Síntese e avaliação biológica de fluoróforos baseados em curcumina

Autor: Ferreira, Joana Raquel Mendes

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Curcumin is a natural compound obtained from the rhizome of Curcuma longa. It has several properties of clinical interest such as antitumoral and antimicrobial properties and has been suggested as a photosensitizer in photodynamic therapy as an alter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f35953f7380768e2ce606509d8bb6bc6
http://hdl.handle.net/10773/30594

Cytotoxic phenanthroline derivatives alter metallostasis and redox homeostasis in neuroblastoma cells

Autor: Giuseppe Arena, Nicola Margiotta, Irina Naletova, Alessandra Curci, Giovanni Natile, Diego La Mendola, Cristina Satriano, V. G. Nicoletti, Enrico Rizzarelli

Publikováno v: Oncotarget

Copper homeostasis is generally investigated focusing on a single component of the metallostasis network. Here we address several of the factors controlling the metallostasis for neuroblastoma cells (SH-SY5Y) upon treatment with 2,9-dimethyl-1,10-phe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c23edd0db3e25b1e0ac04359af45671
http://hdl.handle.net/20.500.11769/360441

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The antimalarial drug quinine interferes with serotonin biosynthesis and action

Autor: Sarah M. Tindall, Karen Swift, Simon V. Avery, Kevin C. F. Fone, Farida Hanim Islahudin, Kang Nee Ting, Richard J. Pleass, Ian R. Mellor, Hans Erik Mølager Christensen

Publikováno v: Islahudin, F, Tindall, S M, Mellor, I R, Swift, K, Christensen, H E M, Fone, K C F, Pleass, R J, Ting, K-N & Avery, S V 2014, ' The antimalarial drug quinine interferes with serotonin biosynthesis and action ', Scientific Reports, vol. 4, 3618 . https://doi.org/10.1038/srep03618
Scientific Reports

The major antimalarial drug quinine perturbs uptake of the essential amino acid tryptophan and patients with low plasma tryptophan are predisposed to adverse quinine reactions; symptoms of which are similar to indications of tryptophan depletion. As

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f244bec9e289ab069114065745a74fd

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