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Autor:
SC Stanford
Publikováno v:
British Journal of Pharmacology. 175:3187-3189
LINKED ARTICLES This article is part of a themed section on Recent Developments in Research of Melatonin and its Potential Therapeutic Applications. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v175.
Autor:
SC Stanford
Publikováno v:
Journal of Psychopharmacology. 31:641-643
Preclinical (predictive) screens for psychotropic drugs are often used, incorrectly, as animal ‘models’ of psychiatric disorders, or to study ‘disorder-like’ behaviours. This misunderstanding is contributing to poor translation and is undermi
Autor:
Stephen P. Hunt, Anita Thapar, Hugh Gurling, Philip Asherson, SC Stanford, Andrew McQuillin, TC Yan
Publikováno v:
Journal of Psychopharmacology (Oxford, England)
Mice with functional genetic ablation of the Tacr1 (substance P-preferring receptor) gene (NK1R−/−) are hyperactive. Here, we investigated whether this is mimicked by NK1R antagonism and whether dopaminergic transmission is disrupted in brain reg
Autor:
Kaba, Vanita, Patil, Rajendra R.
Publikováno v:
Indonesian Journal of Electrical Engineering & Computer Science; Apr2024, Vol. 34 Issue 1, p350-361, 12p
Publikováno v:
Scopus-Elsevier
OBJECTIVE Because cardiac transplantation entails neuronal decentralization, cardiac responses to a psychological stressor in transplant patients would be expected to rely on circulating hormonal factors and therefore to be delayed and prolonged. We
Autor:
C.A. Marsden, SC Stanford
Publikováno v:
Expert Opinion on Investigational Drugs. 9:1923-1929
This two-day symposium reviewed specific aspects of current drug development for psychiatric disorders. The aim was to identify how existing drugs could he improved and what approaches could he adopted to develop new drugs acting by different mechani
Autor:
R McQuade, SC Stanford
Publikováno v:
Psychopharmacology. 148:201-208
Rationale: Extracellular noradrenaline concentration in the rat forebrain is increased by aversive environmental stimuli. This study investigated whether conditioned cues for such stimuli have the same effect. Methods: After training rats to associat
Publikováno v:
British Journal of Pharmacology. 128:659-666
1. The effects of sibutramine (0.25 - 10 mg kg-1 i.p.) on extracellular noradrenaline concentration in the frontal cortex and hypothalamus of freely-moving rats were investigated using microdialysis. The role of presynaptic alpha2-adrenoceptors in mo