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Akademický článek

JAZF1 heterozygous knockout mice show altered adipose development and metabolism

Autor: Jain Jeong, Soyoung Jang, Song Park, Wookbong Kwon, Si-Yong Kim, Soyoen Jang, Jiwon Ko, Si Jun Park, Su-geun Lim, Duhak Yoon, Junkoo Yi, Sanggyu Lee, Myoung Ok Kim, Seong-Kyoon Choi, Zae Young Ryoo

Publikováno v: Cell & Bioscience, Vol 11, Iss 1, Pp 1-17 (2021)

Abstract Background Juxtaposed with another zinc finger protein 1 (JAZF1) is associated with metabolic disorders, including type 2 diabetes mellitus (T2DM). Several studies showed that JAZF1 and body fat mass are closely related. We attempted to eluc

Externí odkaz: https://doaj.org/article/0d6d65bda325432488f69c3c0bac6acc

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Akademický článek

Protective Effect of Iris germanica L. Rhizome-Derived Exosome against Oxidative-Stress-Induced Cellular Senescence in Human Epidermal Keratinocytes

Autor: Ji-Seon Kim, Hyun-Jeong Lee, Eun-Jeong Yoon, Hyunsang Lee, Youngeun Ji, Youngseok Kim, Si-Jun Park, Junoh Kim, Seunghee Bae

Publikováno v: Applied Sciences, Vol 13, Iss 21, p 11681 (2023)

Plant-derived exosomes can exert therapeutic effects against various dermatological conditions. Several studies have demonstrated that plant-derived exosomes can have positive effects on the skin, preventing aging, hyperpigmentation, and hair loss. I

Externí odkaz: https://doaj.org/article/3a28e5d03c6c4ee683d6ec82914fe7c4

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Comparative analysis of the transcriptome and efficacy of bioactive Centella asiatica exosomes on skin cells

Autor: Min-Ha Kim, Eun Jeong Yoon, Jung Soo Kim, Si Jun Park, Hyunsang Lee

Studies on plant-derived natural products that have no side-effects have attracted great attention from the cosmetics industry. Plant-derived exosomes are nanovesicles (30–150 nm in size) that contain biomolecules, which protect plants from stress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8060ef4a0c01cf4948081fd1d3da0351
https://doi.org/10.21203/rs.3.rs-2787704/v1

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Jazf1 acts as a regulator of insulin‐producing β‐cell differentiation in induced pluripotent stem cells and glucose homeostasis in mice

Autor: Jain Jeong, Yonghun Sung, Si-Yong Kim, Soyoung Jang, Zae Young Ryoo, Seong-Kyoon Choi, Dongjun Kim, Si Jun Park, Myoung Ok Kim, Wookbong Kwon, Song Park

Publikováno v: The FEBS Journal. 288:4412-4427

Genetic susceptibility of type 2 diabetes and Juxtaposed with another zinc finger protein 1 (Jazf1) has been reported; however, the precise role of Jazf1 in metabolic processes remains elusive. In this study, using Jazf1-knockout (KO)-induced pluripo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaff82b9e4be30ebdf217149aad6d6e6
https://doi.org/10.1111/febs.15751

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Effects of Dimethyl Sulfoxide on the Pluripotency and Differentiation Capacity of Mouse Embryonic Stem Cells

Autor: Sung Hyun Kim, Zae-Young Ryoo, Song Park, Mee-Hyun Lee, Hai Huang, Jae Jung Ha, Junkoo Yi, Myoungok Kim, Si-Jun Park, Dae-Hyun Kim

Publikováno v: Cellular Reprogramming. 22:244-253

Mouse embryonic stem cells (mESCs) go through self-renewal in the existence of the cytokine leukemia inhibitory factor (LIF). LIF is added to the mouse stem cells culture medium, and its removal results in fast differentiation. Dimethyl sulfoxide (DM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d122f174cdaa3ee1ef54846f43aeb90
https://doi.org/10.1089/cell.2020.0006

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