Associations of the systolic and diastolic components of orthostatic hypotension with markers of cardiovascular risk in older men: A cross-sectional analysis from The British Regional Heart Study

Autor: SG Wannamethee, Sheena E Ramsay, Peter H. Whincup, Olia Papacosta, Stephen P. Juraschek, Artaza Gilani, Lucy T. Lennon

Publikováno v: Journal of clinical hypertension (Greenwich, Conn.)

The mechanisms underlying the association between orthostatic hypotension (OH) and cardiovascular disease are unclear. We investigated whether OH is associated with circulating cardiovascular risk markers. This was a cross-sectional analysis of 3857

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c01b1c7968bebd9a36d457b6dd2280
http://europepmc.org/articles/PMC8029713

OP52 Association between cardiovascular health and stroke in older British men: findings from the british regional heart study

Autor: A Ahmed, SG Wannamethee, SM Pinto Pereira, Peter H. Whincup, Olia Papacosta, Lucy T. Lennon

Publikováno v: Oral Presentations.

Background The American Heart Association’s model of ideal cardiovascular health (CVH), based on 7 well-known and modifiable health factors (body mass index, blood pressure (BP), glucose, cholesterol, physical activity, smoking and diet - Life’s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3d4f21d15af76ad169b5da33ebc4604
https://doi.org/10.1136/jech-2020-ssmabstracts.51

Socioeconomic disadvantage across the life-course and oral health in older age: findings from a longitudinal study of older British men

Autor: Sheena E Ramsay, Efstathios Papachristou, Peter H. Whincup, Lucy T. Lennon, Richard G. Watt, SG Wannamethee, AO Papacosta

Publikováno v: Journal of Public Health. 40:e423-e430

Background: The influence of life-course socioeconomic disadvantage on oral health at older ages is not well-established. We examined the influence of socioeconomic factors in childhood, middle-age and older age on oral health at older ages, and test

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b04cc77c0237d5b0881c8e60130a06
https://doi.org/10.1093/pubmed/fdy068

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

Autor: Tina Shah, E. C. M. van Leeuwen, Jingjing Liang, Susan M. Ring, Alexander Teumer, P Anugu, Salman M. Tajuddin, Aaron Isaacs, Jorgen Engmann, Marcus Dörr, Kenneth Rice, Anne B. Newman, Sonia Shah, Lenore J. Launer, Diana Kuh, Panos Roussos, P. De Vries, Bo Hedblad, Xiaofeng Zhu, Walter Palmas, John E. Deanfield, Debbie A Lawlor, Ganesh Chauhan, Dennis O. Mook-Kanamori, André G. Uitterlinden, Sudha Seshadri, Ilja M. Nolte, Elmo Mannarino, Daniel H. O'Leary, Susan R. Heckbert, Bogdan Pasaniuc, Solomon K. Musani, Rebecca Hardy, Rainer Malik, Lesca M. Holdt, Lars Lind, Reinhold Schmidt, R. de Mutsert, Aroon D. Hingorani, Riccardo E. Marioni, P. Amouyel, Albert V. Smith, Janne Pott, Eric E. Schadt, Lyytikäinen L-P., Raymond Noordam, Stéphanie Debette, Oscar H. Franco, Vincent Plagnol, Gerardo Heiss, Brenda W.J.H. Penninx, SG Wannamethee, Carl D. Langefeld, Stella Trompet, C.M. van Duijn, Tessel E. Galesloot, Peter K. Joshi, Maryam Kavousi, Juan P. Casas, Joanna M. Wardlaw, P. Giral, Julian Halcox, Björkegren Jlm., U de Faire, Andries J. Smit, Christina L. Wassel, Christopher J. O'Donnell, Matthew Traylor, Uwe Völker, Mika Kivimäki, Jenna Price, Quenna Wong, Chris Finan, Wayne D. Rosamond, Markus Loeffler, Harry Campbell, L Lu, Jerome I. Rotter, Joop Jukema, Karl Gertow, Edith Hofer, Hugh S. Markus, Albert Hofman, Peter H. Whincup, James G. Wilson, Michelle K. Evans, Enzo Grossi, Matthias Sitzer, Martin Dichgans, Oscar L. Rueda-Ochoa, J. C. Bis, Klodian Dhana, Ralph Burkhardt, Harold Snieder, Kiemeney Lalm., Daniel Teupser, A C Morrison, Markus Scholz, Ulf Schminke, Richard W Morris, Meena Kumari, Caroline Dale, Helena Schmidt, Sara Hägg, Niina Pitkänen, Fabrizio Veglia, Donald W. Bowden, Olli T. Raitakari, Joachim Thiery, Anders Hamsten, Muralidharan Sargurupremraj, Hwang S-J., Elena Tremoli, Stela McLachlan, Amanda J. Cox, Kent D. Taylor, Frank Beutner, Henry Völzke, Terho Lehtimäki, Abbas Dehghan, Ruth C. Lovering, Rachael P. Huntley, Mike A. Nalls, Jemma C. Hopewell, Erik Ingelsson, Claudia Giambartolomei, Bruce M. Psaty, Annie Britton, A Seldenrijk, Bengt Sennblad, Olle Melander, J. de Graaf, Adolfo Correa, Fernando Rivadeneira, Oscar Franzén, Laura M. Raffield, Alan B. Zonderman, Rona J. Strawbridge, Thomas W. Winkler, Ian J. Deary, Misa Graff, Wendy S. Post, Andrew Wong, T.B. Harris, Yasaman Saba, Arno Ruusalepp, James F. Wilson, Vilmundur Gudnason, Eric Boerwinkle, Damiano Baldassarre, Cristiano Fava, S.E. Humphries, Sudhir Kurl, Rainer Rauramaa, Christophe Tzourio, Xuejiang Guo, Nora Franceschini, Xiaoling Zhang

