Zobrazeno 1 - 10 of 5 384 pro vyhledávání: '"SIRT1, sirtuin 1"'
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Akademický článek
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3
Energy sensors and reproductive hypothalamo-pituitary ovarian axis (HPO) in female mammals: Role of mTOR (mammalian target of rapamycin), AMPK (AMP-activated protein kinase) and SIRT1 (Sirtuin 1)
Autor: Pierre-Henri Ducluzeau, Christelle Ramé, Klaudia Błaszczyk, Pascal Froment, Patrycja Kurowska, Joëlle Dupont, Anthony Estienne, Agnieszka Rak, Alice Bongrani
Publikováno v: Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2021, 521, pp.1-12. ⟨10.1016/j.mce.2020.111113⟩
International audience; In female, energy metabolism influences reproductive function by modulating the Hypothalamic Pituitary Ovarian axis including the hypothalamic GnRH neuronal network, the pituitary gonadotropin secretion and the ovarian follicl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f041334463dccc136b9d252beed289
https://hal.inrae.fr/hal-03462585
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4
miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating SIRT1 (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase)
Autor: Marco Bianchi, Francesca Brambilla, Angela Raucci, Ileana Badi, Claudio Saccu, Andrea Polizzotto, Giulio Pompilio, Debora Ferri, Giuseppina Milano, Maurizio C. Capogrossi, Ilaria Burba, Luigi Mancinelli, Filippo Zeni
Publikováno v: Arteriosclerosis, thrombosis, and vascular biology, vol. 38, no. 9, pp. 2079-2090
Objective— Vascular calcification (VC) is age dependent and a risk factor for cardiovascular and all-cause mortality. VC involves the senescence-induced transdifferentiation of vascular smooth muscle cells (SMCs) toward an osteochondrogenic lineage
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199530fe14e86bc3c493ce4b85c3110c
https://doi.org/10.1161/atvbaha.118.311298
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5
Akademický článek
Targeting Sirtuin 1 for therapeutic potential: Drug repurposing approach integrating docking and molecular dynamics simulations.
Autor: Alrouji, Mohammed1 (AUTHOR), Alhumaydhi, Fahad A.2 (AUTHOR), Alsayari, Abdulrhman3,4 (AUTHOR), Sharaf, Sharaf E.5 (AUTHOR), Shafi, Sheeba6 (AUTHOR), Anwar, Saleha7 (AUTHOR), Shahwan, Moyad8 (AUTHOR), Atiya, Akhtar3 (AUTHOR) anas.shamsi18@gmail.com, Shamsi, Anas8 (AUTHOR) anas.shamsi18@gmail.com
Publikováno v: PLoS ONE. 12/20/2023, Vol. 18 Issue 12, p1-18. 18p.
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6
Akademický článek
A preliminary study of sirtuin-1 on angiotensin II-induced senescence and inflammation in abdominal aortic aneurysms.
Autor: Zhang, Xiangyu1 (AUTHOR) 3314023@zju.edu.cn, Chen, Huanhuan1 (AUTHOR), Pang, Tianshu1 (AUTHOR), Liang, Kai1 (AUTHOR), Mei, Jinhua1 (AUTHOR), Zhu, Yuefeng1 (AUTHOR), Yang, Jin1 (AUTHOR)
Publikováno v: CytoJournal. 9/27/2024, Vol. 21, p1-14. 14p.
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7
Therapeutic regulation of autophagy in hepatic metabolism
Autor: Niani Tiaye Bailey, Bilon Khambu, Gang Liu, Sophia Blessinger, Katherine Byrnes, Russell Scaife
Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 33-49 (2022)
Metabolic homeostasis requires dynamic catabolic and anabolic processes. Autophagy, an intracellular lysosomal degradative pathway, can rewire cellular metabolism linking catabolic to anabolic processes and thus sustain homeostasis. This is especiall
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58c0ac6db641c550d04c5a5c6ba5a1a
https://doi.org/10.1016/j.apsb.2021.07.021
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8
Clinical efficacies, underlying mechanisms and molecular targets of Chinese medicines for diabetic nephropathy treatment and management
Autor: Hai-Yong Chen, Yibin Feng, Cheng Zhang, Ning Wang, Sha Li, Guoyi Tang
Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2749-2767 (2021)
Diabetic nephropathy (DN) has been recognized as a severe complication of diabetes mellitus and a dominant pathogeny of end-stage kidney disease, which causes serious health problems and great financial burden to human society worldwide. Conventional
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d8ab4193adc39b242fa3c089b4f517
https://doi.org/10.1016/j.apsb.2020.12.020
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9
Akademický článek
LncRNA MALAT1 improves cerebral ischemia-reperfusion injury and cognitive dysfunction by regulating miR-142-3p/SIRT1 axis.
Autor: Meng, Shengxi1 (AUTHOR), Wang, Bing1 (AUTHOR), Li, Wentao2 (AUTHOR)
Publikováno v: International Journal of Neuroscience. Jul2023, Vol. 133 Issue 7, p740-753. 14p.
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10
The role of nutraceuticals as a complementary therapy against various neurodegenerative diseases: A mini-review
Autor: Hui-Fang Chiu, Chin-Kun Wang, Kamesh Venkatakrishnan
Publikováno v: Journal of Traditional and Complementary Medicine, Vol 10, Iss 5, Pp 434-439 (2020)
Journal of Traditional and Complementary Medicine
In recent times, many scientists have given great attention to nutraceuticals (complementary medicine) as it widely used for promoting health status. In particular for the prevention and treatment of various neurological diseases or disorders without
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0f0bc227bf2031dfbc2afc233615df
http://www.sciencedirect.com/science/article/pii/S2225411020301425
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