Zobrazeno 1 - 10
of 962
pro vyhledávání: '"SDHA"'
Autor:
Melakhessou Mohamed Akram, Eddine Marref Salah, Zahra Doumandji, Ramia Safar, Marref Cherine, Imene Becheker, Olivier Joubert
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 37, Iss 3, Pp 138-142 (2024)
Atractylis flava Desf. (AF) is common plant that is widely used for its anti- inflammatory and antioxidant properties. The purpose of this study was, therefore, to evaluate the cytotoxic effect and the molecular basis of antioxidant and anti-inflamma
Externí odkaz:
https://doaj.org/article/94d8f310d369463a938cb66b20b15731
Autor:
Shuiqing Hu, Jinlan Luo, Ping Guo, Tingyi Du, Xiaohui Liu, Miaomiao He, Jie Li, Tingqiong Ma, Bo Liu, Man Huang, Qin Fang, Yan Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115645- (2023)
Diabetic cardiomyopathy (DCM), characterized by mitochondrial dysfunction and impaired energetics as contributing factors, significantly contributes to high mortality in patients with diabetes. Targeting key proteins involved in mitochondrial dysfunc
Externí odkaz:
https://doaj.org/article/8ad5da21c4a94def88273124bcec541c
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18868- (2023)
Background: Copy number variation sequencing (CNV-seq) was proven to be a highly effective tool in studying of chromosomal copy number variations (CNVs) in prenatal diagnosis and post-natal cases with developmental abnormalities. However, the overall
Externí odkaz:
https://doaj.org/article/6c6c00f13af34f30ac2e8086b754e15d
Autor:
Firas M. Abed, Michael J. Dark
Publikováno v:
Iraqi Journal of Veterinary Sciences, Vol 36, Iss Supplement I, Pp 143-150 (2022)
Pheochromocytomas (PCs) are tumors originating from the chromaffin cells of the adrenal medulla. In people, there are highly correlated to inherited gene mutations in the succinate dehydrogenase (SDH) pathway; however, to date, little work has been d
Externí odkaz:
https://doaj.org/article/d11992e84ae541f095c803c78f6685be
Akademický článek
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Autor:
Maria A. Pantaleo, Milena Urbini, Angela Schipani, Margherita Nannini, Valentina Indio, Antonio De Leo, Bruno Vincenzi, Antonella Brunello, Giovanni Grignani, Mariaelena Casagrande, Elena Fumagalli, Elena Conca, Maristella Saponara, Elisa Gruppioni, Annalisa Altimari, Dario De Biase, Giovanni Tallini, Gloria Ravegnini, Daniela Turchetti, Marco Seri, Andrea Ardizzoni, Paola Secchiero, Annalisa Astolfi
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
BackgroundSDH-deficient gastrointestinal stromal tumors (GIST) account for 20–40% of all KIT/PDGFRA-negative GIST and are due to mutations in one of the four SDH-complex subunits, with SDHA mutations as the most frequent. Here we sought to evaluate
Externí odkaz:
https://doaj.org/article/2b333e1899ab413d8278b59ee9ae4ebf
Autor:
Moon Ley Tung, Bharatendu Chandra, Kyle Dillahunt, Matthew D. Gosse, T. Shawn Sato, Alpa Sidhu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Von Hippel Lindau(VHL)syndrome presents with cerebellar and spinal hemangioblastomas, renal cell cancer, neuroendocrine pancreatic tumor, and pheochromocytoma and it is caused by germline mutations in the VHL gene. Pathogenic germline variants in the
Externí odkaz:
https://doaj.org/article/91e24c9475cf4bd48f78f577fcce8848
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Xizan Yue, Bo Liu, Tiantian Han, Ningning Luo, Guanghua Lu, Didi Guo, Fanfeng Bu, Guangyu Wang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Central nervous system germ cell tumors (CNS GCTs) are a heterogeneous group of primary CNS tumors. GCTs are more common and mostly observed in pediatric and young adult patients. CNS GCTs are divided into germinomas and non-germinomatous germ cell t
Externí odkaz:
https://doaj.org/article/89cc838fbad74b2d904f9e3eea13c7b8
Publikováno v:
Genes, Vol 14, Iss 3, p 646 (2023)
Loss of function of the succinate dehydrogenase complex characterizes 20–40% of all KIT/PDGFRA-negative GIST. Approximately half of SDH-deficient GIST patients lack SDHx mutations and are caused by a hypermethylation of the SDHC promoter, which cau
Externí odkaz:
https://doaj.org/article/e09806fb7d324ff3bb4f374eb0d80db9