Zobrazeno 1 - 10
of 5 391
pro vyhledávání: '"SIRT3"'
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 7675-7685 (2024)
Nan Gao,1,2 Xiao-Yu Liu,1,2 Jie Chen,1,2 Tian-Peng Hu,1,2 Yu Wang,2,3 Guo-Qiang Zhang2 1China-Japan Friendship Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; 2Department of Emerg
Externí odkaz:
https://doaj.org/article/4129615a14664c0680dfaace5bd7a233
Autor:
Liqing Jiang, Linhe Lu, Chao Xue, He Sun, Kai Ren, Liyun Zhang, Hanzhao Zhu, Bin Zhang, Xiaoya Wang, Xinan Qiao, Xiangyan Peng, Jincheng Liu, Weixun Duan
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-16 (2024)
Abstract Background Thoracic aortic dissection (TAD) is an irreversible cardiovascular disorder with high mortality and morbidity. However, the molecular mechanisms remain elusive. Thus, identifying an effective therapeutic target to prevent TAD is e
Externí odkaz:
https://doaj.org/article/2a03e87d8c944a6cbcf280f8c75aadc1
Autor:
Youhong Luo, Tongtong Ye, Hongzhan Tian, Hongwei Song, Chengxia Kan, Fang Han, Ningning Hou, Xiaodong Sun, Jingwen Zhang
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Empagliflozin (EMPA) has demonstrated efficacy in providing cardiovascular benefits in metabolic diseases. However, the direct effect of EMPA on autophagy in obesity-related cardiac dysfunction remains unclear. Therefore, this stu
Externí odkaz:
https://doaj.org/article/e0cadb9879a640cda135d266c3df6b0b
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background The established association between Alzheimer's disease (AD) and compromised neural regeneration is well-documented. In addition to the mitigation of apoptosis in neural stem cells (NSCs), the induction of neurogenesis has been pr
Externí odkaz:
https://doaj.org/article/509fe601a6e7470b9ea8a790c186aa8e
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Myocardial ischemia-reperfusion injury (MIRI) is a significant complication following reperfusion therapy after myocardial infarction. Mitochondrial oxidative stress is a critical factor in MIRI, and Sirtuin 3 (SIRT3), as a major mitochondri
Externí odkaz:
https://doaj.org/article/aec63f5bf9f248e79ebe2aab73bd0c90
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Activation of the NLRP3 inflammasome is critical in the inflammatory response to gout. Potassium ion (K+) efflux mediated by the TWIK2 channel is an important upstream mechanism for NLRP3 inflammasome activation. Therefore, the TW
Externí odkaz:
https://doaj.org/article/81865ab612744afb8397769e76bd6588
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 7, Pp 850-856 (2024)
Objective(s): To investigate the protective effect of N-acetylcysteine (NAC) on septic acute kidney injury (SAKI) via regulating Sirtuin3 (SIRT3)-mediated mitochondrial dysfunction and apoptosis.Materials and Methods: By constructing SIRT3 knockout m
Externí odkaz:
https://doaj.org/article/7c2b177e84bf4ce89796f9822404afc6
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 837-47 (2024)
In this prospective observational study, we aimed to investigate the serum levels of sirtuin (SIRT)3 in epilepsy patients and its association with the severity of the disease.
Externí odkaz:
https://doaj.org/article/83bd7efa02d44fbd83b0bf3fd3b3347d
Publikováno v:
Zhongguo aizheng zazhi, Vol 34, Iss 6, Pp 537-547 (2024)
Background and purpose: Silent information regulator proteins (sirtuins, SIRT) are a class Ⅲ histone deacetylases with nicotinamide adenine dinucleotide (NAD+) as coenzyme. YME1 like 1 ATPase (YME1L1) is essential for the maintenance of mitochondri
Externí odkaz:
https://doaj.org/article/1f3307745bd349eebb666dad2693413b
Publikováno v:
Cell Division, Vol 19, Iss 1, Pp 1-8 (2024)
Abstract The silencing regulatory factor 2-like protein 3 (SIRT3) is a nicotinamide adenine dinucleotide (NAD+) dependent deacetylase located primarily in the mitochondria. This protein plays an important role in oxidative stress, energy metabolism,
Externí odkaz:
https://doaj.org/article/66d23cd1b2574c29a0706a8e354fd423