Zobrazeno 1 - 2
of 2
pro vyhledávání: '"SFX, serial femtosecond crystallography"'
Autor:
James Spencer, Catherine L. Tooke, Philip Hinchliffe, Yuiko Takebayashi, Viivi H. A. Hirvonen, Charlotte K. Colenso, Eilis C. Bragginton
Publikováno v:
Journal of Molecular Biology
Tooke, C, Hinchliffe, P, Bragginton, E, Colenso, C K, Hirvonen, V, Takebayashi, Y & Spencer, J 2019, ' β-Lactamases and β-Lactamase Inhibitors in the 21st Century ', Journal of Molecular Biology . https://doi.org/10.1016/j.jmb.2019.04.002
Tooke, C, Hinchliffe, P, Bragginton, E, Colenso, C K, Hirvonen, V, Takebayashi, Y & Spencer, J 2019, ' β-Lactamases and β-Lactamase Inhibitors in the 21st Century ', Journal of Molecular Biology . https://doi.org/10.1016/j.jmb.2019.04.002
The β-lactams retain a central place in the antibacterial armamentarium. In Gram-negative bacteria, β-lactamase enzymes that hydrolyze the amide bond of the four-membered β-lactam ring are the primary resistance mechanism, with multiple enzymes di
Autor:
George N. Phillips, Mitchell D. Miller
Publikováno v:
The Journal of Biological Chemistry
Proteins are the molecular machines of living systems. Their dynamics are an intrinsic part of their evolutionary selection in carrying out their biological functions. Although the dynamics are more difficult to observe than a static, average structu