Zobrazeno 1 - 10
of 413
pro vyhledávání: '"SATOSHI SAKAGUCHI"'
Autor:
Naoki Okamoto, Kenta Yagi, Sayaka Imawaka, Mayu Takaoka, Fuka Aizawa, Takahiro Niimura, Mitsuhiro Goda, Koji Miyata, Kei Kawada, Yuki Izawa‐Ishizawa, Satoshi Sakaguchi, Keisuke Ishizawa
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract In the treatment of chronic myeloid leukemia (CML), resistance to BCR‐ABL inhibitors makes it difficult to continue treatment and is directly related to life expectancy. Therefore, asciminib was introduced to the market as a useful drug fo
Externí odkaz:
https://doaj.org/article/eef81c91c9db4fafb2a4727bbd78f2ae
Autor:
Satoshi Sakaguchi, Shogo Matsuo
Publikováno v:
Molbank, Vol 2024, Iss 2, p M1810 (2024)
Commercially available and air- and moisture-stable rhodium complex [Rh(OH)(cod)]2 (2) was utilized in the synthesis of [RhX(cod)(NHC)] (3). The presence of an OH group in complex 2 serves as an internal base, facilitating the deprotonation of the C
Externí odkaz:
https://doaj.org/article/0fc4c8527e6c424ea4c41c8af1b076ee
Autor:
Satoshi Sakaguchi, Shogo Matsuo
Publikováno v:
Molbank, Vol 2024, Iss 2, p M1811 (2024)
Previously, we demonstrated the synthesis of a well-defined hydroxyalkyl-functionalized N-heterocyclic carbene (NHC)/Ru(II) complex through the transmetalation reaction between [RuCl2(p-cymene)]2 and the corresponding NHC/Ag(I) complex derived from a
Externí odkaz:
https://doaj.org/article/17aba8aafee4400fb1a8c9ae24b33e50
Autor:
Shotaro Haji, Koji Fujita, Ryosuke Oki, Yusuke Osaki, Ryosuke Miyamoto, Hiroyuki Morino, Seiichi Nagano, Naoki Atsuta, Yuki Kanazawa, Yuki Matsumoto, Atsuko Arisawa, Hisashi Kawai, Yasutaka Sato, Satoshi Sakaguchi, Kenta Yagi, Tatsuto Hamatani, Tatsuo Kagimura, Hiroaki Yanagawa, Hideki Mochizuki, Manabu Doyu, Gen Sobue, Masafumi Harada, Yuishin Izumi
Publikováno v:
JMIR Research Protocols, Vol 12, p e42032 (2023)
BackgroundAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder, with its currently approved drugs, including riluzole and edaravone, showing limited therapeutic effects. Therefore, safe and effective drugs are urgently necessary.
Externí odkaz:
https://doaj.org/article/5bcf8cf20c5741ca83d7aded83f2f34c
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100364- (2022)
Asymmetric silane reduction of ketones catalyzed by a system comprising a chiral azolium salt 1 and [Ir(cod)2]BF4 (2) in the presence of a base in methanol was achieved at room temperature within 2 h. Implementing a “pre-mixing” experimental proc
Externí odkaz:
https://doaj.org/article/0fd2ae2b38d24fe3bab6c96356f96eb6
Publikováno v:
Molecules, Vol 26, Iss 11, p 3404 (2021)
Hydroxyamide-functionalized azolium salt (NHC•HI 4) was evaluated for dual enantioselective control in a Cu-catalyzed asymmetric conjugate addition (ACA) reaction. This investigation was based on our previously reported ACA reaction catalyzed using
Externí odkaz:
https://doaj.org/article/04cb0e66c1134a3e9e1ddaf4a9ef7076
Autor:
Mayo Kondo, Hirokazu Ogino, Hirohisa Ogawa, Tania Afroj, Yuko Toyoda, Satoshi Sakaguchi, Miki Tsuboi, Yoshimi Bando, Hisatsugu Goto, Koichi Tsuneyama, Yasuhiko Nishioka
Publikováno v:
Respiratory Medicine Case Reports, Vol 25, Iss , Pp 119-121 (2018)
A 60-year-old man was admitted to our hospital with non-small cell lung cancer (NSCLC). Imaging and pathological studies revealed NSCLC, not otherwise specified (NOS), at clinical stage T3N1M0 stage IIIA. We started radiotherapy alone because of obst
Externí odkaz:
https://doaj.org/article/805048f595304353a82a122880da161d
Publikováno v:
Catalysts, Vol 9, Iss 9, p 780 (2019)
Bis(NHC) ligand precursors, L1, based on trans-1,2-diaminocyclohexane were designed and synthesized. To introduce chirality at the hydroxyamide side arm on the NHC of L1, a chiral β-amino alcohol, such as enantiopure leucinol, was used. Cu-catalyzed
Externí odkaz:
https://doaj.org/article/deb85ec8c8e04c75b6bdb5f6379d62f8
Autor:
Satoshi Sakaguchi, Ichiki Sato, Hiroaki Muguruma, Hiroaki Kawano, Yoshito Kusuhara, Seiji Yano, Saburo Sone, Tsuneo Uchiyama
Publikováno v:
Emerging Infectious Diseases, Vol 10, Iss 5, Pp 964-965 (2004)
Externí odkaz:
https://doaj.org/article/dc44e0633aa44d5b8825fa449ae9d760
Autor:
Kosuke Morita, Satoshi Sakaguchi
Publikováno v:
Journal of the Atomic Energy Society of Japan. 65:45-49