Zobrazeno 1 - 10
of 47
pro vyhledávání: '"SHOTA MORIYA"'
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0307662 (2024)
Promising outcomes have been reported in elder patients with acute myeloid leukemia (AML) using combined therapy of venetoclax (VEN) and azacytidine (AZA) in recent years. However, approximately one-third of patients appear to be refractory to this t
Externí odkaz:
https://doaj.org/article/41c15908f9024d1583b15934784765e2
Autor:
Shota Moriya, Hiromi Kazama, Hirotsugu Hino, Naoharu Takano, Masaki Hiramoto, Shin Aizawa, Keisuke Miyazawa
Publikováno v:
PLoS ONE, Vol 18, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/00b3bbb8cd044e8baf6fb9baafd862b3
Autor:
Hideki Tanaka, Hirotsugu Hino, Shota Moriya, Hiromi Kazama, Masaya Miyazaki, Naoharu Takano, Masaki Hiramoto, Kiyoaki Tsukahara, Keisuke Miyazawa
Publikováno v:
Biochemistry and Biophysics Reports, Vol 22, Iss , Pp - (2020)
Tyrosine kinase inhibitors (TKIs) induce autophagy in many types of cancer cells. We previously reported that gefitinib (GEF) and imatinib (IMA) induce autophagy in epidermal growth factor receptor (EGFR) knock-out A549 and non-BCR-ABL-expressing leu
Externí odkaz:
https://doaj.org/article/c639655190624e29aa720337aaa658e3
Publikováno v:
Biochemistry and Biophysics Reports, Vol 11, Iss C, Pp 174-181 (2017)
In this study, we showed that the dual addition of glucosyl ceramide synthase and ceramidase inhibitors to A549 cell culture led to the possibility of ceramide channel formation via endogenous palmitoyl-ceramide accumulation with an increase in chole
Externí odkaz:
https://doaj.org/article/4c3d5b5298a144409535e9b5ad210318
Autor:
Kazuhiro Hirasawa, Shota Moriya, Kana Miyahara, Hiromi Kazama, Ayako Hirota, Jun Takemura, Akihisa Abe, Masato Inazu, Masaki Hiramoto, Kiyoaki Tsukahara, Keisuke Miyazawa
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0164529 (2016)
Autophagy, a self-digestive system for cytoplasmic components, is required to maintain the amino acid pool for cellular homeostasis. We previously reported that the macrolide antibiotics azithromycin (AZM) and clarithromycin (CAM) have an inhibitory
Externí odkaz:
https://doaj.org/article/b41545854e87476c9c986f8449422fe2
Autor:
Masaki Hiramoto, Keisuke Miyazawa, Akihisa Abe, Hiroko Kokuba, Shota Moriya, Atsuo Takeda, Kiyoaki Tsukahara, Hirotsugu Hino, Naoharu Takano
Publikováno v:
International Journal of Oncology
The proton pump inhibitor lansoprazole (LPZ) inhibits the growth of several cancer cell lines, including A549 and CAL 27. We previously reported that macrolide antibiotics such as azithromycin (AZM) and clarithromycin (CAM) potently inhibit autophagi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8d6f2ada77ba30f64072600dbdd261
http://europepmc.org/articles/PMC7646592
http://europepmc.org/articles/PMC7646592
Autor:
Naoharu Takano, Keisuke Miyazawa, Shota Moriya, Hirotsugu Hino, Hiroko Kokuba, Shinsuke Miyazawa
Publikováno v:
Breast Cancer. 27:225-235
Vitamin K2 (VK2) has been reported to induce apoptosis in many types of cancer cells including leukemia. However, there are no precise reports regarding the breast cancer cells. From the stand point of clinical implications of VK2 including chemoprev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac38eb6179ec879fa8c4d0fb11fa371a
https://doi.org/10.1007/s12282-019-01012-y
https://doi.org/10.1007/s12282-019-01012-y
Autor:
Kazuhiro Hattori, Keisuke Miyazawa, Keitaro Miyake, Kiyoaki Tsukahara, Naoharu Takano, Hiromi Kazama, Masaki Hiramoto, Shota Moriya
Publikováno v:
Oncology Letters
Following surgery and chemoradiation, ~50% of patients with locally advanced head and neck tumors experience relapse within the first two years, with a poor prognosis. Therefore, a novel therapeutic approach is required. The aim of the present study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430bd5841d438d139b82567e766df02d
http://europepmc.org/articles/PMC8323012
http://europepmc.org/articles/PMC8323012
Autor:
Naoharu Takano, Hiroko Kokuba, Masaki Hiramoto, Shinji Abe, Keisuke Miyazawa, Shota Moriya, Kazutoshi Toriyama, Hiromi Kazama
Publikováno v:
Cancer Science
Cancer cells use autophagy for growth, survival, and cytoprotection from chemotherapy. Therefore, autophagy inhibitors appear to be good candidates for cancer treatment. Our group previously reported that macrolide antibiotics, especially azithromyci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde840fd0a9674f67a68e77b9ddf5602
https://pubmed.ncbi.nlm.nih.gov/34051014
https://pubmed.ncbi.nlm.nih.gov/34051014
Autor:
Naoharu Takano, Hideki Tanaka, Keisuke Miyazawa, Hiromi Kazama, Masaki Hiramoto, Shota Moriya, Hirotsugu Hino, Kiyoaki Tsukahara, Masaya Miyazaki
Publikováno v:
Biochemistry and Biophysics Reports, Vol 22, Iss, Pp-(2020)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Tyrosine kinase inhibitors (TKIs) induce autophagy in many types of cancer cells. We previously reported that gefitinib (GEF) and imatinib (IMA) induce autophagy in epidermal growth factor receptor (EGFR) knock-out A549 and non-BCR-ABL-expressing leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a798b133558b791375cccda8218e55
http://www.sciencedirect.com/science/article/pii/S2405580820300595
http://www.sciencedirect.com/science/article/pii/S2405580820300595