Publikováno v: Nature Communications, 9:5141. Nature Publishing Group
Nature Communications, 9
Franceschini, N, Giambartolomei, C, De Vries, P S, Finan, C, Bis, J C, Huntley, R P, Lovering, R C, Tajuddin, S M, Winkler, T W, Graff, M, Kavousi, M, Dale, C, Smith, A V, Hofer, E, Van Leeuwen, E M, Nolte, I M, Lu, L, Scholz, M, Sargurupremraj, M, Pitkänen, N, Franzén, O, Joshi, P K, Noordam, R, Marioni, R E, Hwang, S, Musani, S K, Schminke, U, Palmas, W, Isaacs, A, Correa, A, Zonderman, A B, Hofman, A, Teumer, A, Cox, A J, Uitterlinden, A G, Wong, A, Smit, A J, Newman, A B, Britton, A, Ruusalepp, A, Sennblad, B, Hedblad, B, Pasaniuc, B, Penninx, B W, Langefeld, C D, Wassel, C L, Tzourio, C, Fava, C, Baldassarre, D, O’leary, D H, Teupser, D, Kuh, D, Tremoli, E, Mannarino, E, Grossi, E, Boerwinkle, E, Schadt, E E, Ingelsson, E, Veglia, F, Rivadeneira, F, Beutner, F, Chauhan, G, Heiss, G, Snieder, H, Campbell, H, Völzke, H, Markus, H S, Deary, I J, Jukema, J W, De Graaf, J, Price, J, Pott, J, Hopewell, J C, Liang, J, Thiery, J, Engmann, J, Gertow, K, Rice, K, Taylor, K D, Dhana, K, Kiemeney, L A L M, Lind, L, Raffield, L M, Launer, L J, Holdt, L M, Dörr, M, Dichgans, M, Traylor, M, Sitzer, M, Kumari, M, Kivimaki, M, Nalls, M A, Melander, O, Raitakari, O, Franco, O H, Rueda-ochoa, O L, Roussos, P, Whincup, P H, Amouyel, P, Giral, P, Anugu, P, Wong, Q, Malik, R, Rauramaa, R, Burkhardt, R, Hardy, R, Schmidt, R, De Mutsert, R, Morris, R W, Strawbridge, R J, Wannamethee, S G, Hägg, S, Shah, S, Mclachlan, S, Trompet, S, Seshadri, S, Kurl, S, Heckbert, S R, Ring, S, Harris, T B, Lehtimäki, T, Galesloot, T E, Shah, T, De Faire, U, Plagnol, V, Rosamond, W D, Post, W, Zhu, X, Zhang, X, Guo, X, Saba, Y, Dehghan, A, Seldenrijk, A, Morrison, A C, Hamsten, A, Psaty, B M, Van Duijn, C M, Lawlor, D A, Mook-kanamori, D O, Bowden, D W, Schmidt, H, Wilson, J G, Rotter, J I, Wardlaw, J M, Deanfield, J, Halcox, J, Lyytikäinen, L, Loeffler, M, Evans, M K, Debette, S, Humphries, S E, Völker, U, Gudnason, V, Hingorani, A D, Björkegren, J L M, Casas, J P & O’donnell, C J 2018, ' GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes ', Nature Communications, vol. 9, no. 1, 5141 . https://doi.org/10.1038/s41467-018-07340-5
Franceschini, Nora; Giambartolomei, Claudia; de Vries, Paul S; Finan, Chris; Bis, Joshua C; Huntley, Rachael P; Lovering, Ruth C; Tajuddin, Salman M; Winkler, Thomas W; Graff, Misa; Kavousi, Maryam; Dale, Caroline; Smith, Albert V; Hofer, Edith; van Leeuwen, Elisabeth M; Nolte, Ilja M; Lu, Lingyi; Scholz, Markus; Sargurupremraj, Muralidharan; Pitkänen, Niina; ... (2018). GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nature communications, 9(1), p. 5141. Nature Publishing Group 10.1038/s41467-018-07340-5
