Zobrazeno 1 - 10
of 10 582
pro vyhledávání: '"SH3"'
Autor:
Christopher M. Jones, Arndt Rohwedder, Kin Man Suen, Safoura Zahed Mohajerani, Antonio N. Calabrese, Sabine Knipp, Mark T. Bedford, John E. Ladbury
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35480- (2024)
Receptor tyrosine kinase (RTK) overexpression is linked to the development and progression of multiple cancers. RTKs are classically considered to initiate cytoplasmic signalling pathways via ligand-induced tyrosine phosphorylation, however recent ev
Externí odkaz:
https://doaj.org/article/756db033cc9a4969828da63cff6be9ba
Autor:
Boglarka Zambo, Evelina Edelweiss, Bastien Morlet, Luc Negroni, Matyas Pajkos, Zsuzsanna Dosztanyi, Soren Ostergaard, Gilles Trave, Jocelyn Laporte, Gergo Gogl
Publikováno v:
eLife, Vol 13 (2024)
Truncation of the protein-protein interaction SH3 domain of the membrane remodeling Bridging Integrator 1 (BIN1, Amphiphysin 2) protein leads to centronuclear myopathy. Here, we assessed the impact of a set of naturally observed, previously uncharact
Externí odkaz:
https://doaj.org/article/f5c33ef1efd744989b95c329d4a4ad45
Autor:
Sanda Win, Tin Aung Than, Neil Kaplowitz, Nicole Wong, Aliza Arya, Zin Thandar Win, Shwe Hlaing Win, Ei Hnin Phyu, Christina Kuemerle, Jake Suh, Sona Avanesyan, Pujan Prakash Dobaria, Hnin Wai Lwin, Sean Wong, Shannon Kaw, Samuel Wong, Kyaw Khaing Soe, Garmani Kyaw, Filbert Win Min Aung
Publikováno v:
Exploration of Digestive Diseases, Vol 3, Iss 1, Pp 42-68 (2024)
Mitochondria are present in all mammalian cells except matured red blood cells. Mitochondria consist of several metabolic pathways for glucose, fatty acids, amino acids, and bioenergetic pathways for ATP synthesis, membrane potential, and reactive ox
Externí odkaz:
https://doaj.org/article/1ebf96b0fd424014ae0a8d147fd50ef5
Autor:
Hyojin Um, Hoim Jeong, Beomgu Lee, Yerin Kim, Jihyeon Lee, Jong Seong Roh, Seung-Geun Lee, Hae Ryoun Park, William H. Robinson, Dong Hyun Sohn
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 53-60 (2023)
ABSTRACTThe WAVE regulatory complex (WRC) is involved in various cellular processes by regulating actin polymerization. The dysregulation of WRC components is associated with cancer development. ABI family member 3 (ABI3)/new molecule including SH3 (
Externí odkaz:
https://doaj.org/article/24f29e9025bb424ab19ed38ff7485c36
Akademický článek
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Akademický článek
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Publikováno v:
Ibrain, Vol 9, Iss 1, Pp 3-12 (2023)
Abstract This article aims to detect the effect of SAM domain, SH3 domain, and nuclear localization signal 1 (SAMSN1) in neonatal rats with neurological dysfunction induced by hypoxia and ischemia (HI). The HI model was created using 7‐day postnata
Externí odkaz:
https://doaj.org/article/1d9f29365aa24fdc992335a40b180140
Autor:
Lenka Koudelková, Markéta Pelantová, Zuzana Brůhová, Martin Sztacho, Vojtěch Pavlík, Dalibor Pánek, Jakub Gemperle, Pavel Talacko, Jan Brábek, Daniel Rösel
Publikováno v:
eLife, Vol 12 (2023)
The activation of Src kinase in cells is strictly controlled by intramolecular inhibitory interactions mediated by SH3 and SH2 domains. They impose structural constraints on the kinase domain holding it in a catalytically non-permissive state. The tr
Externí odkaz:
https://doaj.org/article/3b1c7c87d3bb4e7db96521db2ea11862
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 259 (2024)
Growth-factor-receptor-binding protein 2 (GRB2) is a non-enzymatic adaptor protein that plays a pivotal role in precisely regulated signaling cascades from cell surface receptors to cellular responses, including signaling transduction and gene expres
Externí odkaz:
https://doaj.org/article/ac8b55a6e85048a0acfe004bbd90e42a
Autor:
Neda S. Kazemein Jasemi, Mehrnaz Mehrabipour, Eva Magdalena Estirado, Luc Brunsveld, Radovan Dvorsky, Mohammad R. Ahmadian
Publikováno v:
Cells, Vol 13, Iss 2, p 195 (2024)
SRC homology 3 (SH3) domains are critical interaction modules that orchestrate the assembly of protein complexes involved in diverse biological processes. They facilitate transient protein–protein interactions by selectively interacting with prolin
Externí odkaz:
https://doaj.org/article/c7001b3fff9d4e5b9493001e5111db30