Zobrazeno 1 - 10
of 551
pro vyhledávání: '"SIRT-1"'
Publikováno v:
Journal of Holistic Integrative Pharmacy, Vol 5, Iss 3, Pp 205-214 (2024)
Endothelial inflammation injury is a key mechanism that occurs in the pathological processes of various cardiovascular diseases. Puerarin (PUE) is an isoflavone compound with strong antioxidant properties and the main active component isolated from t
Externí odkaz:
https://doaj.org/article/48d9b3a1ea764c289723a1822bc26d76
Autor:
Mohammad Hassan Sohouli, Ghazaleh Eslamian, Pejman Rohani, Hamid Zand, Nathalia Sernizon Guimarães
Publikováno v:
BMC Nutrition, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Background Recent evidence shows the role of sirtuin 1(SIRT1), a family of evolutionarily conserved proteins, as a potential therapeutic target in the prevention and treatment of obesity and metabolic diseases. Some evidence shows the modera
Externí odkaz:
https://doaj.org/article/2aeed546100941b3839a50ff5ec617ce
Autor:
Md. Musa Hossain, Amit K. Mishra, Ajay K. Yadav, Md. Ismail, Teja Naveen Sata, Amrendra K. Sah, Arnab Banik, Gopal Sharma, Senthil K. Venugopal
Publikováno v:
Annals of Hepatology, Vol 30, Iss 1, Pp 101758- (2025)
Introduction and Objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) is one of the primary causes of chronic liver disease and may lead to liver cirrhosis and hepatocellular carcinoma. Recent reports suggested that DEAD-box R
Externí odkaz:
https://doaj.org/article/936fa91ccc4f41e89b60e1f21aa61ee3
Autor:
Alaa Sirwi, Nesrine S. El-Sayed, Dina A.I. Albadawi, Abdulrahman E. Koshak, Sabrin R.M. Ibrahim, Gamal A. Mohamed, Hossam M. Abdallah, Mostafa A. Rabie
Publikováno v:
Scientific African, Vol 26, Iss , Pp e02470- (2024)
Costunolide (COST), a sesquiterpene lactone, has demonstrated promising potential in molecular docking studies targeting key proteins associated with Parkinson's disease (PD), particularly AMP-activated protein kinase (AMPK) and sirtuin-1 (SIRT1). Bu
Externí odkaz:
https://doaj.org/article/5fcd520b81af4888a9e47a3dc30bde7f
Autor:
Hanaa Ramadan, Nadia Moustafa, Rasha Rashad Ahmed, Ahmed A.G. El-Shahawy, Zienab E. Eldin, Suhailah S. Al-Jameel, Kamal Adel Amin, Osama M. Ahmed, Manal Abdul-Hamid
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35636- (2024)
The current study inspects the therapeutic effects of orally ingested insulin-loaded chitosan nanobeads (INS-CsNBs) with a pectin-dextrin (PD) coating on streptozotocin (STZ)-induced diabetes in Wistar rats. The study also assessed antioxidant effect
Externí odkaz:
https://doaj.org/article/71c89b324694463f9d50d8cf732de2ba
Autor:
Sirwi, Alaa a, El-Sayed, Nesrine S. b, Albadawi, Dina A.I. a, Koshak, Abdulrahman E. a, Ibrahim, Sabrin R.M. c, Mohamed, Gamal A. a, Abdallah, Hossam M. a, Rabie, Mostafa A. b, ⁎
Publikováno v:
In Scientific African December 2024 26
Autor:
Xinyu Miao, Lingjun Rong, Bo Fu, Shaoyuan Cui, Zhaoyan Gu, Fan Hu, Yanhui Lu, Shuangtong Yan, Banruo Sun, Wenli Jiang, Yuting Zhang, Yanping Gong, Chunlin Li
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Astragalus polysaccharides (APS) have been verified to have antioxidative and antiaging activities in the mouse liver and brain. However, the effect of APS on aortic endothelial senescence in old rats and its underlying mechanism
Externí odkaz:
https://doaj.org/article/fddff627db46478a880ce09d3507ac75
Autor:
Ramadan, Hanaa a, Moustafa, Nadia a, Ahmed, Rasha Rashad a, El-Shahawy, Ahmed A.G. b, Eldin, Zienab E. b, Al-Jameel, Suhailah S. c, d, Amin, Kamal Adel c, d, Ahmed, Osama M. e, Abdul-Hamid, Manal a, ⁎
Publikováno v:
In Heliyon 15 August 2024 10(15)
Autor:
Hend M. Hassan, Nehal H. M. Abdel-Halim, Ibrahim El-Shenbaby, Manar A. Helmy, Maha O. Hammad, Ola A. Habotta, Eman M. El Nashar, Mansour A. Alghamdi, Rashid A. Aldahhan, Khulood M. Al-Khater, Basmah Almohaywi, Eman A. E. Farrag
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Administration of high doses of acetaminophen (APAP) results in liver injury. Oxidative stress and iron overload play roles in the pathogenesis of APAP-induced hepatotoxicity. The present study assessed the potential hepatoprotective ef
Externí odkaz:
https://doaj.org/article/d90b0ab757554828bb88ebb7d8bdd678
Autor:
Maha Alsunbul, Thanaa A. El-Masry, Enas I. El Zahaby, Mohamed M. S. Gaballa, Maysa M. F. El-Nagar
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1356 (2024)
Background: Doxorubicin (DOX) is a widely used chemotherapeutic agent; nevertheless, cardiotoxicity limits its effectiveness. Orlistat (Orli) is an irreversible lipase enzyme inhibitor with poor solubility and bioavailability. Furthermore, Orli has a
Externí odkaz:
https://doaj.org/article/f1a115694ff044f598cba9a8011b0372