Giambartolomei, C, de Vries, P S, Finan, C, Bis, J C, Huntley, R P, Lovering, R C, Tajuddin, S M, Winkler, T W, Graff, M, Kavousi, M, Dale, C, Smith, A V, Hofer, E, van Leeuwen, E M, Nolte, I M, Lu, L, Scholz, M, Sargurupremraj, M, Pitkänen, N, Franzén, O, Joshi, P K, Noordam, R, Marioni, R E, Hwang, S-J, Musani, S K, Schminke, U, Palmas, W, Isaacs, A, Correa, A, Zonderman, A B, Hofman, A, Teumer, A, Cox, A J, Uitterlinden, A G, Wong, A, Smit, A J, Newman, A B, Britton, A, Ruusalepp, A, Sennblad, B, Hedblad, B, Pasaniuc, B, Kuh, D, Kumari, M, Kivimaki, M, Morris, R W, Ring, S & Wilson, J G & Deanfield, J 2018, ' GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes ', Nature Communications, vol. 9, 5141 . https://doi.org/10.1038/s41467-018-07340-5
Franceschini, N, Giambartolomei, C, de Vries, P S, Finan, C, Bis, J C, Huntley, R P, Lovering, R C, Tajuddin, S M, Winkler, T W, Graff, M, Kavousi, M, Dale, C, Smith, A V, Hofer, E, van Leeuwen, E M, Nolte, I M, Lu, L, Scholz, M, Sargurupremraj, M, Pitkänen, N, Franzén, O, Joshi, P K, Noordam, R, Marioni, R E, Hwang, S-J, Musani, S K, Schminke, U, Palmas, W, Isaacs, A, Correa, A, Zonderman, A B, Hofman, A, Teumer, A, Cox, A J, Uitterlinden, A G, Wong, A, Smit, A J, Newman, A B, Britton, A, Ruusalepp, A, Sennblad, B, Hedblad, B, Pasaniuc, B, Penninx, B W, Langefeld, C D, Wassel, C L, Tzourio, C, Adams, H H H, Seldenrijk, A, Adams, H H H & MEGASTROKE Consortium 2018, ' GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes ', Nature Communications, vol. 9, no. 1, 5141 . https://doi.org/10.1038/s41467-018-07340-5
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications, 9(1):5141. Nature Publishing Group
Franceschini, N, Giambartolomei, C, De Vries, P S, Finan, C, Bis, J C, Huntley, R P, Lovering, R C, Tajuddin, S M, Winkler, T W, Graff, M, Kavousi, M, Dale, C, Smith, A V, Hofer, E, Van Leeuwen, E M, Nolte, I M, Lu, L, Scholz, M, Sargurupremraj, M, Pitkänen, N, Franzén, O, Joshi, P K, Noordam, R, Marioni, R E, Hwang, S, Musani, S K, Schminke, U, Palmas, W, Isaacs, A, Correa, A, Zonderman, A B, Hofman, A, Teumer, A, Cox, A J, Uitterlinden, A G, Wong, A, Smit, A J, Newman, A B, Britton, A, Ruusalepp, A, Sennblad, B, Hedblad, B, Pasaniuc, B, Penninx, B W, Langefeld, C D, Wassel, C L, Tzourio, C, Fava, C, Baldassarre, D, O’leary, D H, Teupser, D, Kuh, D, Tremoli, E, Mannarino, E, Grossi, E, Boerwinkle, E, Schadt, E