Zobrazeno 1 - 10
of 1 349
pro vyhledávání: '"SEIZURE SUSCEPTIBILITY"'
Autor:
Jianyu Huang, Chongyang Sun, Qian Zhu, Ge Wu, Yi Cao, Jiarui Shi, Shuyu He, Luyao Jiang, Jianxiang Liao, Lin Li, Cheng Zhong, Yi Lu
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106637- (2024)
Pathogenic missense mutation of the FGF12 gene is responsible for a variable disease phenotypic spectrum. Disease-specific therapies require precise dissection of the relationship between different mutations and phenotypes. The lack of a proper anima
Externí odkaz:
https://doaj.org/article/d080433cf9324585b184c419094b9905
Autor:
Shangnan Zou, Yinchao Li, Qihang Zou, Man Yang, Huifeng Li, Ruili Niu, Huanling Lai, Jiaoyang Wang, Xiaofeng Yang, Liemin Zhou
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionThe gut microbiota and the microbiota-gut-brain axis have gained considerable attention in recent years, emerging as key players in the mechanisms that mediate the occurrence and progression of many central nervous system-related diseases
Externí odkaz:
https://doaj.org/article/5f35e5c8097444bda673bcd1d06cf692
Autor:
Jennifer C. Wong, Andrew Escayg
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Patients with mutations that alter the function of the sodium channel SCN8A present with a range of clinical features, including mild to severe seizures, developmental delay, intellectual disability, autism, feeding dysfunction, motor impairment, and
Externí odkaz:
https://doaj.org/article/68547764bfb74cd881ccd8a65e1fefe2
Autor:
Bárbara Costa, Nuno Vale
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3730 (2024)
The intricate relationship between viruses and epilepsy involves a bidirectional interaction. Certain viruses can induce epilepsy by infecting the brain, leading to inflammation, damage, or abnormal electrical activity. Conversely, epilepsy patients
Externí odkaz:
https://doaj.org/article/2acffc65970c428aa16156a7bdd96894
Akademický článek
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Autor:
Wan-Yu Huang, Yen-Ling Lai, Ko-Hung Liu, Shankung Lin, Hsuan-Ying Chen, Chih-Hung Liang, Hung-Ming Wu, Kuei-Sen Hsu
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Systemic inflammation is a potent contributor to increased seizure susceptibility. However, information regarding the effects of systemic inflammation on cerebral vascular integrity that influence neuron excitability is scarce. Ne
Externí odkaz:
https://doaj.org/article/dfb6936973e349f3acd45a3db7f0332c
Autor:
Yoneko Hayase, Shigeru Amano, Koichi Hashizume, Takashi Tominaga, Hiroyuki Miyamoto, Yukie Kanno, Yukiko Ueno-Inoue, Takayoshi Inoue, Mayumi Yamada, Shigehiro Ogata, Shabeesh Balan, Ken Hayashi, Yoshiki Miura, Kentaro Tokudome, Yukihiro Ohno, Takuma Nishijo, Toshihiko Momiyama, Yuchio Yanagawa, Akiko Takizawa, Tomoji Mashimo, Tadao Serikawa, Akihiro Sekine, Eiji Nakagawa, Eri Takeshita, Takeo Yoshikawa, Chikako Waga, Ken Inoue, Yu-ichi Goto, Yoichi Nabeshima, Nobuo Ihara, Kazuhiro Yamakawa, Shinichiro Taya, Mikio Hoshino
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract The Ihara epileptic rat (IER) is a mutant model with limbic-like seizures whose pathology and causative gene remain elusive. In this report, via linkage analysis, we identified Down syndrome cell adhesion molecule-like 1(Dscaml1) as the resp
Externí odkaz:
https://doaj.org/article/83b2c846e60840adb9d55f24ef0bdf26
Autor:
Ricardo Mario Arida, Adrielle Andrade Passos, Alexandre Lebedev Graciani, João Angelo Ferres Brogin, Mayara de Almeida Lima Ribeiro, Jean Faber, Robson Campos Gutierre, Lavinia Teixeira-Machado
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background: Clinical and pre-clinical studies indicate a reduction in seizure frequency as well as a decrease in susceptibility to subsequently evoked seizures after physical exercise programs. In contrast to the influence of exercise after epilepsy
Externí odkaz:
https://doaj.org/article/fddc4b69312543a3bca15144c5823eb2
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
A large body of data has confirmed that α7 nicotinic acetylcholine receptors (nAChRs) play a pivotal role in cognition, memory, and other neuropsychiatric diseases, but their effect on seizure susceptibility in C57BL/6 wild-type mice is not fully un
Externí odkaz:
https://doaj.org/article/bba2b741723b4841a0bddcff638dbc4a
Akademický článek
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