Zobrazeno 1 - 10
of 76
pro vyhledávání: '"SHOGO KUWAHARA"'
Autor:
Shogo Kuwahara, Tomoyuki Homma, Merime Ohshiro, Yoshinori Yamano, Hideki Maki, Jingoro Shimada, Toshihiko Hori
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:4300-4305
The pharmacokinetic (PK)/pharmacodynamic (PD) parameters and the antibacterial activity of S-013420, a novel bicyclolide, against Haemophilus influenzae and Streptococcus pneumoniae , including macrolide-resistant isolates, were investigated using an
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:2507-2512
The in vivo antibacterial activity of S-3578, a new parental cephalosporin, was compared with those of cefepime, ceftriaxone, ceftazidime, imipenem-cilastatin, and vancomycin. The efficacy of S-3578 against systemic infections caused by methicillin-r
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:923-931
The in vitro antibacterial activity of S-3578, a new parenteral cephalosporin, against clinical isolates was evaluated. The MICs of the drug at which 90% of the isolates were inhibited were 4 μg/ml for methicillin-resistant Staphylococcus aureus (MR
Autor:
Shogo Kuwahara, Toshio Goto, Satoru Matsumoto, Yuji Watanabe, Katsuyuki Maki, Etsuko Watabe, Fumio Matsumoto, Shuichi Tawara, Fumiaki Ikeda, Yoshimi Wakai
Publikováno v:
Antimicrobial Agents and Chemotherapy. 44:614-618
The efficacy of intravenous injection of FK463, a novel water-soluble lipopeptide, was evaluated in mouse models of disseminated candidiasis and aspergillosis and was compared with those of fluconazole (FLCZ) and amphotericin B (AMPH-B). In the candi
Autor:
Kazumi Otomo, Noriko Teratani, Katsuyuki Maki, Akira Yamada, Hidenori Ohki, Hisashi Takasugi, Yoshihiko Morishita, Masaki Tomishima, Hirokazu Tanaka, Fumiaki Ikeda, Koji Kawabata, Fumio Matsumoto, Shogo Kuwahara, Toshio Goto, Shuichi Tawara, Kazuo Sakane
Publikováno v:
Antimicrobial Agents and Chemotherapy. 44:57-62
The currently available antifungal drugs for the treatment of deep-seated mycoses are limited to amphotericin B (AMPH-B), azole compounds, and flucytosine. AMPH-B remains the drug of choice for the treatment of most fungal diseases because it has bro
Autor:
Tamako Harasaki, Takashi Fukuoka, Shogo Kuwahara, Satoshi Ohya, Mikie Kubota, Akiko Kitayama, Tetsufumi Koga, Yasuki Kamai, Harumi Kawada, Masayuki Iwata, Hiroshi Yasuda
Publikováno v:
Antimicrobial Agents and Chemotherapy. 42:23-27
The efficacy of CS-834, a novel oral carbapenem, was assessed by using a murine model of pneumonia caused by penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae and was compared with those of oral cephems, i.e., cefteram pivoxil,
Autor:
Isao Higashiyama, Shimaru Sasaki, Masayoshi Doi, Kiyoshi Motokawa, Tadashi Yoshida, Hiroshi Nagata, Shogo Kuwahara, Yoshihide Komatsu, Kazuhisa Murakami
Publikováno v:
Journal of Infection and Chemotherapy. 3:38-48
A new oral cephem antibiotic S-1090 was evaluated for its in vitro antibacterial activity in comparison with cefdinir, cefpodoxime, and cefaclor. S-1090 had fairly potent antibacterial activity when compared with cefdinir, cefpodoxime, and cefaclor.
Autor:
YASUHIRO MINE, YUJI WATANABE, HIROSHI SAKAMOTO, KAZUO HATANO, YOSHIMI WAKAI, TOSHIAKI KAMIMURA, SHUICHI TAWARA, SATORU MATSUMOTO, FUMIO MATSUMOTO, SHOGO KUWAHARA
Publikováno v:
The Journal of Antibiotics. 46:88-98
Autor:
YASUHIRO MINE, YUJI WATANABE, HIROSHI SAKAMOTO, KAZUO HATANO, KYOICHIRO KUNO, YASUYUKI HIGASHI, TOSHIAKI KAMIMURA, YOSHIMI MATSUMOTO, SHUICHI TAWARA, FUMIO MATSUMOTO, SHOGO KUWAHARA
Publikováno v:
The Journal of Antibiotics. 46:71-87
FK037 is a new parenteral cephalosporin, which offers some advantages over the commercially available parenteral cephalosporins. It demonstrated potent broad-spectrum activity against clinical isolates of Gram-positive bacteria including methicillin-
Autor:
Shogo Kuwahara, Hideki Maki, Takaji Fujimura, Yoshinori Yamano, Jingoro Shimada, Tomoyuki Homma
Publikováno v:
The Journal of antimicrobial chemotherapy. 65(7)
The in vitro activity of S-013420, a novel bicyclolide, was investigated.All test strains for this study were isolated from Japanese medical facilities. MICs were determined by the microbroth dilution method or agar dilution method according to the C