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P4-09-04: Do Decreased CEP17 Signals Indicate the Presence of 'Monosomy' in Breast Cancer? A Study of HER2 Gene Status and HER2 Immunohistochemistry

Autor: Allen M. Gown, Harry C. Hwang, SM Duesterhoeft, SL Kussick, LC Goldstein, CH Tse, PL Kandalaft

Publikováno v: Cancer Research. 71:P4-09

Background: Detection of HER2 gene amplification by fluorescence in-situ hybridization (FISH) is one of the key tests predicting clinical response of breast cancer to trastuzumab. According to the recent ASCO/CAP guidelines for HER2 testing, the tumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc9dff4547f3e40eaea66474526b6821
https://doi.org/10.1158/0008-5472.sabcs11-p4-09-04

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Amplification involving the CEP17 region may lead to false negative results of HER2 gene amplification by FISH

Autor: Geoffrey S. Baird, LC Goldstein, Allen M. Gown, TS Barry, SL Kussick, PL Kandalaft, CH Tse

Publikováno v: Cancer Research. 69:1079

Abstract #1079 Background: Detection of HER2 gene amplification by fluorescence in-situ hybridization (FISH) is one of the key tests predicting clinical response of breast cancer to trastuzumab. According to the recent CAP/ASCO guidelines for HER2 te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b223f7e658c0b76d32a710fd3c8424c4
https://doi.org/10.1158/0008-5472.sabcs-1079

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