Výsledky vyhledávání

Akademický článek

Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma

Autor: Tianyi Ye, Alok K. Mishra, Shahid Banday, Rui Li, Kai Hu, Madison M. Coleman, Yi Shan, Shreya Roy Chowdhury, Lin Zhou, Magnolia L. Pak, Tessa M. Simone, Sunil K. Malonia, Lihua Julie Zhu, Michelle A. Kelliher, Michael R. Green

Publikováno v: Cell Reports, Vol 43, Iss 5, Pp 114211- (2024)

Summary: Multiple myeloma (MM) remains an incurable hematological malignancy demanding innovative therapeutic strategies. Targeting MYC, the notorious yet traditionally undruggable oncogene, presents an appealing avenue. Here, using a genome-scale CR

Externí odkaz: https://doaj.org/article/cbacef1a6c3c4564a194c75094fa53fc

Zobrazit plný text záznamu

Akademický článek

Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer

Publikováno v: Cell Reports, Vol 43, Iss 4, Pp 114041- (2024)

Summary: CD24 is frequently overexpressed in ovarian cancer and promotes immune evasion by interacting with its receptor Siglec10, present on tumor-associated macrophages, providing a “don’t eat me” signal that prevents targeting and phagocytos

Externí odkaz: https://doaj.org/article/51c10ad4e53242b1b570a3e817e3e103

Zobrazit plný text záznamu

Akademický článek

Prevalence of Extended-Spectrum β-Lactamases (ESBLs) Producing Aeromonas spp. Isolated from Lamellidens marginalis (Lamark, 1819) of Sewage-Fed Wetland: A Phenotypic and Genotypic Approach

Autor: Debasmita Mohanty, Basanta Kumar Das, Punam Kumari, Saikat Dey, Asit Kumar Bera, Amiya Kumar Sahoo, Shubhankhi Dasgupta, Shreya Roy

Publikováno v: Microorganisms, Vol 12, Iss 4, p 723 (2024)

The global rise of zoonotic bacteria resistant to multiple antimicrobial classes and the growing occurrence of infections caused by Aeromonas spp. resistant to β-lactam antibiotics pose a severe threat to animal and human health. However, the contri

Externí odkaz: https://doaj.org/article/103e2321a1cc45c9b9610f9ce3d1fd16

Zobrazit plný text záznamu

Akademický článek

Stock Status of a Few Small Indigenous Fish Species Exploited in the River Ganga, India

Autor: Archisman Ray, Basanta Kumar Das, Dibakar Bhakta, Canciyal Johnson, Shreya Roy, Subhadeep Das Gupta, Soumya Prasad Panda, Raju Baitha

Publikováno v: Fishes, Vol 8, Iss 12, p 572 (2023)

The River Ganga produces a substantial amount of its fish from small native species, defined here as those with a maximum length of 25 cm. The FiSAT program was utilized to estimate stock assessments of four important small indigenous species from th

Externí odkaz: https://doaj.org/article/bdb94dda6c5e4adbbd72135f9c2204c9

Zobrazit plný text záznamu

Akademický článek

Pediatric to adult primary care transition for medically complex youth: A tale of learning from challenges experienced implementing a pilot project during COVID-19

Autor: Reem Hasan, Reyna Lindert, Danielle Sullivan, Shreya Roy, Alison J. Martin

Publikováno v: Health Care Transitions, Vol 1, Iss , Pp 100027- (2023)

Purpose: The aim of our article is to describe our learning based on challenges encountered implementing two related pediatric to adult primary care transition pilots for medically complex adolescents and young adults as part of the Children with Med

Externí odkaz: https://doaj.org/article/1339350ee0834830ab7bd1361f2b5aea

Zobrazit plný text záznamu

Akademický článek

Lysophosphatidic Acid Promotes Epithelial to Mesenchymal Transition in Ovarian Cancer Cells by Repressing SIRT1

Autor: Upasana Ray, Sib Sankar Roy, Shreya Roy Chowdhury

Publikováno v: Cellular Physiology and Biochemistry, Vol 41, Iss 2, Pp 795-805 (2017)

Background/Aims: Epithelial-to-mesenchymal transition (EMT) plays an essential role in the transition from early to invasive phenotype, however the underlying mechanisms still remain elusive. Herein, we propose a mechanism through which the class-III

Externí odkaz: https://doaj.org/article/faf10cb1afd0448d92e92b4afe710507

Zobrazit plný text záznamu