Tong, Yuting Lei, Ya Nie, Wanwan Liu, Lanxiang Yang, Ting Lin, Jiao Guo, Qing Hu, Yanhong Yang, Jiamin Zhu
Publikováno v:
Bioorganicmedicinal chemistry. 53
The increase of concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) in the serum of postmenopausal women is the important risk factor of the high morbidity of cardiovascular diseases of old women worldwide. To tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f9cb517f5b0a028048fa78196957f2
https://pubmed.ncbi.nlm.nih.gov/34847494
https://pubmed.ncbi.nlm.nih.gov/34847494
Autor:
Theo H. van Dijk, Anna Bertolini, Albert K. Groen, Henkjan J. Verkade, Johan W. Jonker, Ivo P van de Peppel
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 9, Pp 1562-1572 (2019)
Journal of Lipid Research, 60(9), 1562-1572. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Journal of lipid research, 60(9), 1562-1572. American Society for Biochemistry and Molecular Biology Inc.
J Lipid Res
Journal of Lipid Research, 60(9), 1562-1572. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Journal of lipid research, 60(9), 1562-1572. American Society for Biochemistry and Molecular Biology Inc.
J Lipid Res
Transintestinal cholesterol excretion (TICE) is a major route for eliminating cholesterol from the body and a potential therapeutic target for hypercholesterolemia. The underlying mechanism, however, is largely unclear, and its contribution to choles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734da4eecc9690a38ef9c96adccdea15
http://www.sciencedirect.com/science/article/pii/S002222752032318X
http://www.sciencedirect.com/science/article/pii/S002222752032318X
Publikováno v:
Molecular Pharmaceutics. 16:3569-3576
The human apical sodium-dependent bile acid transporter (hASBT; SLC10A2) is responsible for the reclamation of bile acids from the intestinal lumen, providing a primary mechanism for bile acid and cholesterol homeostasis. However, the regulation of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b3a5efb40987b310aa9b7741abf4e3e
https://doi.org/10.1021/acs.molpharmaceut.9b00426
https://doi.org/10.1021/acs.molpharmaceut.9b00426