Proteomic Analysis of Trichomonas vaginalis Phagolysosome, Lysosomal Targeting, and Unconventional Secretion of Cysteine Peptidases

Autor: Nadine, Zimmann, Petr, Rada, Vojtěch, Žárský, Tamara, Smutná, Kristína, Záhonová, Joel, Dacks, Karel, Harant, Ivan, Hrdý, Jan, Tachezy

Publikováno v: Molecular & Cellular Proteomics : MCP

The lysosome represents a central degradative compartment of eukaryote cells, yet little is known about the biogenesis and function of this organelle in parasitic protists. Whereas the mannose 6-phosphate (M6P)-dependent system is dominant for lysoso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d8b7a8dffd0ed0f52289b27ed2884830
https://pubmed.ncbi.nlm.nih.gov/34763061

In-Depth Characterization of the Staphylococcus aureus Phosphoproteome Reveals New Targets of Stk1

Autor: Prust, Nadine, van der Laarse, Saar A M, van den Toorn, Henk, van Sorge, Nina M, Lemeer, Simone, Sub Biomol.Mass Spectrometry & Proteom., Afd Biomol.Mass Spect. and Proteomics, Sub Education Institute Chemistry, Biomolecular Mass Spectrometry and Proteomics

Publikováno v: Molecular & Cellular Proteomics : MCP
Molecular and Cellular Proteomics, 20, 1. American Society for Biochemistry and Molecular Biology Inc.
Molecular and Cellular Proteomics, 20:100034. American Society for Biochemistry and Molecular Biology Inc.

Staphylococcus aureus is a major cause of infections worldwide, and infection results in a variety of diseases. As of no surprise, protein phosphorylation is an important game player in signaling cascades and has been shown to be involved in S. aureu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06efab9f37d80ca60546b1a5b0c7f145
https://doi.org/10.1074/mcp.ra120.002232

Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

Autor: Michael J. Davies, Christine Y. Chuang, Astrid Hammer, Simon Dieterich, Luke F. Gamon, Adelina Rogowska-Wrzesinska, Tina Nybo, Ernst Malle, Gerald Hoefler

Publikováno v: Nybo, T, Dieterich, S, Gamon, L F, Chuang, C Y, Hammer, A, Hoefler, G, Malle, E, Rogowska-Wrzesinska, A & Davies, M J 2019, ' Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase ', Redox Biology, vol. 20, pp. 496-513 . https://doi.org/10.1016/j.redox.2018.10.022
Redox Biology, Vol 20, Iss, Pp 496-513 (2019)
Redox Biology

Basement membranes are specialized extracellular matrices that underlie arterial wall endothelial cells, with laminin being a key structural and biologically-active component. Hypochlorous acid (HOCl), a potent oxidizing and chlorinating agent, is fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbabf82455fc551721050f1ce060d7ec
https://curis.ku.dk/ws/files/229271387/OA_Chlorination_and_oxidation_of_the_extracellular_matrix_protein_laminin.pdf

Comparing the proteome of snap frozen, RNAlater preserved, and formalin-fixed paraffin-embedded human tissue samples

Autor: Tue Bjerg Bennike, Michael Gaihede, Svend Birkelund, Vibeke Andersen, Allan Stensballe, Simona Padurariu, Kenneth Kastaniegaard

Publikováno v: Bennike, T B, Kastaniegaard, K, Padurariu, S, Gaihede, M, Birkelund, S, Andersen, V & Stensballe, A 2016, ' Comparing the proteome of snap frozen, RNAlater preserved, and formalin-fixed paraffin-embedded human tissue samples ', EuPA Open Proteomics, vol. 10, pp. 9-18 . https://doi.org/10.1016/j.euprot.2015.10.001
Bennike, T B, Kastaniegaard, K, Padurariu, S, Gaihede, M, Birkelund, S, Andersen, V & Stensballe, A 2016, ' Comparing the proteome of snap frozen, RNAlater preserved, and formalin-fixed paraffin-embedded human tissue samples ', EuPA Open Proteonomics, vol. 10, pp. 9-18 . https://doi.org/10.1016/j.euprot.2015.10.001
EuPA Open Proteomics
EuPA Open Proteomics, Vol 10, Iss C, Pp 9-18 (2016)

Graphical abstract
Highlights ⿢ We evaluated proteome analyses of snap frozen, RNAlater, and FFPE preserved samples. ⿢ Reliable proteome studies can be conducted on RNAlater, and FFPE preserved samples. ⿢ RNAlater sample preservation is hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e084cbc1a9e833e502789ab6b5f064e
https://vbn.aau.dk/da/publications/c97a5ae4-d8fb-4198-8390-67039db4e6a3

Oral delivery of proteins and peptides: Challenges, status quo and future perspectives.

Autor: Zhu Q; Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China., Chen Z; Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China., Paul PK; Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China.; Department of Pharmacy, Gono Bishwabidyalay (University), Mirzanagar Savar, Dhaka 1344, Bangladesh., Lu Y; Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China.; Key Laboratory of Smart Drug Delivery of MOE, School of Pharmacy, Fudan University, Shanghai 201203, China., Wu W; Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China.; Key Laboratory of Smart Drug Delivery of MOE, School of Pharmacy, Fudan University, Shanghai 201203, China., Qi J; Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China.; Key Laboratory of Smart Drug Delivery of MOE, School of Pharmacy, Fudan University, Shanghai 201203, China.

Publikováno v: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2021 Aug; Vol. 11 (8), pp. 2416-2448. Date of Electronic Publication: 2021 Apr 29.