Zobrazeno 1 - 10
of 40
pro vyhledávání: '"SIV, simian immunodeficiency virus"'
Autor:
Meredith E. Davis-Gardner, Jesse A. Weber, Jun Xie, Katja Pekrun, Eric A. Alexander, Kim L. Weisgrau, Jessica R. Furlott, Eva G. Rakasz, Mark A. Kay, Guangping Gao, Michael Farzan, Matthew R. Gardner
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionUse of adeno-associated virus (AAV) vectors is complicated by host immune responses that can limit transgene expression. Recent clinical trials using AAV vectors to deliver HIV broadly neutralizing antibodies (bNAbs) by intramuscular admi
Externí odkaz:
https://doaj.org/article/00463782da80486d88a3fbab8e5a811b
Autor:
Samuel Long
Publikováno v:
Methods (San Diego, Calif.)
Sensitive PCR detection of viral nucleic acids plays a critical role in infectious disease research, diagnosis and monitoring. In the context of SARS-CoV-2 detection, recent reports indicate that digital PCR-based tests are significantly more sensiti
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Adipose tissue comprises one of the largest organs in the body and performs diverse functions including energy storage and release, regulation of appetite and other neuroendocrine signaling, and modulation of immuity, among others. Adipocytes reside
Externí odkaz:
https://doaj.org/article/a71ffcd2df904307977127ba7a11bd89
Akademický článek
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Autor:
Yong Xiong, Fidel Arizaga, Adrian Oo, Nicole E. Bowen, Caitlin Shepard, Baek Kim, David S. Yu, Joshua Temple, Corey H. Yu, Dmitri N. Ivanov, Felipe Diaz-Griffero, Dong-Hyun Kim, Mirjana Persaud, Priya Kapoor-Vazirani, Raymond F. Schinazi
Publikováno v:
The Journal of Biological Chemistry
Elevated intracellular levels of dNTPs have been shown to be a biochemical marker of cancer cells. Recently, a series of mutations in the multifunctional dNTP triphosphohydrolase (dNTPase), sterile alpha motif and histidine–aspartate domain–conta
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1701-1718 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1701-1718 (2021)
Intestinal macrophages play a key role in the gut immune system and the regulation of gastrointestinal physiology, including gut motility and secretion. Their ability to keep the gut from chronic inflammation despite constantly facing foreign antigen
Autor:
Shervin Shokouhi, Atieh Pourbagheri-Sigaroodi, Mahda Delshad, Behzad Poopak, Davood Bashash, Ava Safaroghli-Azar
Publikováno v:
International Immunopharmacology
Graphical abstract
Despite endorsed and exponential research to improve diagnostic and therapeutic strategies, efforts have not yet converted into a better prospect for patients infected with the novel coronavirus (2019nCoV), and still, the name
Despite endorsed and exponential research to improve diagnostic and therapeutic strategies, efforts have not yet converted into a better prospect for patients infected with the novel coronavirus (2019nCoV), and still, the name
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 5, Iss 6, Pp 493-499 (2015)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Despite significant advances in antiretroviral therapy, increasing drug resistance and toxicities observed among many of the current approved human immunodeficiency virus (HIV) drugs indicate a need for discovery and development of potent and safe an
Autor:
Eliana M. Coccia, Angela Battistini
Publikováno v:
Seminars in Immunology
Highlights • Type I interferon represents the first line of innate host defense against a number of invading pathogens that also instructs adaptive immunity. • Type I interferon induction downstream germ-line-encoded pattern recognition receptors
Autor:
Andreas Wagner, Marc G. Aucoin, Jonas M.S. Andrich, Steve George, Anup Tuladhar, Stanislav Sokolenko
Publikováno v:
Biotechnology Advances
The baculovirus expression vector system (BEVS) is a versatile and powerful platform for protein expression in insect cells. With the ability to approach similar post-translational modifications as in mammalian cells, the BEVS offers a number of adva