Zobrazeno 1 - 10
of 92
pro vyhledávání: '"SIGUO HAO"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundMesenchymal stem cells (MSCs) can alleviate graft-versus-host disease (GVHD) in hematopoietic stem cell transplantation (HSCT). MSCs-derived exosomes (MEXs) can mirror the biological function of their parent cells. Whether MEXs can alleviat
Externí odkaz:
https://doaj.org/article/baa53864a4bd43e7bbdc9fe84f1a2761
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Previous studies demonstrated that CD4+ T cells can uptake tumor antigen-pulsed dendritic cell-derived exosomes (DEXO), which harbor tumor antigen peptide/pMHC I complex and costimulatory molecules and show potent effects on inducing antitumor immuni
Externí odkaz:
https://doaj.org/article/a5eeb9eb66df435194cdfe0b8b39dc12
Autor:
Min Yang, Wenhao Zhang, Kang Yu, Peng Wang, Hua Jiang, Linjun Chen, Haitao Meng, Yiqin Weng, Rong Tao, Xin Huang, Chongyun Xing, Huamao Wang, Jiangbo Wan, Shasha Wang, Lihui Dai, Amanda Y. Hendrix, Jun Xiao, Wei Wang, Hong Ma, Siguo Hao, Jie Jin, Zonghai Li, Songfu Jiang
Publikováno v:
Haematologica, Vol 107, Iss 8 (2022)
Externí odkaz:
https://doaj.org/article/63ff07fbcfa542cca95bccf6286b5ee6
Autor:
Houli Zhao, Jieping Wei, Guoqing Wei, Yi Luo, Jimin Shi, Qu Cui, Mingfeng Zhao, Aibin Liang, Qing Zhang, Jianmin Yang, Xin Li, Jing Chen, Xianmin Song, Hongmei Jing, Yuhua Li, Siguo Hao, Wenjun Wu, Yamin Tan, Jian Yu, Yanmin Zhao, Xiaoyu Lai, Elaine Tan Su Yin, Yunxiong Wei, Ping Li, Jing Huang, Tao Wang, Didier Blaise, Lei Xiao, Alex H. Chang, Arnon Nagler, Mohamad Mohty, He Huang, Yongxian Hu
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Background Consolidative allogeneic hematopoietic stem cell transplantation is a controversial option for patients with relapsed/refractory acute lymphoblastic leukemia after chimeric antigen receptor T cell (CAR-T) therapy. We performed a m
Externí odkaz:
https://doaj.org/article/0d9754ba37f949e9a37c2ca215e508a1
Publikováno v:
Journal of International Medical Research, Vol 48 (2020)
Hemophagocytic lymphohistiocytosis (HLH) is a rare fatal clinical syndrome characterized by a hyperinflammatory condition caused by aberrantly activated macrophages and cytotoxic T cells, resulting in a cytokine storm and organ impairment. Lymphoma,
Externí odkaz:
https://doaj.org/article/0b71a57802b741329013c734056af663
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 1, Pp 240-254 (2017)
Background/Aims: Minimal residual leukemia cells (MRLs) are difficult to eradicate through traditional treatment and therefore remain to be a major threat to the long-term survival of leukemia patients. Tumor-derived exosomes (TEXs), which carry tumo
Externí odkaz:
https://doaj.org/article/ed4036d693d14ad68b618e0118bec928
Autor:
Jiangbo Wan, Fang Huang, Siguo Hao, Weiwei Hu, Chuanxu Liu, Wenhao Zhang, Xiaohui Deng, Linjun Chen, Liyuan Ma, Rong Tao
Publikováno v:
Cellular Physiology and Biochemistry, Vol 43, Iss 1, Pp 353-366 (2017)
Background/Aims: Tr1 cells can induce peripheral tolerance to self- and foreign antigens, and have been developed as a therapeutic tool for the induction of tolerance to transplanted tissue. We explored the feasibility of generating Tr1 cells by usin
Externí odkaz:
https://doaj.org/article/c689a5354f72418094ad7441f6559d93
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91463 (2014)
Dendritic cells (DCs) and tumor cell-derived exosomes have been used to develop antitumor vaccines. However, the biological properties and antileukemic effects of leukemia cell-derived exosomes (LEXs) are not well described. In this study, the biolog
Externí odkaz:
https://doaj.org/article/9aa2b4d5298342e0bead4cb406120fcc
Autor:
Huiqiang Huang, Rong Tao, Siguo Hao, Yu Yang, Hong Cen, Hui Zhou, Ye Guo, Liqun Zou, Junning Cao, Yunhong Huang, Jie Jin, Liling Zhang, Haiyan Yang, Xiaojing Xing, Huilai Zhang, Yanyan Liu, Kaiyang Ding, Qinzhou Qi, Xiaoli Zhu, Dan Zhu, Siyuan Wang, Teng Fang, Hangjun Dai, Qingmei Shi, Jason Yang
Publikováno v:
Journal of Clinical Oncology. 41:3032-3041
PURPOSE Relapsed or refractory extranodal natural killer/T-cell lymphoma (R/R ENKTL) is a rare and aggressive type of non-Hodgkin lymphoma with limited treatment options. This phase II study evaluated the efficacy and safety of sugemalimab, an anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::188158472fac2e68ba7d38f227677482
https://doi.org/10.1200/jco.22.02367
https://doi.org/10.1200/jco.22.02367
Autor:
Yuqin, Song, Yanyan, Liu, Zhi-Ming, Li, Lanfang, Li, Hang, Su, Zhengming, Jin, Xuelan, Zuo, Jianyuan, Wu, Hui, Zhou, Kunyan, Li, Chuan, He, Jianfeng, Zhou, Junyuan, Qi, Siguo, Hao, Zhen, Cai, Yijing, Li, Weiwei, Wang, Xiaojing, Zhang, Jianjun, Zou, Jun, Zhu
Publikováno v:
The Lancet Haematology. 9:e493-e503
Dysregulation of EZH2 has a crucial role in lymphomagenesis. We did a first-in-human study to assess the safety, pharmacokinetics, pharmacodynamics, and preliminary clinical activity of SHR2554, an oral EZH2 inhibitor, in patients with relapsed or re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dd78665d8b79af0782953d4e4826fa
https://doi.org/10.1016/s2352-3026(22)00134-x
https://doi.org/10.1016/s2352-3026(22)00134-x