Zobrazeno 1 - 10
of 38
pro vyhledávání: '"SCF, Stem Cell Factor"'
Autor:
Timofey D. Lebedev, Elmira R. Vagapova, Vladimir I. Popenko, Olga G. Leonova, Pavel V. Spirin, Vladimir S. Prassolov
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Pediatric cancers represent a wide variety of different tumors, though they have unique features that distinguish them from adult cancers. Receptor tyrosine kinases KIT and TrkA functions in AML and NB, respectively, are well-characterized. Though ex
Externí odkaz:
https://doaj.org/article/0957f75265314e659be1679666207c8c
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 843-856 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
The epithelial lining of the intestine, particularly the stem cell compartment, is affected by harsh conditions in the luminal environment and also is susceptible to genotoxic agents such as radiation and chemotherapy. Therefore, the ability for inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2c4548990c68ba5ebf409224d926be
http://www.sciencedirect.com/science/article/pii/S2352345X21002551
http://www.sciencedirect.com/science/article/pii/S2352345X21002551
Autor:
Brian J. Nickoloff, Silvia Ottaviani, Jonathan T. Sims, Nicoletta Bivi, Richard E. Higgs, Ajay Nirula, Venkatesh Krishnan, George H. Rodgers, Giacomo Casalini, Robert J. Benschop, Anabela Cardoso, Justin Stebbing, Mario Corbellino, Sarah M. Engle, Ching Yun Chang, Robert J. Konrad, Stephanie de Bono
Publikováno v:
The Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology
Background Physicians treating COVID-19 patients increasingly believe that the hyperinflammatory acute stage of COVID-19 results in a cytokine storm. The circulating biomarkers seen across the spectrum of COVID-19 have not been characterized compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09fd77bcd0ea3c8be3c284be2af4e39
https://doi.org/10.1016/j.jaci.2020.08.031
https://doi.org/10.1016/j.jaci.2020.08.031
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1239-1250 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Paneth cells are professional secretory cells that, classically, play a role in the innate immune system by secreting antimicrobial factors into the lumen to control enteric bacteria. In this role, Paneth cells are able to sense ques from luminal bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6531f8620d6d5bb7bab42db8c576444c
http://www.sciencedirect.com/science/article/pii/S2352345X21001211
http://www.sciencedirect.com/science/article/pii/S2352345X21001211
Publikováno v:
Advanced Drug Delivery Reviews
Graphical abstract
Gene therapy has been widely investigated for the treatment of genetic, acquired, and infectious diseases. Pioneering work utilized viral vectors; however, these are suspected of causing serious adverse events, resulting in th
Gene therapy has been widely investigated for the treatment of genetic, acquired, and infectious diseases. Pioneering work utilized viral vectors; however, these are suspected of causing serious adverse events, resulting in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7413733ccbe4eda7411005d2c1ea69
http://europepmc.org/articles/PMC8518240
http://europepmc.org/articles/PMC8518240
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 5, Pp 469-481 (2019)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Leukemogenic potential of MLL fusion with the coiled-coil domain-containing partner genes and the downstream target genes of this type of MLL fusion have not been clearly investigated. In this study, we demonstrated that the coiled-coil–four-helix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae6e39f4ce6499022a02bece2ea557b
http://www.sciencedirect.com/science/article/pii/S1476558619300090
http://www.sciencedirect.com/science/article/pii/S1476558619300090
Autor:
Yuting Li, Junxiang Ji, Meng Zhang, Qian Ban, Xinbao Zhang, Xiaoxiao Wang, Yan Zhang, Shou-Dong Ye, Xiaofeng Li, Xin Wang
Publikováno v:
The Journal of Biological Chemistry
Primordial germ cells (PGCs) are common ancestors of all germline cells. However, mechanistic understanding of how PGC specification occurs is limited. Here, we identified transcription factor CP2-like 1 (Tfcp2l1), an important pluripotency factor, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44acb44a05e35b6e07993ad30720ada1
https://pubmed.ncbi.nlm.nih.gov/34555410
https://pubmed.ncbi.nlm.nih.gov/34555410
Autor:
Fabiana Muccillo, Vanessa Estato, Hugo C. Castro-Faria-Neto, Andrea De Lorenzo, Leticia R Sabioni, Eduardo Tibiriçá, Cristiane da Cruz Lamas
Publikováno v:
Microvascular Research
Background Microvascular dysfunction, serum cytokines and chemokines may play important roles in pathophysiology of coronavirus disease 2019 (COVID-19), especially in severe cases. Methods Patients with COVID-19 underwent non-invasive evaluation of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608771264121af91a8fb442033f85b15
Autor:
Marco A. Ramos, Ruth Heidelberger, Roberto J. Alcazar-Felix, Roberto Adachi, Eduardo I. Cardenas, Alan R. Burns, Alejandro I. Rodarte, Ricardo Treviño González, Rodolfo A. Cardenas, Alejandro Isaza, Elizabeth Sanchez
Publikováno v:
The Journal of Biological Chemistry
Degranulation, a fundamental effector response from mast cells (MCs) and platelets, is an example of regulated exocytosis. This process is mediated by SNARE proteins and their regulators. We have previously shown that several of these proteins are es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8204093fa71125dcdeede86da55ba3ae
http://europepmc.org/articles/PMC7948755
http://europepmc.org/articles/PMC7948755
Autor:
Pavol Utekal, Lucie Potuckova, Lubica Dráberová, Tomas Paulenda, Michal Mrkacek, Ivana Halova, Ondrej Kuda, Monika Bambouskova, Petr Dráber, Petra Vavrova, Björn Schuster, Daniel Smrz, Viktor Bugajev, Sara Cernohouzova, Sergio Fuentes-Liso, Ladislav Kuchar
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100121-(2021)
Journal of Lipid Research
Journal of Lipid Research
Leukotrienes (LTs) and sphingolipids are critical lipid mediators participating in numerous cellular signal transduction events and developing various disorders, such as bronchial hyperactivity leading to asthma. Enzymatic reactions initiating produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fea2d851867070803df7a1bedbe8cb1
http://www.sciencedirect.com/science/article/pii/S0022227521001036
http://www.sciencedirect.com/science/article/pii/S0022227521001036