E, Ingelsson, E, Veglia, F, Rivadeneira, F, Beutner, F, Chauhan, G, Heiss, G, Snieder, H, Campbell, H, Völzke, H, Markus, H S, Deary, I J, Jukema, J W, De Graaf, J, Price, J, Pott, J, Hopewell, J C, Liang, J, Thiery, J, Engmann, J, Gertow, K, Rice, K, Taylor, K D, Dhana, K, Kiemeney, L A L M, Lind, L, Raffield, L M, Launer, L J, Holdt, L M, Dörr, M, Dichgans, M, Traylor, M, Sitzer, M, Kumari, M, Kivimaki, M, Nalls, M A, Melander, O, Raitakari, O, Franco, O H, Rueda-ochoa, O L, Roussos, P, Whincup, P H, Amouyel, P, Giral, P, Anugu, P, Wong, Q, Malik, R, Rauramaa, R, Burkhardt, R, Hardy, R, Schmidt, R, De Mutsert, R, Morris, R W, Strawbridge, R J, Wannamethee, S G, Hägg, S, Shah, S, Mclachlan, S, Trompet, S, Seshadri, S, Kurl, S, Heckbert, S R, Ring, S, Harris, T B, Lehtimäki, T, Galesloot, T E, Shah, T, De Faire, U, Plagnol, V, Rosamond, W D, Post, W, Zhu, X, Zhang, X, Guo, X, Saba, Y, Dehghan, A, Seldenrijk, A, Morrison, A C, Hamsten, A, Psaty, B M, Van Duijn, C M, Lawlor, D A, Mook-kanamori, D O, Bowden, D W, Schmidt, H, Wilson, J G, Wilson, J G, Rotter, J I, Wardlaw, J M, Deanfield, J, Halcox, J, Lyytikäinen, L, Loeffler, M, Evans, M K, Debette, S, Humphries, S E, Völker, U, Gudnason, V, Hingorani, A D, Björkegren, J L M, Casas, J P & O’donnell, C J 2018, ' GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes ' vol. 9, no. 1, 5141 . DOI: 10.1038/s41467-018-07340-5
Nature Communications
Nature communications, 9(1):5141. Nature Publishing Group

Publisher's version (útgefin grein)
Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosclerosis associated with ischemic stroke and coronary heart disease (CHD). Here, we undertake meta-analyses o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e74c44615367f516a16ae2ad5edfaa
https://cris.maastrichtuniversity.nl/en/publications/a7ac7ba6-ca45-4958-91f6-0a5296a2c6ac

OP24 Subclinical cardiovascular disease and frailty among british older men without a diagnosis of cardiovascular disease: a population-based study

Autor: Sheena E Ramsay, SG Wannamethee, Julian Halcox, Elizabeth A Ellins, Peter H. Whincup, M Patel, AO Papacosta, Lucy T. Lennon

Publikováno v: Oral presentations.

Background Frailty is associated with incident cardiovascular disease (CVD). However, its association with subclinical CVD, which precedes the onset of a CVD event, remains uncertain. Non-invasive vascular markers provide valuable proxy indicators of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b8e620724400abcf5206aaa479814fb
https://doi.org/10.1136/jech-2018-ssmabstracts.24