BTN3A3 inhibits the proliferation, migration and invasion of ovarian cancer cells by regulating ERK1/2 phosphorylation

Autor: Sihan Chen, Zhangyun Li, Yanyan Wang, Shaohua Fan

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Butyrophilin Subfamily 3 Member A3 (BTN3A3) is a type I transmembrane protein belonging to the immunoglobulin (Ig) superfamily, which is expressed in many cancers. Clinical data show that ovarian cancer patients with high expression of BTN3A3 have a

Externí odkaz: https://doaj.org/article/ce789a98393d4435b7cd7142340ecd5a

Selective Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibition by the SCH772984 Compound Attenuates In Vitro and In Vivo Inflammatory Responses and Prolongs Survival in Murine Sepsis Models

Autor: Michal Kopczynski, Izabela Rumienczyk, Maria Kulecka, Małgorzata Statkiewicz, Kazimiera Pysniak, Zuzanna Sandowska-Markiewicz, Urszula Wojcik-Trechcinska, Krzysztof Goryca, Karolina Pyziak, Eliza Majewska, Magdalena Masiejczyk, Katarzyna Wojcik-Jaszczynska, Tomasz Rzymski, Karol Bomsztyk, Jerzy Ostrowski, Michal Mikula

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 19, p 10204 (2021)

Sepsis is the leading cause of death in intensive care units worldwide. Current treatments of sepsis are largely supportive and clinical trials using specific pharmacotherapy for sepsis have failed to improve outcomes. Here, we used the lipopolysacch

Externí odkaz: https://doaj.org/article/9b52940364734e1bba72e480f759f9cc

Selective Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibition by the SCH772984 Compound Attenuates In Vitro and In Vivo Inflammatory Responses and Prolongs Survival in Murine Sepsis Models

Autor: Urszula Wojcik-Trechcinska, Krzysztof Goryca, Michal Kopczynski, Kazimiera Pysniak, Jerzy Ostrowski, Katarzyna Wojcik-Jaszczynska, Maria Kulecka, Zuzanna Sandowska-Markiewicz, Izabela Rumienczyk, Eliza Majewska, Malgorzata Statkiewicz, Karolina Pyziak, Magdalena Masiejczyk, Karol Bomsztyk, Michal Mikula, Tomasz Rzymski

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10204, p 10204 (2021)

Sepsis is the leading cause of death in intensive care units worldwide. Current treatments of sepsis are largely supportive and clinical trials using specific pharmacotherapy for sepsis have failed to improve outcomes. Here, we used the lipopolysacch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0e5085548a5f79d46e71d6e01ae785

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