Zobrazeno 1 - 10
of 72
pro vyhledávání: '"SGTA"'
Autor:
Hill, J., Nyathi, Yvonne
Yes
Mislocalised membrane proteins (MLPs) present a risk to the cell due to exposed hydrophobic amino acids which cause MLPs to aggregate. Previous studies identified SGTA as a key component of the machinery that regulates the quality control of
Mislocalised membrane proteins (MLPs) present a risk to the cell due to exposed hydrophobic amino acids which cause MLPs to aggregate. Previous studies identified SGTA as a key component of the machinery that regulates the quality control of
Externí odkaz:
http://hdl.handle.net/10454/19112
Autor:
Shun Kubota, Hiroshi Doi, Shigeru Koyano, Kenichi Tanaka, Hiroyasu Komiya, Atsuko Katsumoto, Shingo Ikeda, Shunta Hashiguchi, Haruko Nakamura, Ryoko Fukai, Keita Takahashi, Misako Kunii, Mikiko Tada, Hideyuki Takeuchi, Fumiaki Tanaka
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-10 (2021)
Abstract Intracellular aggregates are a common pathological hallmark of neurodegenerative diseases such as polyglutamine (polyQ) diseases, amyotrophic lateral sclerosis (ALS), Parkinson’s disease (PD), and multiple system atrophy (MSA). Aggregates
Externí odkaz:
https://doaj.org/article/28ec26773d1e475c9691a8fbd146d1e6
Autor:
Yuiko Kato, Kazuhiko Ochiai, Shota Kawakami, Nobuhiro Nakao, Daigo Azakami, Makoto Bonkobara, Masaki Michishita, Masami Morimatsu, Masami Watanabe, Toshinori Omi
Publikováno v:
BMC Veterinary Research, Vol 13, Iss 1, Pp 1-8 (2017)
Abstract Background The pathological condition of canine prostate cancer resembles that of human androgen-independent prostate cancer. Both canine and human androgen receptor (AR) signalling are inhibited by overexpression of the dimerized co-chapero
Externí odkaz:
https://doaj.org/article/7bfc6b9ed9424551b996dc0b9dfa4eb8
Akademický článek
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Autor:
Kenichi Tanaka, Mikiko Tada, Shingo Ikeda, Hiroyasu Komiya, Ryoko Fukai, Shunta Hashiguchi, Haruko Nakamura, Keita Takahashi, Shun Kubota, Fumiaki Tanaka, Atsuko Katsumoto, Hideyuki Takeuchi, Shigeru Koyano, Hiroshi Doi, Misako Kunii
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-10 (2021)
Molecular Brain
Molecular Brain
Intracellular aggregates are a common pathological hallmark of neurodegenerative diseases such as polyglutamine (polyQ) diseases, amyotrophic lateral sclerosis (ALS), Parkinson’s disease (PD), and multiple system atrophy (MSA). Aggregates are mainl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21f19dd0ea57309a03c1fd3de23cff9
https://doaj.org/article/28ec26773d1e475c9691a8fbd146d1e6
https://doaj.org/article/28ec26773d1e475c9691a8fbd146d1e6
Autor:
Thapaliya, A., Nyathi, Yvonne, Martínez-Lumbreras, S., Krysztofinska, E.M., Evans, N.J., Terry, I.L., High, S., Isaacson, R.L.
Yes
The fate of secretory and membrane proteins that mislocalize to the cytosol is decided by a collaboration between cochaperone SGTA (small, glutamine-rich, tetratricopeptide repeat protein alpha) and the BAG6 complex, whose operation relies o
The fate of secretory and membrane proteins that mislocalize to the cytosol is decided by a collaboration between cochaperone SGTA (small, glutamine-rich, tetratricopeptide repeat protein alpha) and the BAG6 complex, whose operation relies o
Externí odkaz:
http://hdl.handle.net/10454/17893
Autor:
Fry, Michelle Yen
The successful biogenesis – synthesis, delivery, and insertion into designated membranes – of membrane proteins is a crucial cellular process. One particular class of membrane proteins, tail-anchored (TA) proteins have a single transmembrane doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e64450b65ff0aa4bfe790d66f1db266
Autor:
Joanna D Roberts, Arjun eThapaliya, Santiago eMartínez Lumbreras, Ewelina eKrysztofinska, Rivka Leah Isaacson
Publikováno v:
Frontiers in Molecular Biosciences, Vol 2 (2015)
SGTA is a co-chaperone that interacts with molecular chaperones and steroid receptor complexes and plays an important role in various cellular pathways. It consists of three structural domains with individual functions, an N-terminal dimerisation dom
Externí odkaz:
https://doaj.org/article/8c145617112f422fbbdb2514233f5935
Publikováno v:
The Journal of Biological Chemistry
The targeting and insertion of tail-anchored (TA) integral membrane proteins (IMPs) into the correct membrane is critical for cellular homeostasis. The fungal protein Sgt2, and its human homolog SGTA, is the entry point for clients to the guided entr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83ce878dc24df6e9c96eec46dad7f8f
https://pubmed.ncbi.nlm.nih.gov/33610544
https://pubmed.ncbi.nlm.nih.gov/33610544
Akademický článek
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