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pro vyhledávání: '"SB-269970"'
Akademický článek
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Publikováno v:
Neurological Research. 44:786-796
Objectives: Recently, studies have demonstrated that serotonin type 7 receptors (5-HT7) have conflincting effects on neuronal excitability in different brain regions. However, the effect of 5-HT7 on seizures has not been exactly elucidated yet. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9107fd4caa0b921b3f530d6022540b29
https://doi.org/10.1080/01616412.2022.2064700
https://doi.org/10.1080/01616412.2022.2064700
Publikováno v:
ACS Chem Neurosci
5-HT7 receptor antagonism has been shown to ameliorate ketamine-induced schizophrenia-like deficits in extradimensional set-shifting using the attentional set-shifting task (ASST). However, this rodent paradigm distinguishes between several types of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37aa85ade9fcaac28e1ffde41291a84d
https://doi.org/10.1021/acschemneuro.0c00554
https://doi.org/10.1021/acschemneuro.0c00554
Autor:
Joanna Sowa, Grzegorz Hess
Publikováno v:
European Journal of Neuroscience. 52:3295-3305
Early life adversity exerts a detrimental influence on developing brain neuronal networks and its consequences may include mental health disorders. In rats, prenatal stress may lead to anxiety and depressive-like behavior in the offspring. Several li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a864153bfef640a6fb386cac500085e9
https://doi.org/10.1111/ejn.14778
https://doi.org/10.1111/ejn.14778
Autor:
Kjell A. Svensson, Julia K. Maxwell, Julie F. Falcone, Scott D. Gleason, Jeffrey M. Witkin, Olivia M. Balcer, Xia Li
Publikováno v:
Behavioural Brain Research. 359:467-473
5-HT7 receptors have been suggested to play a role in the regulation of psychiatric disorders. The experimental literature however is not fully consistent on this possibility. Two selective 5-HT7 receptor antagonists, DR-4004 and SB-269970, were eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e386aa16fb99357fc46ba42589abdbc6
https://doi.org/10.1016/j.bbr.2018.11.019
https://doi.org/10.1016/j.bbr.2018.11.019
Autor:
Thiago Roberto Lima Romero, Igor D.G. Duarte, Márcio M. Coelho, Marcela M.G.B. Dutra, Bernd L. Fiebich, Elias B. Nascimento
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 135, Iss, Pp 111210-(2021)
Serotonin (5-HT) acts as a neurotransmitter in the central nervous system (CNS) and as a mediator released by enterochromaffin cells to regulate intestinal motility. However, this amine also plays an important role as an inflammatory mediator and ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee725fd10aeea9ffdd29c2240fd7d965
http://www.sciencedirect.com/science/article/pii/S0753332220314037
http://www.sciencedirect.com/science/article/pii/S0753332220314037
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Joanna Sowa, J.E. Sowa, Grzegorz Hess, Magdalena Kusek, Bartosz Bobula, Krzysztof Tokarski, Marcin Siwiec
Publikováno v:
Psychopharmacology. 235:3381-3390
Chronic stress and corticosterone have been shown to affect serotonin (5-HT) neurotransmission; however, the influence of stress on the activity of the dorsal raphe nucleus (DRN), the main source of 5-HT in the forebrain, is not well understood. In p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::215c4e067f8a9b4e266030ebf078fc5d
https://doi.org/10.1007/s00213-018-5045-y
https://doi.org/10.1007/s00213-018-5045-y
Publikováno v:
Psychopharmacology. 235:2795-2808
The effect of atypical antipsychotic drugs (AAPDs), e.g., lurasidone, to improve cognitive impairment associated with schizophrenia (CIAS), has been suggested to be due, in part, to enhancing release of dopamine (DA), acetylcholine (ACh), and glutama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f595727941eb2988bb33c64730917bf
https://doi.org/10.1007/s00213-018-4972-y
https://doi.org/10.1007/s00213-018-4972-y