Zobrazeno 1 - 10
of 124
pro vyhledávání: '"SHIGEYUKI YOSHIFUJI"'
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 69:1109-1121
Publikováno v:
Chemical and Pharmaceutical Bulletin. 57:167-176
The Grignard, Wittig, Tebbe, Horner-Emmons, and Reformatsky reactions of the 4-oxoproline esters gave the corresponding 4-alylated or 4-alkylidenated products, respectively. The products were properly treated with bases to cause aromatization, giving
Publikováno v:
Chemical and Pharmaceutical Bulletin. 57:49-54
The short-step synthesis of the unsubstituted, 5-hydroxy- and 5-chloropiperidazine-3-carboxylic acids using an aza Diels-Alder reaction between the 1,3-diene and azodicarboxylate was described. This synthetic methodology could be used for the prepara
Publikováno v:
Chemical and Pharmaceutical Bulletin. 56:1310-1313
The ruthenium tetroxide (RuO(4)) oxidation of cyclic ene-carbamates resulted in the endo-cyclic carbon-carbon double bond cleavage to afford the corresponding omega-(N-formylamino)carboxylic acids in good yields. Substituted cyclic ene-carbamates der
Publikováno v:
Tetrahedron Letters. 42:2713-2716
The first synthesis of a pair of (R)- and (S)-piperidazine-3-phosphonic acids was performed via a one-pot process of hetero Diels–Alder reaction and Lewis acid-catalyzed phosphonylation. The absolute configuration of the target compounds was establ
Publikováno v:
Tetrahedron Letters. 49:2786-2788
The ruthenium tetroxide oxidation of cyclic N -acyl amines by a 10% NaIO 4 aqueous solution containing tert -butanol as a single layer system resulted in the endo -cyclic C–N bond cleavage to afford the ω-amino acids as almost sole products in goo
Publikováno v:
Chemical and Pharmaceutical Bulletin. 46:674-680
The hetero Diels-Alder adducts 6a-d derived from azodibenzoyl and cyclic dienes were oxidized by ruthenium tetroxide and transformed into meso-diaminodicarboxylic acids 12a-d via the new cyclic hydrazoacetic acids 9a-d.
Publikováno v:
Chemical and Pharmaceutical Bulletin. 45:255-259
Lactams derived from hetero Diels-Alder adducts were stereospecifically converted into cis-2, 4-pyrrolidinedicarboxylic acid and cis-2, 5-piperidinedicarboxylic acid by ruthenium tetroxide oxidation. Optically active (2S, 4S)-(-)-2, 4-pyrrolidinedica
Publikováno v:
Chemical and Pharmaceutical Bulletin. 52:160-162
The synthesis of hexahydropyridazine-3-phosphonic acid (piperidazine-3-phosphonic acid) was performed via a hetero-Diels-Alder reaction followed by Lewis acid-catalyzed phosphonylation. This two-step procedure was improved to a one-pot reaction.
Autor:
Shigeyuki Yoshifuji, Mamoru Kaname
Publikováno v:
Chemical and Pharmaceutical Bulletin. 43:1617-1620
Lycoperdic acid [(2S, 5'S)-2-amino-3-(5'-carboxy-2'-oxo-5'-tetrahydrofuranyl)propanoic acid], isolated from the mushroom Lycoperdon perlatum, was synthesized from trans-4-hydroxy-L-proline by a six-step route involving samarium diiodide (SmI2)-mediat