Zobrazeno 1 - 10
of 30
pro vyhledávání: '"SHR, spontaneously hypertensive rat"'
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Hypertension is regulated by immunological components. Spontaneously hypertensive rats (SHR) display a large population of proinflammatory CD161 + immune cells. We investigated the effect of early post-natal gut microbiota on the development of the i
Externí odkaz:
https://doaj.org/article/9f586fd299004aa5b58760fd052fb563
Autor:
Vera Maria Morsch, Karine Paula Reichert, Milagros Fanny Vera Castro, Naiara Stefanello, Vanessa Valéria Miron, Andréia Machado Cardoso, Maria Rosa Chitolina Schetinger, Charles Elias Assmann, Nathieli B. Bottari
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss, Pp 111273-(2021)
Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy
Graphical abstract
Highlights • The coexistence of diabetes and hypertension represents a major risk factor for the onset of cardiovascular problems. • The purinergic signaling pathway constitutes a ubiquitous system of cell–cell communica
Highlights • The coexistence of diabetes and hypertension represents a major risk factor for the onset of cardiovascular problems. • The purinergic signaling pathway constitutes a ubiquitous system of cell–cell communica
Autor:
Arina G. Shokhina, Gijsbert J. van Belle, A. A. Borodinova, Dörthe M. Katschinski, Vsevolod V. Belousov, M. S. Pochechuev, Aleksei M. Zheltikov, Anastasiya S. Panova, Roman I. Raevskii, Viktor S. Tarabykin, Marcus Conrad, Ilya V. Kelmanson, Thorsten R. Doeppner, Valeriy V. Pak, Aleksandr A. Moshchenko, Ivan Bogeski, Alexandra Ivanova, Yulia G. Ermakova, Maxim A. Solotenkov, Ilya V. Fedotov, Daria A. Kotova, Pavel M. Balaban, E. A. Stepanov, Dmitry S. Bilan, Mathias Bähr, Andrei B. Fedotov, Alexander I. Kostyuk
Publikováno v:
Redox Biol. 48:102178 (2021)
Redox Biology
Redox Biology, Vol 48, Iss, Pp 102178-(2021)
Redox Biology
Redox Biology, Vol 48, Iss, Pp 102178-(2021)
Ischemic cerebral stroke is one of the leading causes of death and disability in humans. However, molecular processes underlying the development of this pathology remain poorly understood. There are major gaps in our understanding of metabolic change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5efeb3d788e8ec892843d2b9cf08ecc
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63520
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63520
Publikováno v:
Cellular Signalling
Stroke is the 2nd leading cause of death worldwide and the leading cause of physical disability and cognitive issues. Although we have made progress in certain aspects of stroke treatment, the consequences remain substantial and new treatments are ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f959631fa4ab01749588df72a511465d
https://eprints.gla.ac.uk/223969/2/223969.pdf
https://eprints.gla.ac.uk/223969/2/223969.pdf
Autor:
Hotaik Sung, Gi Soo Youn, Haripriya Gupta, Sang Jun Yoon, Hyeong Seob Kim, Na Young Lee, Ye Rin Choi, Min Jea Shin, Seul Ki Kim, Ki Tae Suk
Publikováno v:
Journal of Ginseng Research
Journal of Ginseng Research, Vol 45, Iss 3, Pp 380-389 (2021)
Journal of Ginseng Research, Vol 45, Iss 3, Pp 380-389 (2021)
Metabolic syndrome (MS) refers to a clustering of at least three of the following medical conditions: high blood pressure, abdominal obesity, hyperglycemia, low high-density lipoprotein level, and high serum triglycerides. MS is related to a wide ran
Publikováno v:
The Journal of Biological Chemistry
Bastrup, J A, Aalkjær, C & Jepps, T A 2022, ' Identification of novel proteins and mechanistic pathways associated with early-onset hypertension by deep proteomic mapping of resistance arteries ', Journal of Biological Chemistry, vol. 298, no. 1, 101512 . https://doi.org/10.1016/j.jbc.2021.101512
Bastrup, J A, Aalkjær, C & Jepps, T A 2022, ' Identification of novel proteins and mechanistic pathways associated with early-onset hypertension by deep proteomic mapping of resistance arteries ', Journal of Biological Chemistry, vol. 298, no. 1, 101512 . https://doi.org/10.1016/j.jbc.2021.101512
Resistance arteries are small blood vessels that create resistance to blood flow. In hypertension, resistance arteries undergo remodeling, affecting their ability to contract and relax appropriately. To date, no study has mapped the hypertension-rela
Akademický článek
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Autor:
Abdel A. Abdel-Rahman, Noha N. Nassar
Publikováno v:
Journal of Advanced Research, Vol 6, Iss 3, Pp 331-340 (2015)
Journal of Advanced Research
Journal of Advanced Research
Graphical abstract
Adenosine is implicated in the modulation of cardiovascular responses either at the peripheral or at central level in experimental animals. However, there are no dedicated reviews on the involvement of adenosine in mediating t
Adenosine is implicated in the modulation of cardiovascular responses either at the peripheral or at central level in experimental animals. However, there are no dedicated reviews on the involvement of adenosine in mediating t
Autor:
Lamia, Heikal, Anna, Starr, Dania, Hussein, Jesus, Prieto-Lloret, Phil, Aaronson, Lea Ann, Dailey, Manasi, Nandi
Publikováno v:
JACC. Basic to Translational Science
Visual Abstract
Highlights • Tetrahydrobiopterin is an essential cofactor for NO production. • Limitation of endogenous tetrahydrobiopterin reduces NO bioavailability, enhances oxidative stress, and impairs vascular function. • Orally supp
Highlights • Tetrahydrobiopterin is an essential cofactor for NO production. • Limitation of endogenous tetrahydrobiopterin reduces NO bioavailability, enhances oxidative stress, and impairs vascular function. • Orally supp
Publikováno v:
Archives of Cardiovascular Diseases
Summary The discovery of angiotensin-I-converting enzyme 2 (ACE2) and a (pro)renin receptor has renewed interest in the physiology of the renin-angiotensin system (RAS). Through the ACE2/angiotensin-(1–7)/Mas counter-regulatory axis, ACE2 balances