Zobrazeno 1 - 10
of 2 722
pro vyhledávání: '"SECRETORY IGA"'
Autor:
Viraj Mane, Rikin Mehta, Nadine Alvarez, Vijeta Sharma, Steven Park, Alisa Fox, Claire DeCarlo, Xiaoqi Yang, David S. Perlin, Rebecca L. R. Powell
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTImmunoglobulin A (IgA) is the most abundant antibody (Ab) in human mucosae, with secretory form (sIgA) being dominant and uniquely stable. sIgA is challenging to produce recombinantly but is naturally found in human milk, which could be consi
Externí odkaz:
https://doaj.org/article/153200af89144a789b7529410b461fc2
Autor:
Madison L. Seefeld, Erin L. Templeton, Justin M. Lehtinen, Noah Sinclair, Daman Yadav, Brittany L. Hartwell
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Mucosal barrier tissues and their mucosal associated lymphoid tissues (MALT) are attractive targets for vaccines and immunotherapies due to their roles in both priming and regulating adaptive immune responses. The upper and lower respiratory mucosae,
Externí odkaz:
https://doaj.org/article/24586b0172c041f29ccbf09d25a7d562
Autor:
Erbs, Gitte a, Jakobsen, Jeanne Toft a, Schmidt, Signe Tandrup a, Christensen, Dennis a, Bailey, Mick b, Jungersen, Gregers a, ⁎
Publikováno v:
In Vaccine 6 February 2025 46
Autor:
Min Ja Lee, Seokwon Shin, Hyeong Won Kim, Mi-Kyeong Ko, So Hui Park, Su-Mi Kim, Jong-Hyeon Park
Publikováno v:
Vaccines, Vol 12, Iss 11, p 1268 (2024)
Background/Objectives: Foot-and-mouth disease (FMD) remains a significant global threat to livestock farming. Current commercial FMD vaccines present several challenges, including the risk of infection and adverse injection site reactions due to oil-
Externí odkaz:
https://doaj.org/article/6ff62d9e55764336a748cb351c3abc6a
Autor:
Baoqing Sun, Zhilong Chen, Bo Feng, Si Chen, Shilin Feng, Qian Wang, Xuefeng Niu, Zhengyuan Zhang, Peiyan Zheng, Ming Lin, Jia Luo, Yingxian Pan, Suhua Guan, Nanshan Zhong, Ling Chen
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionInfection with SARS-CoV-2 begins in the upper respiratory tract and can trigger the production of mucosal spike-specific secretory IgA (sIgA), which provides protection against reinfection. It has been recognized that individuals with hig
Externí odkaz:
https://doaj.org/article/42de5a24b6c244da991d5246385c20e9
Autor:
Rob van Dalen, Ahmed M. A. Elsherbini, Mareike Harms, Svenja Alber, Regine Stemmler, Andreas Peschel
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract Background Respiratory mucosal host defense relies on the production of secretory IgA (sIgA) antibodies, but we currently lack a fundamental understanding of how sIgA is induced by contact with microbes and how such immune responses may vary
Externí odkaz:
https://doaj.org/article/26f0067530e34ac89285dc85d3ed28e4
Autor:
Oscar Bladh, Katherina Aguilera, Ulrika Marking, Martha Kihlgren, Nina Greilert Norin, Anna Smed-Sörensen, Margaret Sällberg Chen, Jonas Klingström, Kim Blom, Michael W. Russell, Sebastian Havervall, Charlotte Thålin, Mikael Åberg
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSeveral novel vaccine platforms aim at mucosal immunity in the respiratory tract to block SARS-CoV-2 transmission. Standardized methods for mucosal sample collection and quantification of mucosal antibodies are therefore urgently needed f
Externí odkaz:
https://doaj.org/article/a59bbfa69e1c41f9b56f87eee6cfdce7
Publikováno v:
Vaccines, Vol 12, Iss 6, p 572 (2024)
Oral vaccines, unlike injected, induce intestinal secretory immunoglobulin A (sIgA) mimicking our natural defense against gut pathogens. We previously observed sIgA responses after administering the Clostridioides difficile colonisation factor CD0873
Externí odkaz:
https://doaj.org/article/c56aef2ce4dd46f9b1cba496a0b0315c
Autor:
Jason S. Chwa, Minjun Kim, Yesun Lee, Wesley A. Cheng, Yunho Shin, Jaycee Jumarang, Jeffrey M. Bender, Pia S. Pannaraj
Publikováno v:
Viruses, Vol 16, Iss 6, p 852 (2024)
Mucosal immunity may contribute to clearing SARS-CoV-2 infection prior to systemic infection, thereby allowing hosts to remain seronegative. We describe the meaningful detection of SARS-CoV-2-specific nasal mucosal antibodies in a group of exposed-ho
Externí odkaz:
https://doaj.org/article/83d7380959a54c988a20004b4086fbd8
Autor:
Risha Haldar, Amlanjyoti Dhar, Debayan Ganguli, Suparna Chakraborty, Ananda Pal, George Banik, Shin-ichi Miyoshi, Santasabuj Das
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Human Salmonella infections pose significant public health challenges globally, primarily due to low diagnostic yield of systemic infections, emerging and expanding antibiotic resistance of both the typhoidal and non-typhoidal Salmonella strains and
Externí odkaz:
https://doaj.org/article/60eb81b42ab947bc9992ed434712d48a