Exerting DNA Damaging Effects of the Ilimaquinones through the Active Hydroquinone Species

Autor: Apisada Jiso, Laphatrada Yurasakpong, Sirorat Janta, Kulathida Chaithirayanon, Anuchit Plubrukarn

Publikováno v: Scientia Pharmaceutica, Vol 89, Iss 2, p 26 (2021)

Possessing the quinone moiety, ilimaquinone (1), a sponge–derived sesquiterpene quinone, has been hypothesised to express its cytotoxicity through a redox cycling process, yielding active product(s) that can cause DNA damage. To determine the DNA d

Externí odkaz: https://doaj.org/article/30b2a0b5355b425284d9ffb036245082

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

The Role of Spongia sp. in the Discovery of Marine Lead Compounds

Autor: Patrícia Máximo, Luísa M. Ferreira, Paula Branco, Pedro Lima, Ana Lourenço

Publikováno v: Marine Drugs, Vol 14, Iss 8, p 139 (2016)

A comprehensive review on the chemistry of Spongia sp. is here presented, together with the biological activity of the isolated compounds. The compounds are grouped in sesquiterpene quinones, diterpenes, C21 and other linear furanoterpenes, sesterter

Externí odkaz: https://doaj.org/article/9a7b8efe783a494ba8a705e84d3b6931

Exerting DNA Damaging Effects of the Ilimaquinones through the Active Hydroquinone Species

Autor: Laphatrada Yurasakpong, Apisada Jiso, Sirorat Janta, Kulathida Chaithirayanon, Anuchit Plubrukarn

Publikováno v: Scientia Pharmaceutica
Volume 89
Issue 2
Scientia Pharmaceutica, Vol 89, Iss 26, p 26 (2021)

Possessing the quinone moiety, ilimaquinone (1), a sponge–derived sesquiterpene quinone, has been hypothesised to express its cytotoxicity through a redox cycling process, yielding active product(s) that can cause DNA damage. To determine the DNA d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9660f35e73928c626a8741e703fb72c1
https://doi.org/10.3390/scipharm89020026

A ring-distortion strategy from marine natural product ilimaquinone leads to quorum sensing modulators

Autor: Evanno, Laurent, Lachkar, David, Lamali, Assia, Boufridi, Asmaa, Seon-Meniel, Blandine, Tintillier, Florent, Saulnier, Denis, Denis, Stephanie, Genta-Jouve, Grégory, Jullian, Jean-Christophe, Leblanc, Karine, Beniddir, Mehdi A., Petek, Sylvain, Debitus, Cécile, Poupon, Erwan

Publikováno v: European Journal of Organic Chemistry
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2018, 2018 (20-21), pp.2486-2497. ⟨10.1002/ejoc.201800047⟩

WOS:000434220200016; International audience; We report herein a ring-distortion strategy applied to marine natural substances ilimaquinone and 5-epi-ilimaquinone. A chemically diverse library of molecules was synthesised that included rearrangements

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5ac976e212d53d3af77819d2df4b11e4
http://www.documentation.ird.fr/hor/fdi:010073101