Zobrazeno 1 - 10
of 83
pro vyhledávání: '"SEIICHI MAWATARI"'
Autor:
Ai Toyodome, Seiichi Mawatari, Hiromi Eguchi, Midori Takeda, Kotaro Kumagai, Ohki Taniyama, Sho Ijuin, Haruka Sakae, Kazuaki Tabu, Kohei Oda, Masanori Ikeda, Akio Ido
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Resistance-associated substitutions (RASs) of hepatitis C virus (HCV) affect the efficacy of direct-acting antivirals (DAAs). In this study, we aimed to clarify the susceptibility of the coexistence of nonstructural (NS) 5A Q24K/L28M/R30Q (o
Externí odkaz:
https://doaj.org/article/3fe6eb0227284a16be2ea8103fd1f582
Autor:
Shin Kawasoe, Takuro Kubozono, Anwar Ahmed Salim, Haruhito Yoshimine, Seiichi Mawatari, Satoko Ojima, Takeko Kawabata, Yoshiyuki Ikeda, Hironori Miyahara, Koichi Tokushige, Akio Ido, Mitsuru Ohishi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Chronic kidney disease (CKD) is a risk factor for end-stage renal disease and contributes to increased risk of cardiovascular disease morbidity and mortality. We aimed to develop a risk prediction score and equation for future CKD using heal
Externí odkaz:
https://doaj.org/article/c80e6591e345405dbee6e4918e3322b9
Autor:
Kotaro Kumagai, Shuji Kanmura, Seiichi Mawatari, Yuko Nakamura, Hiromi Eguchi, Oki Taniyama, Ai Toyodome, Sho Ijuin, Haruka Sakae, Kazuaki Tabu, Kohei Oda, Keita Shimata, Taizo Hibi, Akio Ido
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: Glycoprotein non-metastatic melanoma protein B (GPNMB) is expressed in macrophages during recovery from acute liver injury (ALI) in carbon tetrachloride (CCl4)-induced liver injury model mice. In this retrospective study, we assessed whet
Externí odkaz:
https://doaj.org/article/a1f40279821e4041848a49127e33c2db
Autor:
Masahito Nakano, Hiroshi Yatsuhashi, Shigemune Bekki, Yuko Takami, Yasuhito Tanaka, Yoko Yoshimaru, Koichi Honda, Yasuji Komorizono, Masaru Harada, Michihiko Shibata, Shotaro Sakisaka, Satoshi Shakado, Kenji Nagata, Tomoharu Yoshizumi, Shinji Itoh, Tetsuro Sohda, Satoshi Oeda, Kazuhiko Nakao, Ryu Sasaki, Tsutomu Yamashita, Akio Ido, Seiichi Mawatari, Makoto Nakamuta, Yoshifusa Aratake, Shuichi Matsumoto, Tatsuji Maeshiro, Takashi Goto, Takuji Torimura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-6 (2022)
Abstract We examined the epidemiological trends, including the distribution of sex, age, and disease etiology, in HCC incident cases, over 24 years. Data of 20,547 HCC patients (1996–2019) were analyzed in this prospective study. We divided the stu
Externí odkaz:
https://doaj.org/article/ba08a440e8c64ebab6c68403cc64c377
Autor:
Seiichi Mawatari, Kotaro Kumagai, Kohei Oda, Kazuaki Tabu, Sho Ijuin, Kunio Fujisaki, Shuzo Tashima, Yukiko Inada, Hirofumi Uto, Akiko Saisyoji, Yasunari Hiramine, Masafumi Hashiguchi, Tsutomu Tamai, Takeshi Hori, Ohki Taniyama, Ai Toyodome, Haruka Sakae, Takeshi Kure, Kazuhiro Sakurai, Akihiro Moriuchi, Shuji Kanmura, Akio Ido
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
Background The features of hepatitis C virus patients with a sustained virologic response (SVR) who developed hepatocellular carcinoma (HCC) after direct-acting antiviral (DAA) therapy are unclear. Methods The study population included 1494 DAA-SVR p
Externí odkaz:
https://doaj.org/article/a9d631c3572b48d2b03ea489655c1018
Autor:
