Výsledky vyhledávání - "SERPINE1 Gene"

Akademický článek

Genotypic Frequencies of Mutations Associated with Alpha-1 Antitrypsin Deficiency in Unrelated Bone Marrow Donors from the Murcia Region Donor Registry in the Southeast of Spain

Autor: Irene Cuenca, Carmen Botella, María Rosa Moya-Quiles, Víctor Jimenez-Coll, José Antonio Galian, Helios Martinez-Banaclocha, Manuel Muro-Pérez, Alfredo Minguela, Isabel Legaz, Manuel Muro

Publikováno v: Diagnostics, Vol 13, Iss 17, p 2845 (2023)

Alpha-1 antitrypsin (AAT1) deficiency (AAT1D) is an inherited disease with an increased risk of chronic obstructive pulmonary disease (COPD), liver disease, and skin and blood vessel problems. AAT1D is caused by mutations in the SERPINE1 gene (Serine

Externí odkaz: https://doaj.org/article/e3f9a5232f9947f3a3e7c6fdf6775c20

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Akademický článek

Polymorphisms of Genes Involved in Endothelial Dysfunction in the Yakuts with COPD and Metabolic Syndrome

Autor: Ekaterina Borisova, Elena Kylbanova, Alexandra Asekritova, Nadezhda Maksimova, Varvara Neustroeva, Ulyana Portnyagina, Ara Donskaya

Publikováno v: International Journal of Biomedicine, Vol 8, Iss 2, Pp 134-138 (2018)

The aim of our research was to study the association of the -675 4G/5G (rs1799889) SNP of the SERPINE1 (PAI-1) gene and the Arg353Gln G>A (rs6046) SNP of the F7 gene with metabolic syndrome (MetS) in the Yakuts with COPD. Methods and Results: A mole

Externí odkaz: https://doaj.org/article/6766e5ce1380406e93d05ce771343e21

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Akademický článek

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Research Progress on the SERPINE1 Protein and Chronic Inflammatory Diseases of the Upper Respiratory Tract: A Literature Review

Autor: Shu-Ting Liang, Dan Li, Min Zhou, Cai-Shan Fang, Yan Yan, Teng-Yu Chen, Si-Min Wang, Yan Ruan, Man-Qing Lin

Publikováno v: International Archives of Allergy and Immunology. 182:1097-1102

SERPINE1 protein is one important member of the serine proteinase inhibitor E superfamily that plays a crucial role in the fibrinolytic system. It has been identified which is related to chronic inflammatory lung diseases like allergic asthma and lun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419bc6fc23f7774031cdcbb26e0633a0
https://doi.org/10.1159/000516195

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Polymorphisms of Genes Involved in Endothelial Dysfunction in the Yakuts with COPD and Metabolic Syndrome

Autor: Varvara Neustroeva, Ara Donskaya, Ekaterina Borisova, Ulyana Portnyagina, Nadezhda E. Maksimova, Alexandra Asekritova, Elena Kylbanova

Publikováno v: International Journal of Biomedicine, Vol 8, Iss 2, Pp 134-138 (2018)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d1092a9255151c54bec7319620701b
http://ijbm.org/articles/IJBM_8(2)_OA5.pdf

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Relationship between plasminogen activator inhibitor-1 gene alterations and fibrosis in peritoneal dialysis patients

Autor: Taner Camsari, Duygu Onur Cura, Ayfer Ülgenalp, Esra Ataman, Derya Erçal, Sibel Ersan, Serkan Yildiz, Mehmet Tanrisev

Publikováno v: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis TherapyREFERENCES. 25(1)

Peritoneal fibrosis (PF) is a pathological change that occurs mostly long-term peritoneal dialysis (PD) patients, as a result of triggering the inflammatory response. Plasminogen activator inhibitor-1 (PAI-1) is an important molecule featured in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d6be826e6fd24c3a84972e011462d6
https://pubmed.ncbi.nlm.nih.gov/32301223

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Haplotype analysis of SERPINE1 gene: Risk for aneurysmal subarachnoid hemorrhage and clinical outcomes

Autor: Philipp Hendrix, Robert H. Lipsky, Mali Mathru, Christoph J. Griessenauer, Winfield S. Fisher, R. Shane Tubbs, Mohammadali Mohajel Shoja, Nilesh A. Vyas, Jean-Francois Pittet, Robert M. Starke, Mark R. Harrigan, Mingkuan Lin, Paul M. Foreman, Beverly C. Walters

Publikováno v: Molecular Genetics & Genomic Medicine, Vol 7, Iss 8, Pp n/a-n/a (2019)
Molecular Genetics & Genomic Medicine

Background Aneurysmal subarachnoid hemorrhage (aSAH) has high fatality and permanent disability rates due to the severe damage to brain cells and inflammation. The SERPINE1 gene that encodes PAI‐1 for the regulation of tissue plasminogen activator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c6c9f938715934f10570a2be3c3617
https://doi.org/10.1002/mgg3.737

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Akademický článek

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Circulating Levels of PAI-1 and SERPINE1 4G/4G Polymorphism Are Predictive of Poor Prognosis in HCC Patients Undergoing TACE

Autor: Giancarlo Sciortino, Antonella Daniele, Ines Abbate, Carlo Sabbà, Antonio Mazzocca, Rosa Divella, Vito Michele Fazio, Gennaro Gadaleta-Caldarola, Porzia Casamassima, Eufemia Savino, Cosimo Gadaleta, Giovanni Simone

Publikováno v: Translational Oncology, Vol 8, Iss 4, Pp 273-278 (2015)

Although several molecular markers have been proposed as prognostic of disease progression in Hepatocellular carcinoma (HCC), predictive markers of response to treatment are still unsatisfactory. Here, we propose a genetic polymorphism as a potential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270be04697144837cc055fd8de269e98
http://www.sciencedirect.com/science/article/pii/S193652331500042X

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