The Microbiome Activates CD4 T-cell–mediated Immunity to Compensate for Increased Intestinal Permeability

Autor: Anne Sailer, Sarkis K. Mazmanian, Jerrold R. Turner, Karen L. Edelblum, Irene Thomsen, Chen Dong, Rima McLeod, Sarina Ravens, Matthew A. Odenwald, Gurminder Singh, Immo Prinz, Kamal El Bissati, Sandeep Gurbuxani, Severine Cao, Gil Sharon

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 2, Pp 285-297 (2017)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Despite a prominent association, chronic intestinal barrier loss is insufficient to induce disease in human subjects or experimental animals. We hypothesized that compensatory mucosal immune activation might protect individuals with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dffbd9a89ead44ab601abe9f6bc372a
https://doi.org/10.1016/j.jcmgh.2017.06.001

Host-Gut Microbiota Crosstalk in Intestinal Adaptation

Autor: Justine Marchix, Michael A. Helmrath, Gillian Goddard

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology

Short-bowel syndrome represents the most common cause of intestinal failure and occurs when the remaining intestine cannot support fluid and nutrient needs to sustain adequate physiology and development without the use of supplemental parenteral nutr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ecf09f7a4e623173c8f6856696496c3
https://pubmed.ncbi.nlm.nih.gov/30023411

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The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability.

Autor: Edelblum KL; Department of Pathology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.; Department of Pathology, University of Chicago, Chicago, Illinois., Sharon G; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California., Singh G; Department of Pathology, University of Chicago, Chicago, Illinois.; Departments of Pathology and Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Odenwald MA; Department of Pathology, University of Chicago, Chicago, Illinois., Sailer A; Department of Pathology, University of Chicago, Chicago, Illinois., Cao S; Department of Pathology, University of Chicago, Chicago, Illinois., Ravens S; Institute of Immunology, Hannover Medical School, Hannover, Germany., Thomsen I; Institute of Immunology, Hannover Medical School, Hannover, Germany., El Bissati K; Department of Ophthalmology and Visual Sciences, University of Chicago, Chicago, Illinois.; Department of Pediatrics, University of Chicago, Chicago, Illinois., McLeod R; Department of Ophthalmology and Visual Sciences, University of Chicago, Chicago, Illinois.; Department of Pediatrics, University of Chicago, Chicago, Illinois., Dong C; Institute for Immunology, Tsinghua University, Beijing, China., Gurbuxani S; Department of Pathology, University of Chicago, Chicago, Illinois., Prinz I; Institute of Immunology, Hannover Medical School, Hannover, Germany., Mazmanian SK; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California., Turner JR; Department of Pathology, University of Chicago, Chicago, Illinois.; Departments of Pathology and Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Publikováno v: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2017 Jun 10; Vol. 4 (2), pp. 285-297. Date of Electronic Publication: 2017 Jun 10 (Print Publication: 2017).

Control of commensal microbiota by the adaptive immune system.

Autor: Zhang H; a Department of Civil and Environmental Engineering ; Virginia Tech ; Blacksburg , VA USA., Luo XM

Publikováno v: Gut microbes [Gut Microbes] 2015; Vol. 6 (2), pp. 156-60.