Zobrazeno 1 - 10
of 705
pro vyhledávání: '"SIRT7"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Long noncoding RNAs (lncRNAs) play vital regulatory functions in non-small cell lung cancer (NSCLC). Cisplatin (DDP) resistance has significantly decreased the effectiveness of DDP-based chemotherapy in NSCLC patients. This study
Externí odkaz:
https://doaj.org/article/543cf20db79a402ca36954aebf128cee
Publikováno v:
Clinical, Cosmetic and Investigational Dermatology, Vol Volume 17, Pp 1495-1504 (2024)
Yuehong Ma, Hongqin Chang Department of Dermatology, The Affiliated Changzhou Second People’s Hospital of Nanjing Medical University, Changzhou, People’s Republic of ChinaCorrespondence: Hongqin Chang, Department of Dermatology, The Affiliated Ch
Externí odkaz:
https://doaj.org/article/9903f38b57bc472e9bf8f37bb3e6446e
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 2655-2671 (2024)
Chuang Qin,1 Xiaofei Ye,1 Hongliang Luo,1 Hu Jin,1 Qiang Liu,1 Jiangfa Li2 1Hepatobiliary Surgery, Liuzhou People’s Hospital Affiliated to Guangxi Medical University, Liuzhou City, Guangxi, People’s Republic of China; 2Hepatobiliary Surgery, The
Externí odkaz:
https://doaj.org/article/24a31996851c406c8672ed979afd0807
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 8, Pp n/a-n/a (2024)
Abstract Background Sirtuin 7 (SIRT7) is pivotal in diverse diseases progression. Importantly, SIRT7 is associated with melanin production. However, whether SIRT7 regulates vitiligo is unclear. Therefore, we aimed to investigate the effects of SIRT7
Externí odkaz:
https://doaj.org/article/f8e7e719a121458996a31bb9e659f8b1
Autor:
Wu Mengchen, Hao Yingxiang, Wu Xinwan, Zhu Minmin, Chen Xiangyuan, Qi Jie, Yu Zhuang, Xu Hongjiao
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 586-596 (2024)
Diabetic nephropathy (DN) is the main cause of end-stage renal disease worldwide. It is reported that the endothelial-to-mesenchymal transition (EndMT) in glomerular endothelial cells plays an important role in DN. As a specific form of epithelial-to
Externí odkaz:
https://doaj.org/article/5cec4e563d854713874aee6b0920ed4b
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Objective This study was designed to investigate the regulatory effects of kinesin family member (KIF) 23 on anaplastic thyroid cancer (ATC) cell viability and migration and the underlying mechanism. Methods Reverse transcription-quantitativ
Externí odkaz:
https://doaj.org/article/7ae6ea1058f04b218a8bbfa62431066c
Publikováno v:
Molecular & Cellular Oncology, Vol 11, Iss 1 (2024)
The nucleolar enzyme sirtuin 7 (SIRT7) promotes cancer progression in certain malignancies, likely in part by controlling ribosome biosynthesis. Recently, we discovered that SIRT7 destabilizes the cyclin dependent kinase inhibitor 2A (CDKN2A, known a
Externí odkaz:
https://doaj.org/article/03eb20f5ed864562b688aaa4bafe46f1
Autor:
Liangjie Sun, Yi Li, Meng Wang, Lan Luo, Ruiqing Sun, Yang Chen, Yan Bai, Chong Ding, Yixiang Wang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
p53 deficiency plays a crucial role in chemotherapy resistance through various biological events, including posttranslational modifications (PTMs). Recently, lysine crotonylation (Kcr) has been shown to play a vital role in cancer progression. Howeve
Externí odkaz:
https://doaj.org/article/20232494038f40bd8dd5d272cfeacb96
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Sirtuin 7 (SIRT7) is an oncogene that promotes tumor progression in various malignancies, however, its role and regulatory mechanism in cervical squamous cell carcinoma (CSCC) is unknown. Herein, we attempted to investigate the fu
Externí odkaz:
https://doaj.org/article/bf42f8fb3e2f4deb8381dc84185c44c1
Autor:
Berta N. Vazquez, Irene Fernández-Duran, Yurdiana Hernandez, Shahriar Tarighi, Joshua K. Thackray, Maria Espinosa-Alcantud, Poonam Kumari, Alessandro Ianni, Lionel Cesaire, Thomas Braun, Manel Esteller, Jay Tischfield, Alejandro Vaquero, Lourdes Serrano
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
p53 is a hallmark tumor suppressor due in part to its role in cell cycle progression, DNA damage repair, and cellular apoptosis; its protein activity interrelates with the Sirtuin family of proteins, major regulators of the cellular response to metab
Externí odkaz:
https://doaj.org/article/1c3e85eb7aee42cd830d2e05171e732e