Zobrazeno 1 - 8
of 8
pro vyhledávání: '"SILAC, stable isotope labelling by amino acids in cell culture"'
Publikováno v:
Matrix Biology Plus
Matrix Biology Plus, Vol 11, Iss, Pp 100066-(2021)
Matrix Biology Plus, Vol 11, Iss, Pp 100066-(2021)
The human skin has a highly developed extracellular matrix (ECM) that is vital for proper skin functioning, its 3D architecture playing a pivotal role in support and guidance of resident and invading cells. To establish relevant in vitro models mimic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8987d717333078847571bf504402385b
https://pubmed.ncbi.nlm.nih.gov/34435183
https://pubmed.ncbi.nlm.nih.gov/34435183
Autor:
James Cantley, Dorit Samocha-Bonet, P. Tess Whitworth, Daniel J. Fazakerley, David E. James, Lindsay E. Wu, Trevor J. Biden, Nigel Turner
Publikováno v:
Molecular Metabolism
A critical feature of obesity is enhanced insulin secretion from pancreatic β-cells, enabling the majority of individuals to maintain glycaemic control despite adiposity and insulin resistance. Surprisingly, the factors coordinating this adaptive β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b063d5eb9ce644eb16749522effb72f
Autor:
Agne, Kazlauskaite, Chandana, Kondapalli, Robert, Gourlay, David G, Campbell, Maria Stella, Ritorto, Kay, Hofmann, Dario R, Alessi, Axel, Knebel, Matthias, Trost, Miratul M K, Muqit
Publikováno v:
Biochemical Journal
We have previously reported that the Parkinson's disease-associated kinase PINK1 (PTEN-induced putative kinase 1) is activated by mitochondrial depolarization and stimulates the Parkin E3 ligase by phosphorylating Ser65 within its Ubl (ubiquitin-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::aa0af3494e76422dd3bf8afa4806b227
http://europepmc.org/articles/PMC4000136
http://europepmc.org/articles/PMC4000136
Publikováno v:
Biochemical Journal
The RBR (RING-BetweenRING-RING) or TRIAD [two RING fingers and a DRIL (double RING finger linked)] E3 ubiquitin ligases comprise a group of 12 complex multidomain enzymes. This unique family of E3 ligases includes parkin, whose dysfunction is linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cedff32799050efc0f1ef4664dad485
https://pubmed.ncbi.nlm.nih.gov/24576094
https://pubmed.ncbi.nlm.nih.gov/24576094
Publikováno v:
Bioscience Reports, Vol 34, Iss 1, p e00091 (2014)
Bioscience Reports
Bioscience Reports
Protein kinase inhibitors frequently have interesting effects that cannot be fully ascribed to the intended target kinase(s) but identifying additional targets that might explain the effects is not straightforward. By comparing two different inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fae0d7e2b25d40b4ebdc7cd6e124c5
https://doi.org/10.1042/bsr20130094
https://doi.org/10.1042/bsr20130094
Publikováno v:
Journal of Proteomics
Mass spectrometry, in the past five years, has increased in speed, accuracy and use. With the ability of the mass spectrometers to identify increasing numbers of proteins the identification of undesirable peptides (those not from the protein sample)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d180b6e30349013118d9b20773a14c
Scaffold-free 3D cell culture of primary skin fibroblasts induces profound changes of the matrisome.
Autor:
Vu B; Department of Biology, University of Fribourg, Chemin du Musée 10, CH-1700 Fribourg, Switzerland., Souza GR; Greiner Bio-One North America, Inc., 4238 Capital Drive, Monroe, NC 28110, USA., Dengjel J; Department of Biology, University of Fribourg, Chemin du Musée 10, CH-1700 Fribourg, Switzerland.
Publikováno v:
Matrix biology plus [Matrix Biol Plus] 2021 May 12; Vol. 11, pp. 100066. Date of Electronic Publication: 2021 May 12 (Print Publication: 2021).
Autor:
Wu LE; Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia ; School of Medical Sciences, University of New South Wales, New South Wales 2052, Australia., Samocha-Bonet D; Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia ; School of Medical Sciences, University of New South Wales, New South Wales 2052, Australia., Whitworth PT; Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia., Fazakerley DJ; Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia., Turner N; Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia ; School of Medical Sciences, University of New South Wales, New South Wales 2052, Australia., Biden TJ; Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia ; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Darlinghurst, New South Wales 2010, Australia., James DE; Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia ; The Charles Perkins Centre, School of Molecular Biosciences, School of Medicine, University of Sydney, New South Wales 2006, Australia., Cantley J; Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia ; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Darlinghurst, New South Wales 2010, Australia ; Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford OX1 3PT, United Kingdom.
Publikováno v:
Molecular metabolism [Mol Metab] 2014 Mar 14; Vol. 3 (4), pp. 465-73. Date of Electronic Publication: 2014 Mar 14 (Print Publication: 2014).