Zobrazeno 1 - 10
of 42
pro vyhledávání: '"SHIN-ICHIRO OHNO"'
Publikováno v:
Regenerative Therapy, Vol 18, Iss , Pp 117-126 (2021)
Introduction: Currently, embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be induced to differentiate at the cellular level but not to form mature tissues or organs suitable for transplantation. ESCs/iPSCs form immature tera
Externí odkaz:
https://doaj.org/article/22e1f9051a1b4131bc6dfe967f6b1cde
Autor:
Tomohiro Umezu, Masakatsu Takanashi, Yoshiki Murakami, Shin-ichiro Ohno, Kohsuke Kanekura, Katsuko Sudo, Kenichi Nagamine, Shin Takeuchi, Takahiro Ochiya, Masahiko Kuroda
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 199-208 (2021)
Extracellular vesicles derived from mammalian cells could be useful carriers for drug delivery systems (DDSs); however, with regard to clinical application, there are several issues to be overcome. Acerola (Malpighia emarginata DC.) is a popular heal
Externí odkaz:
https://doaj.org/article/98a34a5d2b004f99a8ad68ec25b1c86b
Autor:
Yuko Yamada, Masakatsu Takanashi, Katsuko Sudo, Shinobu Ueda, Shin-Ichiro Ohno, Masahiko Kuroda
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171957 (2017)
MicroRNA 29b (miR-29b) replacement therapy is effective for suppressing fibrosis in a mouse model. However, to develop clinical applications for miRNA mimics, the side effects of nucleic acid drugs have to be addressed. In this study, we focused on m
Externí odkaz:
https://doaj.org/article/2590509697614e49a7c25dd9ae3a40dc
Autor:
Masakatsu Takanashi, Katsuko Sudo, Shinobu Ueda, Shin-Ichiro Ohno, Yuko Yamada, Yasuhiro Osakabe, Hiroshi Goto, Yoshimichi Matsunaga, Akio Ishikawa, Yoshihiko Usui, Masahiko Kuroda
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
RNA interference (RNAi) has become a powerful tool for suppressing gene expression in vitro and in vivo. A great deal of evidence has demonstrated the potential for the use of synthetic small interfering RNAs (siRNAs) as therapeutic agents. However,
Externí odkaz:
https://doaj.org/article/3a5828a82d244f80a247abc262a8f872
Autor:
HIROYUKI KOMATSU, YOSHIHIKO USUI, AOI SUKEDA, YOSHINARI YAMAMOTO, SHIN-ICHIRO OHNO, KEISUKE GOTO, MASAHIKO KURODA, TOSHITAKA NAGAO, HIROSHI GOTO
Publikováno v:
American Journal of Ophthalmology. 249:49-56
Merkel cell polyomavirus (MCPyV) infection is a known to be a critical risk factor for the development of Merkel cell carcinoma (MCC). Various reports on cutaneous MCC have shown that the differences in clinicohistopathological characteristics depend
Publikováno v:
Clinical and Experimental Nephrology. 27:411-418
Publikováno v:
Regenerative Therapy, Vol 18, Iss, Pp 117-126 (2021)
Regenerative Therapy
Regenerative Therapy
Introduction Currently, embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be induced to differentiate at the cellular level but not to form mature tissues or organs suitable for transplantation. ESCs/iPSCs form immature terat
Autor:
Shin-ichiro Ohno, Yuichirou Harada, Masahiko Kuroda, Kosuke Oikawa, Shun-Ichi Ikeda, Koji Fujita, Masakatsu Takanashi, Katsuyoshi Kumagai, Hirotaka Nishi, Katsuko Sudo, Keiki Oikawa
Publikováno v:
Oncogene
Since cervical cancer still afflicts women around the world, it is necessary to understand the underlying mechanism of cervical cancer development. Infection with HPV is essential for the development of cervical intraepithelial neoplasia (CIN). In ad
Autor:
Asako Gondo, Suguru Saito, Shin-ichiro Ohno, Shouichirou Mineo, Koji Fujita, Yuichirou Harada, Yoshihiko Kanno, Keiki Oikawa, Masahiko Kuroda
Publikováno v:
Clinical and Experimental Nephrology. 23:1345-1356
Previous studies showed that microRNA-29b (miR-29b) inhibits renal fibrosis. Therefore, miR-29b replacement therapy represents a promising approach for treating renal fibrosis. However, an efficient method of kidney-targeted miRNA delivery has yet to
Autor:
Toshitaka Nagao, Atsushi Kurata, Masahiko Kuroda, Akira Saito, Shigeto Kobayashi, Akira Yamashina, Koji Fujita, Hiroshi Kamma, Hirotsugu Hashimoto, Shin-ichiro Ohno
Publikováno v:
Modern Rheumatology. 29:992-1001
Objectives: This study aimed to compare Takayasu arteritis (TAK) with giant cell arteritis (GCA) through immunohistochemistry principally of inflammatory cells; these two disorders may be o...