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PP2A-Like Protein Phosphatase (Sit4) Regulatory Subunits, Sap155 and Sap190, Regulate Candida albicans’ Cell Growth, Morphogenesis, and Virulence

Autor: Qi Han, Chaoying Pan, Yueqing Wang, Linpeng Zhao, Yue Wang, Jianli Sang

Publikováno v: Frontiers in Microbiology, Vol 10 (2019)

PP2A-like phosphatases share high homology with PP2A enzymes and are composed of a catalytic subunit and a regulatory subunit. In Candida albicans, the PP2A-like catalytic subunit SIT4 regulates cell growth, morphogenesis, and virulence. However, the

Externí odkaz: https://doaj.org/article/1e04bbc5e39d45f0a18eecc8018c59bf

Protein Phosphatase Sit4 Affects Lipid Droplet Synthesis and Soraphen A Resistance Independent of Its Role in Regulating Elongator Dependent tRNA Modification

Autor: Bruno Leonardo Bozaquel-Morais, Leonie Vogt, Valentina D’Angelo, Raffael Schaffrath, Roland Klassen, Mónica Montero-Lomelí

Publikováno v: Biomolecules, Vol 8, Iss 3, p 49 (2018)

The protein phosphatase Sit4 has been shown to be required for lipogenesis and resistance against the acetyl-CoA carboxylase inhibitor soraphen A. Since Sit4 is also required for biosynthesis of Elongator dependent tRNA modifications such as 5-methox

Externí odkaz: https://doaj.org/article/13b57e4a55c642baa2db95a833a248c0

Sphingolipids and Inositol Phosphates Regulate the Tau Protein Phosphorylation Status in Humanized Yeast

Autor: Maurizio Del Poeta, Lino Bojunga, Joris Winderickx, Jose Antonio Prieto, Francisca Randez-Gil, Francisco Estruch

Publikováno v: Frontiers in Cell and Developmental Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Rández-Gil, Francisca Bojunga, Lino Estruch Ros, Francisco Winderickx, Joris Del Poeta, Maurizio Prieto Alamán, José Antonio 2020 Sphingolipids and inositol phosphates regulate the tau protein phosphorylation status in humanized yeast Frontiers In Cell And Developmental Biology 8 592159
RODERIC. Repositorio Institucional de la Universitat de Valéncia
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
RODERIC: Repositorio Institucional de la Universitat de Valéncia

Hyperphosphorylation of protein tau is a hallmark of Alzheimer’s disease (AD). Changes in energy and lipid metabolism have been correlated with the late onset of this neurological disorder. However, it is uncertain if metabolic dysregulation is a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec566d2308a05843bf235d2ae80525e
http://europepmc.org/articles/PMC7705114

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