Zobrazeno 1 - 10
of 197
pro vyhledávání: '"SHOGO NOMURA"'
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Pocock-Simon’s minimisation method has been widely used to balance treatment assignments across prognostic factors in randomised controlled trials (RCTs). Previous studies focusing on the survival outcomes have demonstrated that
Externí odkaz:
https://doaj.org/article/f6e5d98204e14455805aeb128f27ccc1
Autor:
Hiroshi Imaoka, Masafumi Ikeda, Shogo Nomura, Chigusa Morizane, Takuji Okusaka, Masato Ozaka, Satoshi Shimizu, Kentaro Yamazaki, Naohiro Okano, Kazuya Sugimori, Hirofumi Shirakawa, Nobumasa Mizuno, Sohei Satoi, Hironori Yamaguchi, Rie Sugimoto, Kunihito Gotoh, Keji Sano, Akinori Asagi, Kazuyoshi Nakamura, Makoto Ueno
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The prognosis of advanced biliary tract cancer (BTC) patients remains poor due to limited efficacy of chemotherapy and difficulties in management. Thus, prediction of survival is crucial for the clinical management of advanced BTC. The aim w
Externí odkaz:
https://doaj.org/article/e3baf138902d49fc89d0cce9781a3f2f
Autor:
Satoshi Yuki, Kentaro Yamazaki, Yu Sunakawa, Hiroya Taniguchi, Hideaki Bando, Manabu Shiozawa, Tomohiro Nishina, Hisateru Yasui, Yoshinori Kagawa, Naoki Takahashi, Tadamichi Denda, Taito Esaki, Hisato Kawakami, Hironaga Satake, Atsuo Takashima, Nobuhisa Matsuhashi, Takeshi Kato, Chiharu Asano, Yukiko Abe, Shogo Nomura, Takayuki Yoshino
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 18702-18716 (2023)
Abstract Background Several biomarkers have been established for metastatic colorectal cancer (mCRC). We investigated whether plasma angiogenesis factors could predict the efficacy of biologics combined with chemotherapy in first‐line (1L) treatmen
Externí odkaz:
https://doaj.org/article/3ebebc37f7d94a9b970dc82f9c2f0539
Autor:
Shin Kobayashi, Shinichiro Takahashi, Shogo Nomura, Motohiro Kojima, Masashi Kudo, Motokazu Sugimoto, Masaru Konishi, Naoto Gotohda, Hiroya Taniguchi, Takayuki Yoshino
Publikováno v:
Cancer Medicine, Vol 10, Iss 20, Pp 6998-7011 (2021)
Abstract Despite reports on poor survival outcomes after hepatectomy for colorectal liver metastases (CRLM) with BRAF V600E mutation (mBRAF) exist, the role of mBRAF testing for technically resectable cases remains unclear. A single‐center retrospe
Externí odkaz:
https://doaj.org/article/3abf120d5cdb473a84aaf93d623f609e
Autor:
Naoto Gotohda, Shogo Nomura, Manami Doi, Katsuyuki Karasawa, Takamasa Ohki, Yasuhiro Shimizu, Yoshitaka Inaba, Atsuya Takeda, Haruyuki Takaki, Hiroshi Anai, Masafumi Ikeda, Motokazu Sugimoto, Tetsuo Akimoto
Publikováno v:
JGH Open, Vol 4, Iss 4, Pp 722-728 (2020)
Abstract Background and Aim Surgical resection is the standard local therapy for patients with colorectal liver metastases (CRLM). However, elderly and vulnerable patients sometimes have various organ dysfunctions. We have to conduct nonsurgical loca
Externí odkaz:
https://doaj.org/article/c706438781e147cfb24362f2d167cb4d
Autor:
Tomohiro Enokida, Takenori Ogawa, Akihiro Homma, Kenji Okami, Shujiro Minami, Ayako Nakanome, Yasushi Shimizu, Daisuke Maki, Yuri Ueda, Takao Fujisawa, Atsushi Motegi, Akira Ohkoshi, Jun Taguchi, Koji Ebisumoto, Shogo Nomura, Susumu Okano, Makoto Tahara
Publikováno v:
Cancer Medicine, Vol 9, Iss 5, Pp 1671-1682 (2020)
Abstract Background Induction chemotherapy (IC) in locally advanced squamous cell carcinoma of the head and neck (LA‐SCCHN) often compromises compliance with subsequent chemoradiotherapy (CRT), which negatively affects outcomes. Here, we assessed t
Externí odkaz:
https://doaj.org/article/4167ef393f2548d2b02a6ccd8d374368
Autor:
Kota Yokosu, Hiroshi Tanabe, Shogo Nomura, Hirokazu Ozone, Motoaki Saito, Hirokuni Takano, Aikou Okamoto
Publikováno v:
Gynecologic Oncology Reports, Vol 37, Iss , Pp 100805- (2021)
The object of this study is to evaluate the clinical safety and efficacy of total parietal peritonectomy (TPP) in primary debulking surgery (PDS) for advanced ovarian cancer. This retrospective single-center study analyzed 16 patients with FIGO stage
Externí odkaz:
https://doaj.org/article/f4a2d9c6258d44f38a2567bb7f26e480
Autor:
Kohei Shitara, Satoshi Ueha, Shigeyuki Shichino, Hiroyasu Aoki, Haru Ogiwara, Tetsuya Nakatsura, Toshihiro Suzuki, Manami Shimomura, Toshiaki Yoshikawa, Kayoko Shoda, Shigehisa Kitano, Makiko Yamashita, Takayuki Nakayama, Akihiro Sato, Sakiko Kuroda, Masashi Wakabayashi, Shogo Nomura, Shoji Yokochi, Satoru Ito, Kouji Matsushima, Toshihiko Doi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Background Transient CD4+ T cell depletion led to the proliferation of tumor-specific CD8+ T cells in the draining lymph node and increased infiltration of PD-1+CD8+ T cells into the tumor, which resulted in strong anti-tumor effects in tumo
Externí odkaz:
https://doaj.org/article/f3fa5960399a4030b38ca80859495c2b
Autor:
Hideaki Bando, Atsushi Ohtsu, Takayuki Yoshino, Toshiki Masuishi, Hiroya Taniguchi, Daisuke Kotani, Yoshito Komatsu, Eiji Shinozaki, Takako Eguchi Nakajima, Taroh Satoh, Tomohiro Nishina, Taito Esaki, Masashi Wakabayashi, Shogo Nomura, Koji Takahashi, Hiromi Ono, Nami Hirano, Noriko Fujishiro, Nozomu Fuse, Akihiro Sato
Publikováno v:
ESMO Open, Vol 4, Iss 6 (2019)
Background BRAF V600E mutations are associated with aggressive biology and limited response to standard chemotherapy, especially during second-line and beyond therapies. BRAF V600E mutant and wild-type colorectal cancers (CRCs) differ in their expres
Externí odkaz:
https://doaj.org/article/d4dc360f8caa4a12beca9ac3e971093a
Autor:
Rumi Fujioka, Nobuo Mochizuki, Masafumi Ikeda, Akihiro Sato, Shogo Nomura, Satoshi Owada, Satoshi Yomoda, Katsuya Tsuchihara, Satoshi Kishino, Hiroyasu Esumi
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198219 (2018)
Arctigenin is evaluated for antitumor efficacy in patients with pancreatic cancer. It has an inhibitory activity on mitochondrial complex I.Therefore, plasma lactate level of patients after arctigenin administration was evaluated for biomarker of cli
Externí odkaz:
https://doaj.org/article/24d4eb1a3a7f4374959e74abd2746ab2