P39 Better Outcomes and Value for Money with Cost-Effectiveness Modelling of Cascade Screening Strategies for Familial Hypercholesterolaemia

Autor: R Faria, E Cox, P Saramago, K Haralambos, M Watson, SE Humphries, N Qureshi, B Woods

Publikováno v: Value in Health. 25:S9

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::730ddd8a094177c389934a84af47584b
https://doi.org/10.1016/j.jval.2021.11.037

POSC216 How Should Public Health Recommendations Address LP(A), a Causative Risk Factor for Cardiovascular Disease (CVD)?

Autor: AL Catapano, M Daccord, E Damato, SE Humphries, DG Neely, BG Nordestgaard, M Pistollato, E Steinhagen-Thiessen

Publikováno v: Value in Health. 25:S150

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fd20252a72918a763a2f65cf661c92a
https://doi.org/10.1016/j.jval.2021.11.731

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

Autor: Ks, Vimaleswaran, Cavadino A, Dj, Berry, LifeLines Cohort Study investigators, Jorde R, Ak, Dieffenbach, Lu C, Ac, Alves, Hj, Heerspink, Tikkanen E, Eriksson J, Wong A, Mangino M, Ka, Jablonski, Im, Nolte, Dk, Houston, Ts, Ahluwalia, Pj, Most, Pasko D, Zgaga L, Thiering E, Vitart V, Rm, Fraser, Je, Huffman, Ra, Boer, Schöttker B, Ku, Saum, Mi, Mccarthy, Dupuis J, Kh, Herzig, Sebert S, Pouta A, Laitinen J, Me, Kleber, Navis G, Lorentzon M, Jameson K, Arden N, Ja, Cooper, Acharya J, Hardy R, Raitakari O, Ripatti S, Lk, Billings, Lahti J, Osmond C, Bw, Penninx, Rejnmark L, Kk, Lohman, Paternoster L, Rp, Stolk, Dg, Hernandez, Byberg L, Hagström E, Melhus H, Ingelsson E, Mellström D, Ljunggren O, Tzoulaki I, McLachlan S, Theodoratou E, Cm, Tiesler, Jula A, Navarro P, Af, Wright, Polasek O, International Consortium for Blood Pressure (ICBP), Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium, Global Blood Pressure Genetics (Global BPGen) consortium, Caroline Hayward, Jf, Wilson, Rudan I, Salomaa V, Heinrich J, Campbell H, Jf, Price, Karlsson M, Lind L, Michaëlsson K, Bandinelli S, Tm, Frayling, Ca, Hartman, Ti, Sørensen, Sb, Kritchevsky, Bl, Langdahl, Jg, Eriksson, Jc, Florez, Td, Spector, Lehtimäki T, Kuh D, Se, Humphries, Cooper C, Ohlsson C, März W, Mh, Borst, Kumari M, Mika Kivimaki, Tj, Wang, Power C, Brenner H, Grimnes G, van der Harst P, Snieder H, Ad, Hingorani, Pilz S, Jc, Whittaker, Järvelin MR, Hyppönen E

Publikováno v: Europe PubMed Central

BACKGROUND: Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian randomisation approach to test whether 25

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::425db1caf29762d177e8497e030e1999
https://researchonline.lshtm.ac.uk/id/eprint/1878076/1/NIHMS721970-supplement-Supplementary_Appendix.pdf

Identification of a novel (-748G>A) polymorphism in the promoter of the gene for CRP: lack of association with CRP levels in healthy men

Autor: F Zito, SE Humphries, George J. Miller, E Hawe, A Hingorani

Publikováno v: BMC News and views. 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3bae08a9e0bda4a18eca3f2227ed58ca
https://doi.org/10.1186/2048-4623-1-s2-050

Gene-environment interaction in the determination of levels of haemostatic variables involved in thrombosis and fibrinolysis

Autor: Se, Humphries, Ja, Henry, Hugh Montgomery

Publikováno v: Europe PubMed Central

Although a specific genotype may be associated in healthy subjects with modest differences in levels of a risk factor for thrombosis, this effect may be larger or smaller in subgroups of subjects. Documenting such gene-environment interactions is imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a827948fe5475210aecc62f0f13a4c62
https://pubmed.ncbi.nlm.nih.gov/10070812