Zobrazeno 1 - 10
of 2 443
pro vyhledávání: '"SKP2"'
Autor:
Marwa Elfoly, Jumanah Y. Mirza, Ayodele Alaiya, Amal A. Al-Hazzani, Asma Tulbah, Monther Al-Alwan, Hazem Ghebeh
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background PD-L1 intrinsically promotes tumor progression through multiple mechanisms, which potentially leads to resistance to anti-PD-1/PD-L1 therapies. The intrinsic effect of PD-L1 on breast cancer (BC) cell proliferation has not been fu
Externí odkaz:
https://doaj.org/article/f566893f991f499ea6cf467f7bb0d987
Autor:
Jinlian Liu, Ke Song, Bingqi Lin, Zhenfeng Chen, Yan Liu, Xianshuai Qiu, Qi He, Zirui Zuo, Xiaodan Yao, Xiaoxia Huang, Zhuanhua Liu, Zhifeng Liu, Qiaobing Huang, Xiaohua Guo
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Background Acute lung injury (ALI) is strongly associated with hospitalization and mortality in patients with sepsis. Recent evidence suggests that pyroptosis mediated by NLRP3(NOD-, LRR- and pyrin domain-containing 3) inflammasome activatio
Externí odkaz:
https://doaj.org/article/3a81b8937f8a48ef84f63b8a8e08f854
Akademický článek
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Autor:
Jonahunnatha Nesson George William, Ruby Dhar, Rohit Gundamaraju, Om Saswat Sahoo, Karthikeyan Pethusamy, A. F. P. Allwin Mabes Raj, Subbiah Ramasamy, Mohammed S. Alqahtani, Mohamed Abbas, Subhradip Karmakar
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
SKP2 (S-phase kinase-associated protein 2) is a member of the F-box family of substrate-recognition subunits in the SCF ubiquitin-protein ligase complexes. It is associated with ubiquitin-mediated degradation in the mammalian cell cycle components an
Externí odkaz:
https://doaj.org/article/f80356813a394a99b38c7301007bbe26
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Background Antiepileptic drugs (AEDs) harm bone health and are significantly associated with osteoporosis development. In this study, we aimed to explore the mechanisms involved in carbamazepine (CBZ) and microRNA (miR)-20a-5p/ubiquitin-spec
Externí odkaz:
https://doaj.org/article/02a4ec5ec32a4431a35020d094051fb6
Autor:
Sherly I. Celada, Guoliang Li, Lindsay J. Celada, Wenfu Lu, Thanigaivelan Kanagasabai, Weiran Feng, Zhen Cao, Nazifa Salsabeel, Ninghui Mao, LaKendria K. Brown, Zaniya A. Mark, Michael G. Izban, Billy R. Ballard, Xinchun Zhou, Samuel E. Adunyah, Robert J. Matusik, Xiaofei Wang, Zhenbang Chen
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2126-2146 (2023)
Changes in FOXA1 (forkhead box protein A1) protein levels are well associated with prostate cancer (PCa) progression. Unfortunately, direct targeting of FOXA1 in progressive PCa remains challenging due to variations in FOXA1 protein levels, increased
Externí odkaz:
https://doaj.org/article/0cac8103e1024d5d960e34525c1fc17d
Autor:
Yi Shen, Jun Li, Dan Peng, Lele Liao, Xia Chen, Weiye Zhong, Zicheng Liu, Chao Yu, Yuanliang Sun
Publikováno v:
Genes and Diseases, Vol 10, Iss 5, Pp 2125-2136 (2023)
Osteosarcoma is a common malignant tumor occurring in children and young adults. Chondroitin sulfate (CS) participates in cell adhesion, cell division, and the formation of neural networks in the body, the biosynthesis of which requires the participa
Externí odkaz:
https://doaj.org/article/ba3262cc2d2a4f06995815847fa0d9e3
Akademický článek
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Autor:
Antonio Cigliano, Maria M. Simile, Gianpaolo Vidili, Giovanni M. Pes, Maria P. Dore, Francesco Urigo, Eleonora Cossu, Li Che, Claudio Feo, Sara M. Steinmann, Silvia Ribback, Rosa M. Pascale, Matthias Evert, Xin Chen, Diego F. Calvisi
Publikováno v:
Medicina, Vol 60, Iss 7, p 1160 (2024)
Background and Objectives: Aberrant upregulation of fatty acid synthase (FASN), catalyzing de novo synthesis of fatty acids, occurs in various tumor types, including human hepatocellular carcinoma (HCC). Although FASN oncogenic activity seems to resi
Externí odkaz:
https://doaj.org/article/9b831399f08b4b718d5859120af5fc63
Akademický článek
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