Zobrazeno 1 - 10
of 203
pro vyhledávání: '"SEOK-HO KIM"'
Autor:
Su Hwan Park, Jin-Sung Ju, Hyunmin Woo, Hye Jin Yun, Su Bin Lee, Seok-Ho Kim, Balázs Győrffy, Eun-jeong Kim, Ho Kim, Hee Dong Han, Seong-il Eyun, Jong-Ho Lee, Yun-Yong Park
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 6, Pp 1373-1387 (2024)
Abstract N 6-adenosine methylation (m6A) is critical for controlling cancer cell growth and tumorigenesis. However, the function and detailed mechanism of how m6A methyltransferases modulate m6A levels on specific targets remain unknown. In the curre
Externí odkaz:
https://doaj.org/article/fcd9ea4a755d49499aa417748d2b3e11
Autor:
Hye Jin Yun, Min Li, Dong Guo, So Mi Jeon, Su Hwan Park, Je Sun Lim, Su Bin Lee, Rui Liu, Linyong Du, Seok-Ho Kim, Tae Hwan Shin, Seong-il Eyun, Yun-Yong Park, Zhimin Lu, Jong-Ho Lee
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-22 (2023)
Abstract Background Cancer cells undergo cellular adaptation through metabolic reprogramming to sustain survival and rapid growth under various stress conditions. However, how brain tumors modulate their metabolic flexibility in the naturally serine/
Externí odkaz:
https://doaj.org/article/86fd5a1bd9de41acb5b01536a204b8d7
Publikováno v:
Applied Biological Chemistry, Vol 66, Iss 1, Pp 1-8 (2023)
Abstract In current study, we addressed the anti-cancer effect of oleifolioside A and its mechanism on the regulation of cell death in HCT-116 human colorectal cancer cells. Oleifolioside A inhibited HCT-116 cell proliferation and caused apoptosis as
Externí odkaz:
https://doaj.org/article/a9d78f0fa78940c0896d3073055e7f3a
Publikováno v:
치위생과학회지, Vol 22, Iss 4, Pp 249-255 (2022)
Background: Sexual dimorphism is important for sex determination in the field of forensics. However, sexual dimorphism is commonly assessed using cone beam computed tomography (CBCT) rather than three-dimensional (3D) modeling software; therefore, st
Externí odkaz:
https://doaj.org/article/2e570f64e97e45a09560612fb13518e5
Autor:
In-Young Chung, Hye-Jeong Jang, Yeon-Ji Yoo, Joonseong Hur, Hyo-Young Oh, Seok-Ho Kim, You-Hee Cho
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 149-159 (2022)
Artemisinin (ARS) and its semi-synthetic derivatives are effective drugs to treat malaria and possess multiple therapeutic activities based on their endoperoxide bridge. Here, we showed that ARS displayed antibacterial efficacy in Drosophila systemic
Externí odkaz:
https://doaj.org/article/47fce97f62bf4d1faabfd776a8a58a7a
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Quinazolines are a class of nitrogen-containing heterocyclic compounds with broad-spectrum of pharmacological activities. Transition-metal-catalyzed reactions have emerged as reliable and indispensable tools for the synthesis of pharmaceuticals. Thes
Externí odkaz:
https://doaj.org/article/cb5a8c3a1e5e4912a250d432f13ee65d
Autor:
Hyun Su Kim, Hyejin Kong, Taewoo Kim, Changjin Lim, Seungbeom Lee, Seok-Ho Kim, Young-Ger Suh
Publikováno v:
Marine Drugs, Vol 21, Iss 5, p 281 (2023)
This study aimed to elucidate the structural congeners of natural izenamides A, B, and C (1–3) responsible for cathepsin D (CTSD) inhibition. Structurally modified izenamides were synthesized and biologically evaluated, and their biologically impor
Externí odkaz:
https://doaj.org/article/3d0321274dbe4b529d34a2e1c2d6eb62
Publikováno v:
Applied Sciences, Vol 13, Iss 2, p 1083 (2023)
Vibration of manufacturing machine parts can be reduced by applying CFRP to precision machines. Recently, the use of 3D printers in manufacturing has increased. However, there are few studies on the vibration characteristics of 3D printed composite m
Externí odkaz:
https://doaj.org/article/602e3fd05d12490c938a1e5b4380929f
Autor:
Sun-Mi Yun, Young-Min Han, Moon-Young Song, Da-Young Lee, Hyun Su Kim, Seok-Ho Kim, Eun-Hee Kim
Publikováno v:
Nutrients, Vol 15, Iss 1, p 99 (2022)
Fibrosis has various biological processes and affects almost every organ, especially in patients with inflammatory bowel disease, including Crohn’s disease, who experience discomfort caused by intestinal fibrosis, which is a problem that needs to b
Externí odkaz:
https://doaj.org/article/40143f31b9cc41bca1fc7de3ee12479a
Publikováno v:
Molecules, Vol 27, Iss 19, p 6660 (2022)
This paper reports a concise and scalable method for the synthesis of the phytoestrogen 7,2′-dihydroxy-4′,5′-dimethoxyisoflavanone 1 via an optimized synthetic route. Compound 1 was readily obtained in 11 steps and 11% overall yield on a gram s
Externí odkaz:
https://doaj.org/article/b26aabdcb1c14d4a95c86b0a8f64e094