Zobrazeno 1 - 10
of 657
pro vyhledávání: '"SETDB1"'
Autor:
Kang Xia, Yumin Hui, Long Zhang, Qiangmin Qiu, Jiacheng Zhong, Hui Chen, Xiuheng Liu, Lei Wang, Zhiyuan Chen
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background The role of histone methyltransferase SETDB1 in renal ischemia–reperfusion (I/R) injury has not been explored yet. This study aims to investigate the potential mechanism of SETDB1 in regulating renal I/R injury and its impact on
Externí odkaz:
https://doaj.org/article/4898b0484c62452598f3cdda867ed3a4
Autor:
Daijing Sun, Yueyan Zhu, Wenzhu Peng, Shenghui Zheng, Jie Weng, Shulong Dong, Jiaqi Li, Qi Chen, Chuanhui Ge, Liyong Liao, Yuhao Dong, Yun Liu, Weida Meng, Yan Jiang
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-27 (2024)
Abstract Background Transposable elements play a critical role in maintaining genome architecture during neurodevelopment. Short Interspersed Nuclear Elements (SINEs), a major subtype of transposable elements, are known to harbor binding sites for th
Externí odkaz:
https://doaj.org/article/1aa8d5c49c2d440086409983857309c8
Autor:
Enxiang Zhang, Pingping He
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Epigenetic alterations in gene expression have been implicated in cancer development and tumor immune escape, with posttranslational histone or non-histone modifications representing attractive targets for disease surveillance and therapy. SET domain
Externí odkaz:
https://doaj.org/article/e5e756c9cb45402599e92ad5315a1842
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 282, Iss , Pp 116686- (2024)
Constituents of cigarette smoke are known to be carcinogens. Additionally, there is mounting evidence that the liver is an organ susceptible to tobacco carcinogenicity. Nicotine, the primary constituent of tobacco, plays a role in cancer progression.
Externí odkaz:
https://doaj.org/article/fb1e089d330e40339d2ac3ce01432283
Autor:
Ming-Yan Shi, Yarong Wang, Ying Shi, Ruofei Tian, Xiaohong Chen, Hai Zhang, Ke Wang, Zhinan Chen, Ruo Chen
Publikováno v:
Genes and Diseases, Vol 11, Iss 2, Pp 978-992 (2024)
Protein post-translational modifications (PTMs) are at the heart status of cellular signaling events and broadly involved in tumor progression. CD147 is a tumor biomarker with various PTMs, promoting tumor metastasis and metabolism reprogramming. Nev
Externí odkaz:
https://doaj.org/article/90a5e3f6f56440e68d749566bfde9dcb
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background Ovarian cancer (OC) is the most lethal gynecologic malignant tumour. The mechanism promoting OC initiation and progression remains unclear. SET domain bifurcated histone lysine methyltransferase 1(SETDB1) acts as an oncogene in a
Externí odkaz:
https://doaj.org/article/95df38d8f83046e6a035bf5c92ae295e
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Histone methyltransferase SETDB1 (SET domain bifurcated histone lysine methyltransferase 1, also known as ESET or KMT1E) is known to be involved in the deposition of the di- and tri-methyl marks on H3K9 (H3K9me2 and H3K9me3), which are assoc
Externí odkaz:
https://doaj.org/article/6626538542614c6b9204535d4eadc4fb
Autor:
Pier-Angelo Tovo, Davide Giuseppe Ribaldone, Ilaria Galliano, Gian Paolo Caviglia, Maddalena Dini, Valentina Veglio, Cristina Calvi, Paola Montanari, Demis Pitoni, Simone Frara, Elisa Tribocco, Anxhela Poshnjari, Massimiliano Bergallo
Publikováno v:
Viruses, Vol 16, Iss 10, p 1570 (2024)
Inflammatory bowel disease (IBD) includes patients affected by Crohn’s disease or ulcerative colitis. IBD is thought to be a chronic immune-mediated disease, but its origin remains elusive, and this limits new therapeutic approaches. Human endogeno
Externí odkaz:
https://doaj.org/article/2d56ef8721f348c59b373e67df5f8601
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Autor:
Zidong Liu, Xiaoxu Chen, Pengfei Zhang, Fuyuan Li, Lingkai Zhang, Xueliang Li, Tao Huang, Yi Zheng, Taiyong Yu, Tao Zhang, Wenxian Zeng, Hongzhao Lu, Yinghua Lv
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 4, Pp 729-741 (2023)
Spermatogenesis is a continual process that occurs in the testes, in which diploid spermatogonial stem cells (SSCs) differentiate and generate haploid spermatozoa. This highly efficient and intricate process is orchestrated at multiple levels. N6-met
Externí odkaz:
https://doaj.org/article/cfb18b0a3a7b4ce0b48c1d881029d495