Zobrazeno 1 - 10
of 23
pro vyhledávání: '"SHAOJUN MEI"'
Autor:
Ambra Pozzi, Scott M. Williams, F. Peter Guengerich, John R. Falck, Jorge H. Capdevila, Megan M. Shuey, James M. Luther, Roy Zent, Shouzuo Wei, Shaojun Mei, Manuel Chiusa, Mahesha H. Gangadhariah, Lindsay N. Sausville
This file contains the primer sequence of CYP2C9* variants (Supplementary Table S1); the SNPs genotyped in the BioVU NSCLC study (Supplementary Table S2); quality control measures of SNPs in the BioVU NSCLC study (Supplementary Table S3); clinical an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308f7412116c1324a40a6f5c93f46538
https://doi.org/10.1158/0008-5472.22426270.v1
https://doi.org/10.1158/0008-5472.22426270.v1
Autor:
Ambra Pozzi, Scott M. Williams, F. Peter Guengerich, John R. Falck, Jorge H. Capdevila, Megan M. Shuey, James M. Luther, Roy Zent, Shouzuo Wei, Shaojun Mei, Manuel Chiusa, Mahesha H. Gangadhariah, Lindsay N. Sausville
Increased expression of cytochrome P450 CYP2C9, together with elevated levels of its products epoxyeicosatrienoic acids (EET), is associated with aggressiveness in cancer. Cytochrome P450 variants CYP2C9*2 and CYP2C9*3 encode proteins with reduced en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff77c3335eea0c969f51ecdd1f48097
https://doi.org/10.1158/0008-5472.c.6512281
https://doi.org/10.1158/0008-5472.c.6512281
Autor:
MARCELA BRISSOVA, HEATHER H. DURAI, SHAOJUN MEI, ANASTASIA COLDREN, COREY DAVIS, CONRAD REIHSMANN, ALEXANDER L. HOPKIRK, DANNIELLE GIBSON, RADHIKA ARAMANDLA, GREG POFFENBERGER, DIANE C. SAUNDERS, ALVIN C. POWERS, JOYCE C. NILAND, CARMELLA EVANS-MOLINA
Publikováno v:
Diabetes. 71
The Integrated Islet Distribution Program (IIDP) is currently the largest source of human islets for research in the U.S. The IIDP Human Islet Phenotyping Program (HIPP) provides standardized islet assessment and makes these data available to researc
Autor:
TIFFANY M. RICHARDSON, CHUNHUA DAI, RADHIKA ARAMANDLA, HEATHER H. DURAI, CONRAD REIHSMANN, COREY DAVIS, SHAOJUN MEI, DANNIELLE GIBSON, SHRISTI SHRESTHA, DIANE C. SAUNDERS, KATIE C. COATE, SIMON C. ROBSON, ALVIN C. POWERS, MARCELA BRISSOVA
Publikováno v:
Diabetes. 71
ATP release from β cell secretory vesicles during insulin exocytosis is postulated to modulate islet hormone secretion via purinergic signaling in an autocrine or paracrine manner. Ecto-enzymes, including a family of ectonucleotidases (NTPDase) , co
Autor:
Roy Zent, Mahesha Gangadhariah, James M. Luther, Megan M Shuey, Shaojun Mei, F. Peter Guengerich, Lindsay N. Sausville, Manuel Chiusa, J. Capdevila, Ambra Pozzi, Scott M. Williams, Shouzuo Wei, John R. Falck
Publikováno v:
Cancer Research. 78:4865-4877
Increased expression of cytochrome P450 CYP2C9, together with elevated levels of its products epoxyeicosatrienoic acids (EET), is associated with aggressiveness in cancer. Cytochrome P450 variants CYP2C9*2 and CYP2C9*3 encode proteins with reduced en
Autor:
Yan Gong, John D. Imig, Shaojun Mei, Wen-Hui Wang, John R. Falck, Raymond C. Harris, Jorge H. Capdevila, Nataliya Pidkovka
Publikováno v:
Journal of Biological Chemistry. 289:4377-4386
Hypertension is a major risk factor for cerebral, cardiovascular, and renal disease, and its prevalence and devastating consequences raises a need for new strategies for its early diagnosis and treatment. We show here that lack of a Cyp2c44 epoxygena
Autor:
Shaojun Mei, Cheng-Chia Wu, Katherine H. Gotlinger, Jennifer Cheng, Victor Garcia, John R. Falck, Vijaya L. Manthati, Fan Zhang, Michal L. Schwartzman, Yan Ding, Adam Weidenhammer, Jorge H. Capdevila
Publikováno v:
Journal of the American Society of Nephrology. 24:1288-1296
Although the mechanism underlying the effect of androgen on BP and cardiovascular disease is not well understood, recent studies suggest that 20-hydroxy-5,8,11,14-eicosatetraenoic acid (20-HETE), a primary cytochrome P450 4 (Cyp4)-derived eicosanoid,
Autor:
Michal L. Schwartzman, Yan Ding, Shaojun Mei, Frank Zhang, Adam Weidenhammer, Jorge H. Capdevila, Victor Garcia, Irina Dimitrova, John R. Falck, Cheng-Chia Wu
Publikováno v:
The FASEB Journal. 27
Autor:
Nataliya Pidkovka, Shaojun Mei, Reena Rao, Yan Gong, Raymond C. Harris, Wen-Hui Wang, Jorge H. Capdevila
Publikováno v:
The Journal of biological chemistry. 288(7)
The epithelial sodium channel (ENaC) participates in the regulation of plasma sodium and volume, and gain of function mutations in the human channel cause salt-sensitive hypertension. Roles for the arachidonic acid epoxygenase metabolites, the epoxye
Autor:
Yan Ding, Cheng-Chia Wu, Victor Garcia, Irina Dimitrova, Adam Weidenhammer, Frank Zhang, John R Falck, Shaojun Mei, Jorge Capdevila, Michal L Schwartzman
Publikováno v:
Hypertension. 60
20-Hydroxyeicosatetraenoic acid (20-HETE) promotes smooth muscle contraction and proliferation, endothelial dysfunction and activation and hypertension. We have previously demonstrated that 20-HETE mediates androgen-induced hypertension. This study e