Zobrazeno 1 - 5
of 5
pro vyhledávání: '"SD Chell"'
Autor:
Moganaden Moorghen, Massimo Pignatelli, Christos Paraskeva, David Qualtrough, Nahida A. Banu, Andrea Buda, Dje Elder, SD Chell
Publikováno v:
Cell Proliferation. 40:768-779
The use of non‐steroidal anti‐inflammatory drugs has proved of great interest in the prevention and treatment of colorectal cancer, although their precise mechanisms of action remain unclear. Overexpression of cyclooxygenase‐2 (COX‐2) and sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35c8d6fa6cc32f25a8cf632f4234a35
https://doi.org/10.1111/j.1365-2184.2007.00459.x
https://doi.org/10.1111/j.1365-2184.2007.00459.x
Autor:
Abderrahmane Kaidi, SD Chell, Henry N. Jabbour, Ann C. Williams, Christos Paraskeva, David Qualtrough
Publikováno v:
International Journal of Cancer. 121:734-740
Colorectal cancer remains a major cause of cancer deaths globally. The inducible form of cyclooxygenase (COX-2), the key enzyme in prostanoid biosynthesis, is overexpressed in over 80% of colorectal cancers.1 Furthermore, COX-2 is frequently expresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f1903fcebfa673c87ee3c03a44c6b0
https://doi.org/10.1002/ijc.22755
https://doi.org/10.1002/ijc.22755
Autor:
M Moorghen, Andrew A. Herman, Ian R. Witherden, Christos Paraskeva, SD Chell, Ann C. Williams, Richard R H Dobson, David Qualtrough
Publikováno v:
Cancer Research. 66:3106-3113
Cyclooxygenase-2 and prostaglandin E2 (PGE2) levels are increased in colorectal cancers and a subset of adenomas. PGE2 signaling through the EP4 receptor has previously been associated with colorectal tumorigenesis. However, changes in EP4 expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed69819b4523c92acb0b50d3aa6ef478
https://doi.org/10.1158/0008-5472.can-05-3702
https://doi.org/10.1158/0008-5472.can-05-3702
Autor:
SD Chell, Ann C. Williams, A-M H-Zadeh, Christos Paraskeva, David Qualtrough, Helena A. Patsos, Diane J. Hicks, IR Witherden, Abderrahmane Kaidi
Publikováno v:
University of Bristol-PURE
There is strong evidence for an important role for increased COX (cyclo-oxygenase)-2 expression and PG (prostaglandin) E2 production in colorectal tumorigenesis. PGE2 acts through four E-prostanoid receptors (EP1–4). COX-2 has therefore become a ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb062e5659516ff565f4b38fcec7c1a
https://pubmed.ncbi.nlm.nih.gov/16042570
https://pubmed.ncbi.nlm.nih.gov/16042570
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1775:341
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2515209f792504d75266f22a769aaa82
https://doi.org/10.1016/j.bbcan.2006.12.001
https://doi.org/10.1016/j.bbcan.2006.12.001