Zobrazeno 1 - 8
of 8
pro vyhledávání: '"SCR, short consensus repeat"'
Autor:
Thierry Tabary, Sandra Audonnet, Jacques H. M. Cohen, Lukshe Kanagaratnam, Firouzé Bani-Sadr, Rachid Mahmoudi, Joël Cousson, Damien Jolly, Nathalie Schneider, Aymric Kisserli, Antoine Goury
Publikováno v:
Immunobiology
Immunobiology, Elsevier, 2021, 226 (3), pp.152093. ⟨10.1016/j.imbio.2021.152093⟩
Immunobiology, 2021, 226 (3), pp.152093. ⟨10.1016/j.imbio.2021.152093⟩
Immunobiology, Elsevier, 2021, 226 (3), pp.152093. ⟨10.1016/j.imbio.2021.152093⟩
Immunobiology, 2021, 226 (3), pp.152093. ⟨10.1016/j.imbio.2021.152093⟩
In order to study the mechanisms of COVID-19 damage following the complement activation phase occurring during the innate immune response to SARS-CoV-2, CR1 (the regulating complement activation factor, CD35, the C3b/C4b receptor), C4d deposits on Er
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18804c6bb85d5082b7961b88d7dcbad0
https://hal.univ-reims.fr/hal-03330724
https://hal.univ-reims.fr/hal-03330724
Autor:
Rolf T. Urbanus, Kim Dijkxhoorn, Karen Silence, Peter Boross, Elisabeth de Zeeuw, Louis Boon, Jan Meeldijk, Christophe Blanchetot, Jeanette H. W. Leusen, Sofie Gabriels, Henny G. Otten, Liesbeth Van de Ven, Kevin Budding, Hans de Haard, Jean-Michel Percier, Rob Holgate, Peter J. Simons, Johanna Wildemann, C. Erik Hack, Inge Van de Walle, Linda J. Cox, Cafer Yildiz
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background Activation of the classical and lectin pathway of complement may contribute to tissue damage and organ dysfunction of antibody-mediated diseases and ischemia-reperfusion conditions. Complement factors are being considered as targets for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fe17fec6eb2a3b3724be8ca3d9a198
https://doi.org/10.1016/j.jaci.2020.08.028
https://doi.org/10.1016/j.jaci.2020.08.028
Autor:
Mitchell J. de Souza, Matthew P. Hardy, Martin J. Pearse, Kim G. Lieu, Saw Yen Ow, Martin O. Spycher, Anup G. Nair, Michael J. Wilson, Jason Simmonds, Yun Dai, Sandra Wymann, Adrian Zuercher, Anna Schnell, Con Panousis, Rebecca E. Butcher, Glenn A. Powers, Marcel Mischnik, Tony Rowe, Genevieve Martin-Roussety, Adriana Baz Morelli, Helen Cao, David Leong, Shirley Taylor
Publikováno v:
The Journal of Biological Chemistry
Human complement receptor 1 (HuCR1) is a pivotal regulator of complement activity, acting on all three complement pathways as a membrane-bound receptor of C3b/C4b, C3/C5 convertase decay accelerator, and cofactor for factor I-mediated cleavage of C3b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605c43f8a6fc70ffcd57fb8866f643b1
https://doi.org/10.1074/jbc.ra120.016127
https://doi.org/10.1074/jbc.ra120.016127
Autor:
Gaojie Song, Jie Yang, Shengzhao Xu, Na Li, Minghui Niu, Deqiang Yao, Jie Yan, Guisheng Zhong
Publikováno v:
The Journal of Biological Chemistry
The adhesion G protein–coupled receptor CD97 and its ligand complement decay-accelerating factor CD55 are important binding partners in the human immune system. Dysfunction in this binding has been linked to immune disorders such as multiple sclero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237396c2f68f577b12d1cf847c83c1ce
https://doi.org/10.1016/j.jbc.2021.100776
https://doi.org/10.1016/j.jbc.2021.100776
Autor:
Yong-Gang, He, Isabel Y, Pappworth, Andreas, Rossbach, Joshua, Paulin, Tarirai, Mavimba, Christine, Hayes, Liudmila, Kulik, V Michael, Holers, Andrew M, Knight, Kevin J, Marchbank
Publikováno v:
Immunobiology
The use of C3d, the final degradation product of complement protein C3, as a “natural” adjuvant has been widely examined since the initial documentation of its immunogenicity-enhancing properties as a consequence of binding to complement receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2165afd706646c50f9d622f90197a0e8
https://pubmed.ncbi.nlm.nih.gov/29017821
https://pubmed.ncbi.nlm.nih.gov/29017821
Publikováno v:
Biochemical Society Transactions
Members within the paramyxovirus subfamily Paramyxovirinae constitute a large number of highly virulent human and animal pathogens. The glycoproteins present on these viruses are responsible for mediating host cell attachment and fusion and are key t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4331a9abcdd5e36609ea3a74e4cf8f34
http://europepmc.org/articles/PMC3433257
http://europepmc.org/articles/PMC3433257
Autor:
Jayne L. Chamberlain-Banoub, Bryan Paul Morgan, Natalie J. Hepburn, Anwen Sian Williams, Claire L. Harris
Publikováno v:
Molecular Immunology
Despite its vital role in innate immunity, complement is involved in a number of inflammatory pathologies and has therefore become a therapeutic target. Most agents generated for anti-complement therapy have short half-lives in plasma, or have been o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63c574336baab19a4a86867dcbe5c82
https://doi.org/10.1016/j.molimm.2007.06.144
https://doi.org/10.1016/j.molimm.2007.06.144
Autor:
Martínez-Barricarte, Rubén, Heurich, Meike, López-Perrote, Andrés, Tortajada, Agustin, Pinto, Sheila, López-Trascasa, Margarita, Sánchez-Corral, Pilar, Morgan, B. Paul, Llorca, Oscar, Harris, Claire L., Rodríguez de Córdoba, Santiago
Publikováno v:
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Molecular Immunology
Consejería de Sanidad de la Comunidad de Madrid
Molecular Immunology
Highlights • Mutations in C3 have been associated with aHUS and other glomerulopathies. • aHUS-associated C3 mutants R592W, R161W, and I1157T impair regulation by MCP, but not by FH. • EM analysis provides the structural basis for the functiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::55295c489a9386cf1427c8a49fe646f9
https://saludmadrid.ibai.com/handle/20.500.12530/22195
https://saludmadrid.ibai.com/handle/20.500.12530/22195