Zobrazeno 1 - 10
of 130
pro vyhledávání: '"SIMON A. MCG. THOM"'
Publikováno v:
Royal Society Open Science, Vol 10, Iss 6 (2023)
This study investigated the possibility of using low-cost, handheld, retinal imaging devices for the automatic extraction of quantifiable measures of retinal blood vessels. Initially, the available handheld devices were compared using a Zeiss model e
Externí odkaz:
https://doaj.org/article/4f96dc38c5004df9bf9b97f560757ad6
Autor:
John D. Sluyter, Carlos A. Camargo, Alistair W. Stewart, Debbie Waayer, Carlene M. M. Lawes, Les Toop, Kay‐Tee Khaw, Simon A. McG. Thom, Bernhard Hametner, Siegfried Wassertheurer, Kim H. Parker, Alun D. Hughes, Robert Scragg
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)
BackgroundThe effects of monthly, high‐dose, long‐term (≥1‐year) vitamin D supplementation on central blood pressure (BP) parameters are unknown. Methods and ResultsA total of 517 adults (58% male, aged 50–84 years) were recruited into a do
Externí odkaz:
https://doaj.org/article/ea05102f54e041ec856e7762ef807cb3
Autor:
Nicholas W. Witt, Neil Chapman, Simon A. McG. Thom, Alice V. Stanton, Kim H. Parker, Alun D. Hughes
Publikováno v:
Artery Research, Vol 4, Iss 3 (2010)
Conventionally, the relationship between parent and daughter vessels at vascular bifurcations has been expressed by the junction exponent (x), and deviations of this parameter from the optimal conditions predicted by Murray’s law (x = 3) have been
Externí odkaz:
https://doaj.org/article/4f20eaa05fa643edb712f7314dca1a30
Autor:
Peter S. Sever, Judith A. Finegold, Frances A. Wood, Susan Connolly, James P. Howard, Matthew J. Shun-Shin, Darrel P. Francis, Christine Norton, Jaimini Cegla, Christopher Rajkumar, Alexandra N. Nowbar, Ahran D. Arnold, Chris Stride, Simon A. McG. Thom, David Thompson
Publikováno v:
Journal of the American College of Cardiology
Background Most people who begin statins abandon them, most commonly because of side effects. Objectives The purpose of this study was to assess daily symptom scores on statin, placebo, and no treatment in participants who had abandoned statins. Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7907b0121d98cf26136cdc20f8fe3b74
http://europepmc.org/articles/PMC8453640
http://europepmc.org/articles/PMC8453640
Autor:
Boram Gu, Yu Huang, Emily Louise Manchester, Alun D. Hughes, Simon A. McG. Thom, Rongjun Chen, Xiao Yun Xu
Publikováno v:
Pharmaceutical research. 39(1)
Purpose This study establishes a multiphysics simulation platform for both conventional and targeted thrombolysis using tissue plasminogen activator (tPA). Based on our computational results, the effects of therapeutic parameters on the dynamics of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c637c634a0fd03d68324ecc64d653204
https://pubmed.ncbi.nlm.nih.gov/35044591
https://pubmed.ncbi.nlm.nih.gov/35044591
Autor:
Simon A. McG. Thom, David Thompson, Frances A. Wood, Alexandra N. Nowbar, Darrel P. Francis, James P. Howard, Matthew J. Shun-Shin, Peter S. Sever, Jaimini Cegla, Christine Norton, Judith A. Finegold, Christopher Rajkumar, Susan Connolly, Ahran D. Arnold, Chris Stride
Publikováno v:
New England Journal of Medicine. 383:2182-2184
N-of-1 Trial of a Statin, Placebo, or No Treatment Patients who had discontinued statins because of side effects received four bottles of a statin, four bottles of placebo, and four empty bottles, ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a7d5ba769cdae469edc37480f397c8
https://doi.org/10.1056/nejmc2031173
https://doi.org/10.1056/nejmc2031173
Autor:
Alun D. Hughes, Darrel P. Francis, Jamil Mayet, Anenta Ramakrishnan, Peter S. Sever, Neil R Poulter, Alice Stanton, Anoop S V Shah, Andrew Sharp, Simon A. McG. Thom
Publikováno v:
British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’
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A140
A142
A140
Background We have previously shown that tissue Doppler assessments of left ventricular (LV) diastolic function predict cardiac events in a hypertensive population over a period of 4 years. These out-performed traditional echocardiographic measures i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8570f4aacec6abcb0e0190e0bff9cc
http://hdl.handle.net/10044/1/93893
http://hdl.handle.net/10044/1/93893
Autor:
Alun D Hughes, Chloe Park, Justin Davies, Darrel Francis, Simon A McG Thom, Jamil Mayet, Kim H Parker
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59371 (2013)
ObjectivesAugmentation index (AIx) is widely used as a measure of wave reflection. We compared the relationship between AIx and age, height and sex with 'gold standard' measures of wave reflection derived from measurements of pressure and flow to est
Externí odkaz:
https://doaj.org/article/66a9bd40f2ab4e188139eca956291273
Autor:
Xuhan Liu, Boram Gu, Isabelle I. Salles-Crawley, Xiao Yun Xu, Michael Emerson, Colin Longstaff, Simon A. McG. Thom, Rongjun Chen, Yu Huang, Jie Ren, Li Yu, Kirk A. Taylor, Alun D. Hughes
Publikováno v:
Science Advances
Bioinspired nanovesicles enable activated platelet–targeted delivery of tissue plasminogen activator for effective thrombolysis.
Clinical use of tissue plasminogen activator (tPA) in thrombolytic therapy is limited by its short circulation tim
Clinical use of tissue plasminogen activator (tPA) in thrombolytic therapy is limited by its short circulation tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e402c795cc5a0f5858fca545c6d387
https://pubmed.ncbi.nlm.nih.gov/34078604
https://pubmed.ncbi.nlm.nih.gov/34078604
Autor:
Michael Foley, Darrel P. Francis, David Thompson, Justin E. Davies, Orbita Investigators, Pankaj Gupta, Rasha Al-Lamee, Prashanth Patel, Simon A. McG. Thom, Hakim M Dehbi
Publikováno v:
Pharmacology Research & Perspectives
e00710
Pharmacology Research & Perspectives, Vol 9, Iss 1, Pp n/a-n/a (2021)
e00710
Pharmacology Research & Perspectives, Vol 9, Iss 1, Pp n/a-n/a (2021)
Introduction The ORBITA trial of percutaneous coronary intervention (PCI) versus a placebo procedure for patients with stable angina was conducted across six sites in the United Kingdom via home monitoring and telephone consultations. Patients underw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2977e151be3e4ce984cf2f1eaed6f31c
https://pubmed.ncbi.nlm.nih.gov/33570248
https://pubmed.ncbi.nlm.nih.gov/33570248