Zobrazeno 1 - 10
of 41
pro vyhledávání: '"SDH, Succinate dehydrogenase"'
Publikováno v:
Journal of Developmental Biology, Vol 11, Iss 4, p 39 (2023)
Today, agriculture around the world is challenged by parasitic nematode infections. Plant-parasitic nematodes (PPNs) can cause significant damage and crop loss and are a threat to food security. For a long time, the management of PPN infection has re
Externí odkaz:
https://doaj.org/article/a5682e15cdb2419e932dd4bb9fd059c5
Akademický článek
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Autor:
Jie Wang, Krisztian Sebestyen, Kathleen C. Clement, Ana Karen Velez, Jennifer S. Lawton, Joseph K. Canner, Alejandro Suarez-Pierre, Jie Dong, Thaniyyah Ahmad, Michael P. Murphy
Publikováno v:
JTCVS Open. 8:338-354
Background Myocytes exposed to stress exhibit significant swelling and reduced contractility. These consequences are ameliorated by adenosine triphosphate–sensitive potassium (KATP) channel opener diazoxide (DZX) via an unknown mechanism. KATP chan
Autor:
Lu Tian, Wanfang Li, Jinfeng Wei, Zhi Zhou, Yanhua Chen, Zhonghua Wang, Wenqing Fu, Yaqi Liu, Baili Wang, Bingshu He, Meiling Huo, Jianzhen Xia, Zeper Abliz
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 11, Pp 3665-3677 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Detailed knowledge on tissue-specific metabolic reprogramming in diabetic nephropathy (DN) is vital for more accurate understanding the molecular pathological signature and developing novel therapeutic strategies. In the present study, a spatial-reso
Autor:
Niamh C. Williams, Dylan G. Ryan, Ana S.H. Costa, Evanna L. Mills, Mark P. Jedrychowski, Suzanne M. Cloonan, Christian Frezza, Luke A. O'Neill
Publikováno v:
The Journal of Biological Chemistry
Activated macrophages undergo metabolic reprogramming, which not only supports their energetic demands but also allows for the production of specific metabolites that function as signaling molecules. Several Krebs cycles, or Krebs-cycle-derived metab
Publikováno v:
The Journal of Biological Chemistry
Persistent inactivity promotes skeletal muscle atrophy, marked by mitochondrial aberrations that affect strength, mobility, and metabolic health leading to the advancement of disease. Mitochondrial quality control (MQC) pathways include biogenesis (s
Autor:
Hong Soon Kang, Anton M. Jetten, Kevin Gerrish, Amir Aghajanian, Ju Youn Beak, Brian C. Jensen, Seok Jae Hong, Wei Huang, Rishi Deshmukh, Nishi Kadakia
Publikováno v:
The Journal of Biological Chemistry
Preserving optimal mitochondrial function is critical in the heart, which is the most ATP-avid organ in the body. Recently, we showed that global deficiency of the nuclear receptor RORα in the "staggerer" mouse exacerbates angiotensin II-induced car
Autor:
Tatjana Holzer, Jürgen Brinckmann, Kristina Probst, Hauke Clausen-Schaumann, Bent Brachvogel, Janine Altmüller, Janica L. Nolte, Ursula Schlötzer-Schrehardt, Kristina Bubb, Richard Wilson, Attila Aszodi, Lutz Fleischhauer, Marcus Krüger
Publikováno v:
The Journal of Biological Chemistry
Energy metabolism and extracellular matrix function together orchestrate and maintain tissue organization, but crosstalk between these processes is poorly understood. Here, we used single cell RNA-seq (scRNA-seq) analysis to uncover the importance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11edf498bb056660ad221fe72a88fe1
http://edoc.mdc-berlin.de/20941/2/20941suppl.zip
http://edoc.mdc-berlin.de/20941/2/20941suppl.zip
Autor:
Jiancheng Zheng, Yibo Gan, XuTan, Ziwen Wang, Chi Zhang, Aihua Zhang, Huilan Wang, Min Luo, Fengying Liao, Ziyuan Zhou, Chunmeng Shi, Lei Long, Yawei Wang, Yu Wang, Zelin Chen, Peng Luo, Long Chen, Yu Huang, Zeyu Yang, Zhongyong Jiang, Xueru Li, Yunsheng Liu
Publikováno v:
Redox Biology
Redox Biology, Vol 46, Iss, Pp 102082-(2021)
Redox Biology, Vol 46, Iss, Pp 102082-(2021)
Idiopathic pulmonary fibrosis (IPF) is characterized by excessive deposition of extracellular matrix in the lung with fibroblast-to-myofibroblast transition, leading to chronically compromising lung function and death. However, very little is known a
Autor:
Philip B. Smith, Arvind M. Korwar, Ayaan Hossain, Tai Jung Lee, Bradley A. Carlson, Ashley E. Shay, Venkatesha Basrur, Howard M. Salis, K. Sandeep Prabhu, Andrew D. Patterson, Kevin P. Conlon
Publikováno v:
The Journal of Biological Chemistry
Trace element selenium (Se) is incorporated as the 21st amino acid, selenocysteine, into selenoproteins through tRNA[Ser]Sec. Selenoproteins act as gatekeepers of redox homeostasis and modulate immune function to effect anti-inflammation and resoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da3b13128186330a568d97fcebab8ca
https://doi.org/10.1101/2021.01.16.426951
https://doi.org/10.1101/2021.01.16.426951