Zobrazeno 1 - 10
of 487
pro vyhledávání: '"SATOSHI SAKAGUCHI"'
Autor:
Naoki Okamoto, Kenta Yagi, Sayaka Imawaka, Mayu Takaoka, Fuka Aizawa, Takahiro Niimura, Mitsuhiro Goda, Koji Miyata, Kei Kawada, Yuki Izawa‐Ishizawa, Satoshi Sakaguchi, Keisuke Ishizawa
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract In the treatment of chronic myeloid leukemia (CML), resistance to BCR‐ABL inhibitors makes it difficult to continue treatment and is directly related to life expectancy. Therefore, asciminib was introduced to the market as a useful drug fo
Externí odkaz:
https://doaj.org/article/eef81c91c9db4fafb2a4727bbd78f2ae
Autor:
Satoshi Sakaguchi, Shogo Matsuo
Publikováno v:
Molbank, Vol 2024, Iss 2, p M1810 (2024)
Commercially available and air- and moisture-stable rhodium complex [Rh(OH)(cod)]2 (2) was utilized in the synthesis of [RhX(cod)(NHC)] (3). The presence of an OH group in complex 2 serves as an internal base, facilitating the deprotonation of the C
Externí odkaz:
https://doaj.org/article/0fc4c8527e6c424ea4c41c8af1b076ee
Autor:
Satoshi Sakaguchi, Shogo Matsuo
Publikováno v:
Molbank, Vol 2024, Iss 2, p M1811 (2024)
Previously, we demonstrated the synthesis of a well-defined hydroxyalkyl-functionalized N-heterocyclic carbene (NHC)/Ru(II) complex through the transmetalation reaction between [RuCl2(p-cymene)]2 and the corresponding NHC/Ag(I) complex derived from a
Externí odkaz:
https://doaj.org/article/17aba8aafee4400fb1a8c9ae24b33e50
Autor:
Shotaro Haji, Koji Fujita, Ryosuke Oki, Yusuke Osaki, Ryosuke Miyamoto, Hiroyuki Morino, Seiichi Nagano, Naoki Atsuta, Yuki Kanazawa, Yuki Matsumoto, Atsuko Arisawa, Hisashi Kawai, Yasutaka Sato, Satoshi Sakaguchi, Kenta Yagi, Tatsuto Hamatani, Tatsuo Kagimura, Hiroaki Yanagawa, Hideki Mochizuki, Manabu Doyu, Gen Sobue, Masafumi Harada, Yuishin Izumi
Publikováno v:
JMIR Research Protocols, Vol 12, p e42032 (2023)
BackgroundAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder, with its currently approved drugs, including riluzole and edaravone, showing limited therapeutic effects. Therefore, safe and effective drugs are urgently necessary.
Externí odkaz:
https://doaj.org/article/5bcf8cf20c5741ca83d7aded83f2f34c
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100364- (2022)
Asymmetric silane reduction of ketones catalyzed by a system comprising a chiral azolium salt 1 and [Ir(cod)2]BF4 (2) in the presence of a base in methanol was achieved at room temperature within 2 h. Implementing a “pre-mixing” experimental proc
Externí odkaz:
https://doaj.org/article/0fd2ae2b38d24fe3bab6c96356f96eb6
Autor:
Kosuke Morita, Satoshi Sakaguchi
Publikováno v:
Journal of the Atomic Energy Society of Japan. 65:45-49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84dc976b8f45060d67fb67ae79dd9fab
https://doi.org/10.3327/jaesjb.65.1_45
https://doi.org/10.3327/jaesjb.65.1_45
Autor:
Rie Ando‐Matsuoka, Kenta Yagi, Mayu Takaoka, Yuko Sakajiri, Tomokazu Shibata, Ryusuke Sawada, Akinori Maruo, Koji Miyata, Fuka Aizawa, Hirofumi Hamano, Takahiro Niimura, Yuki Izawa‐Ishizawa, Mitsuhiro Goda, Satoshi Sakaguchi, Yoshito Zamami, Yoshihiro Yamanishi, Keisuke Ishizawa
Publikováno v:
Drug Development Research. 84:75-83
Proton pump inhibitors (PPIs) are potent inhibitors of gastric acid secretion, used as first-line agents in treating peptic ulcers. However, we have previously reported that PPIs may diminish the therapeutic effect of anti-vascular endothelial growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80bbf28af82f0d0e74f451512a831c1d
https://doi.org/10.1002/ddr.22013
https://doi.org/10.1002/ddr.22013
Publikováno v:
Molecules, Vol 26, Iss 11, p 3404 (2021)
Hydroxyamide-functionalized azolium salt (NHC•HI 4) was evaluated for dual enantioselective control in a Cu-catalyzed asymmetric conjugate addition (ACA) reaction. This investigation was based on our previously reported ACA reaction catalyzed using
Externí odkaz:
https://doaj.org/article/04cb0e66c1134a3e9e1ddaf4a9ef7076
Autor:
Mayo Kondo, Hirokazu Ogino, Hirohisa Ogawa, Tania Afroj, Yuko Toyoda, Satoshi Sakaguchi, Miki Tsuboi, Yoshimi Bando, Hisatsugu Goto, Koichi Tsuneyama, Yasuhiko Nishioka
Publikováno v:
Respiratory Medicine Case Reports, Vol 25, Iss , Pp 119-121 (2018)
A 60-year-old man was admitted to our hospital with non-small cell lung cancer (NSCLC). Imaging and pathological studies revealed NSCLC, not otherwise specified (NOS), at clinical stage T3N1M0 stage IIIA. We started radiotherapy alone because of obst
Externí odkaz:
https://doaj.org/article/805048f595304353a82a122880da161d
Autor:
Hisatsugu Goto, Kozo Kagawa, Makoto Tobiume, Daisuke Matsumoto, Hiroshi Nokihara, Yoshimi Bando, Atsuro Saijo, Hiromitsu Takizawa, Yuriko Morikawa, Hiroshi Kawano, Yasuhiko Nishioka, Hirokazu Ogino, Satoshi Sakaguchi
Publikováno v:
Internal Medicine. 61:1393-1397
A 67-year-old man was admitted to our hospital for massive pleural effusion. He had a history of mandibular gingival carcinoma treated with radiation therapy (RT). Based on the cytology findings of pleural effusion and a thoracoscopic pleural biopsy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da22dcff93f6018e17d046e2c2dfa94
https://doi.org/10.2169/internalmedicine.8195-21
https://doi.org/10.2169/internalmedicine.8195-21