Overlapping BXSB congenic intervals, in combination with microarray gene expression, reveal novel lupus candidate genes

Autor: Bernard J Morley, SJ Rose, Stuart Horswell, G Fu, Mark Walport, Michelle E. K. Haywood, MJ Lees

Publikováno v: Genes & Immunity. 7:250-263

The BXSB mouse strain is an important model of glomerulonephritis observed in systemic lupus erythematosus (SLE). Linkage studies have successfully identified disease-susceptibility intervals; however, extracting the identity of the susceptibility ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177d56daccb3e8f76e2ed0a6d1365241
https://doi.org/10.1038/sj.gene.6364294

Identification of intervals on chromosomes 1, 3, and 13 linked to the development of lupus in BXSB mice

Autor: Elizabeth Simpson, SJ Rose, MA Maibaum, Michelle E. K. Haywood, MB Hogarth, Kevin A. Davies, Phillip Chandler, PJ Allen, Mark Walport, JH Slingsby, Bernard J Morley, EM Thompson

Publikováno v: Arthritis and rheumatism. 43(2)

Objective To identify intervals containing systemic lupus erythematosus (SLE) susceptibility alleles in the BXSB strain of mice. Methods We analyzed 286 (B10 × [B10 × BXSB]F1) backcross mice for a range of phenotypic traits associated with the deve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdc715796613887d0976c7811fb37b2
https://pubmed.ncbi.nlm.nih.gov/10693874

Erythrocyte Cdp-Choline Accumulation in Haemolytic Anaemia and Renal Failure (Rf)

Autor: H. A. Simmonds, Susan J. Kelly, M. Layton, SJ Rose, John A. Duley, Arian Laurence

Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9781461374565

The accumulation of CDP-choline in high concentrations in the erythrocytes of a patient with haemolytic anaemia was first reported by Paglia et al. (1). A defect in CDP-choline phosphotransferase was suggested (Fig. 1). The selective nucleotide accum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d000a17c02b8c6e53124833b117ebbbb
https://doi.org/10.1007/978-1-4615-5381-6_30

Regulation of transcription of the TATA-less human complement component C4 gene

Autor: Ak, Vaishnaw, Tj, Mitchell, Sj, Rose, Mark Walport, Bj, Morley

Publikováno v: Europe PubMed Central

The 5'-sequences flanking the human complement component C4 genes (C4A and C4B) have been analyzed for their ability to direct expression of a reporter gene in cell lines that constitutively express or do not express C4. No difference in the level of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::588e711a961a729acdaaa4210f74f8d2
http://europepmc.org/abstract/med/9574539

Myocarditis and pericarditis in young patients following Campylobacter jejuni enterocolitis infection: a systematic review of case studies.

Autor: Sanicola K; Masters of Science in Physician Assistant Studies, Sacred Heart University, 551 Park Avenue, Fairfield, CT, 06825, USA., Shadani N; Masters of Science in Physician Assistant Studies, Sacred Heart University, 551 Park Avenue, Fairfield, CT, 06825, USA., Nemec EC 2nd; Masters of Science in Physician Assistant Studies, Sacred Heart University, 551 Park Avenue, Fairfield, CT, 06825, USA., Rose SJ; Masters of Science in Physician Assistant Studies, Sacred Heart University, 551 Park Avenue, Fairfield, CT, 06825, USA. srose@stamhealth.org.; Department of Research and Discovery, Stamford Health, One Hospital Plaza, PO Box 9317, Stamford, CT, 06902, USA. srose@stamhealth.org.

Publikováno v: Journal of medical case reports [J Med Case Rep] 2024 Nov 22; Vol. 18 (1), pp. 566. Date of Electronic Publication: 2024 Nov 22.