Masahito Nakano, Hironori Koga, Tatsuya Ide, Ryoko Kuromatsu, Satoru Hashimoto, Hiroshi Yatsuhashi, Masataka Seike, Nobito Higuchi, Makoto Nakamuta, Satoshi Shakado, Shotaro Sakisaka, Satoshi Miuma, Kazuhiko Nakao, Yoko Yoshimaru, Yutaka Sasaki, Satoshi Oeda, Yuichiro Eguchi, Yuichi Honma, Masaru Harada, Kenji Nagata, Seiichi Mawatari, Akio Ido, Tatsuji Maeshiro, Shuichi Matsumoto, Yuko Takami, Tetsuo Sohda, Takuji Torimura
Publikováno v:
Cancer Medicine, Vol 8, Iss 5, Pp 2646-2653 (2019)
Abstract Background Previous studies have suggested an association between the use of direct‐acting antiviral agents (DAAs) for treating hepatitis C virus (HCV) infection and the resulting decrease in the incidence of hepatocellular carcinoma (HCC)
Externí odkaz:
https://doaj.org/article/1e69a258c4b74eb6a2d490773bf0ca2a
Autor:
Nao Nishikoba, Kotaro Kumagai, Shuji Kanmura, Yuko Nakamura, Mayumi Ono, Hiromi Eguchi, Tomomi Kamibayashiyama, Kohei Oda, Seiichi Mawatari, Shiroh Tanoue, Shinichi Hashimoto, Hirohito Tsubouchi, Akio Ido
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Backgrounds and Aims: Hepatocyte Growth Factor (HGF)-MET signaling is known to promote biological functions such as cell survival, cell motility, and cell proliferation. However, it is unknown if HGF-MET alters the macrophage phenotype. In this study
Externí odkaz:
https://doaj.org/article/45c402f89fa444ca809e820f37cca1ab
Autor:
Kazuaki Tabu, Seiichi Mawatari, Kohei Oda, Kotaro Kumagai, Yukiko Inada, Hirofumi Uto, Akiko Saisyoji, Yasunari Hiramine, Masafumi Hashiguchi, Tsutomu Tamai, Takeshi Hori, Kunio Fujisaki, Dai Imanaka, Takeshi Kure, Ohki Taniyama, Ai Toyodome, Sho Ijuin, Haruka Sakae, Kazuhiro Sakurai, Akihiro Moriuchi, Shuji Kanmura, Akio Ido
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237475 (2020)
Background and aimsDirect-acting antivirals (DAAs) against hepatitis C virus (HCV) exert high anti-HCV activity and are expected to show anti-inflammatory effects associated with HCV elimination. Furthermore, hepatocellular carcinoma (HCC) is known t
Externí odkaz:
https://doaj.org/article/77e19cc7fd2f44569864b15ba39951ef
Autor:
Nobuhiro Hiraishi, Shuji Kanmura, Kouhei Oda, Shiho Arima, Kotaro Kumagai, Seiichi Mawatari, Shiroh Tanoue, Fumisato Sasaki, Shinichi Hashimoto, Akio Ido
Publikováno v:
Biochemistry and Biophysics Reports, Vol 20, Iss , Pp - (2019)
Colorectal cancer is a multi-factorial disease involving genetic, environmental and lifestyle risk factors. In recent years, many changes in the bacterial composition of the intestinal microflora have been reported in colorectal cancer, suggesting th
Externí odkaz:
https://doaj.org/article/fc6ca359adb6438696cab75cb38cfc7b
Autor:
Seiichi Mawatari, Kohei Oda, Kazuaki Tabu, Sho Ijuin, Kotaro Kumagai, Kunio Fujisaki, Masafumi Hashiguchi, Yukiko Inada, Hirofumi Uto, Yasunari Hiramine, Takeshi Kure, Takeshi Hori, Oki Taniyama, Ai Kasai, Tsutomu Tamai, Akihiro Moriuchi, Akio Ido
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198642 (2018)
OBJECTIVE:The present study aimed to reveal the factors associated with virologic failure in sofosbuvir and ledipasvir (SOF/LDV)-treated patients, and identify baseline NS5A or NS5B resistance-associated substitutions (RASs). METHODS:Four hundred nin
Externí odkaz:
https://doaj.org/article/dd5b56e94e8f4b56a63aad408af02b30