Zobrazeno 1 - 10
of 4 338
pro vyhledávání: '"SH-SY5Y cells"'
Autor:
Daiki Wakasugi, Shinji Kondo, Farhana Ferdousi, Seiya Mizuno, Akira Yada, Kenichi Tominaga, Satoru Takahashi, Hiroko Isoda
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Neuroinflammation is widely acknowledged as a characteristic feature of almost all neurological disorders and specifically in depression- and anxiety-like disorders. In recent years, there has been significant attention on natural
Externí odkaz:
https://doaj.org/article/aa38080127454026ba327a1978b6802f
Publikováno v:
Journal of King Saud University: Science, Vol 36, Iss 8, Pp 103319- (2024)
Objectives: Huntington's disease is an incurable neurodegenerative disease caused by a huntingtin gene defect; it causes changes in the brain, which affect movement and mental functions. The molecular mechanism still challenges the research to find t
Externí odkaz:
https://doaj.org/article/38d08d80b5e94e0aacb7cba2a691dbdf
Autor:
Jennifer McDonough, Naveen K. Singhal, Paulina M. Getsy, Katherine Knies, Zackery T. Knauss, Devin Mueller, James N. Bates, Derek S. Damron, Stephen J. Lewis
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
We have reported that D,L-thiol esters, including D-cysteine ethyl ester (D-CYSee), are effective at overcoming opioid-induced respiratory depression (OIRD) in rats. Our on-going studies reveal that co-injections of D-CYSee with multi-day morphine in
Externí odkaz:
https://doaj.org/article/b770ebd95e5f4062957719f54007718e
Autor:
Yajie Hu, Wei Zhao, Yaming Lv, Hui Li, Jiang Li, Mingmei Zhong, Dandan Pu, Fuping Jian, Jie Song, Yunhui Zhang
Publikováno v:
Virus Research, Vol 345, Iss , Pp 199386- (2024)
Coxsackievirus A16 (CV-A16) and coxsackievirus A10 (CV-A10), more commonly etiological agents of hand, foot and mouth disease (HFMD), are capable of causing severe neurological syndromes with high fatalities, but their neuropathogenesis has rarely be
Externí odkaz:
https://doaj.org/article/c4851c90090047179b5153b88c60a0ff
Autor:
Wen-Wen He, Xiao-Xiao Zeng, Xiao-Lan Qi, Chuan-Zhi Gui, Wei Liao, Xi Tu, Jie Deng, Yang-Ting Dong, Wei Hong, Yan He, Yan Xiao, Zhi-Zhong Guan
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 279, Iss , Pp 116467- (2024)
Background: Although the changes of mitogen-activated protein kinase (MAPK) pathway in the central nervous system (CNS) induced by excessive fluoride has been confirmed by our previous findings, the underlying mechanism(s) of the action remains uncle
Externí odkaz:
https://doaj.org/article/2a38e158828b4445aac9af2b63408a1b
Publikováno v:
Toxins, Vol 16, Iss 11, p 473 (2024)
Cyclopiazonic acid (CPA) is an indole-tetramic acid neurotoxin produced by Aspergillus and Penicillium genera present mainly in fruit, cereals and nuts. This study compares the cytotoxicity produced by CPA after 24, 48 and 72 h of exposure using both
Externí odkaz:
https://doaj.org/article/a470be7208ae465285c90757ea57002b
Publikováno v:
Plants, Vol 13, Iss 21, p 3076 (2024)
Lessertia frutescens (synonym Sutherlandia frutescens) is an important South African medicinal plant used traditionally to treat different human pathologies and is considered an adaptogenic plant. This study sought to isolate compounds from the plant
Externí odkaz:
https://doaj.org/article/18c6c554ddaf4eeab6eedf2ae6a065c0
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 8115-8116 (2024)
Liu J, Kang Y, Yin S, et al. Int J Nanomedicine. 2017;12:8085–8099. The authors have advised the control images for Figure 4A and B were the same to represent the one and the same control group. To alleviate any potential confusion this may have cr
Externí odkaz:
https://doaj.org/article/ec46cfacc91f4de19c397d7107d0e600
Akademický článek
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Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the accumulation of amyloid beta (Aβ) in brain. Mounting evidence has revealed critical roles of microRNAs (miRNAs) in AD pathogenesis; however, the miRNAs direc
Externí odkaz:
https://doaj.org/article/24f28c49a6ea467a97e6d589f80aa598