Zobrazeno 1 - 10
of 299
pro vyhledávání: '"SATOSHI MATSUSAKA"'
Autor:
Kazuto Sugai, Tomoko Mori, Turan Bilal, Atsuko Furukawa, Yasuharu Sekine, Naohiro Kobayashi, Shinji Kikuchi, Yukinobu Goto, Hideo Ichimura, Taisuke Masuda, Fumihito Arai, Yukio Sato, Satoshi Matsusaka
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background We developed a Rare Cell Sorter (RCS) for collecting single cell including circulating tumor cells (CTCs). This single-institution pilot study evaluated the ability of this device to detect tumor-like cells in patients with lung c
Externí odkaz:
https://doaj.org/article/06c0418840ef4843b693eb8ff3a3dad4
Autor:
Ibrahim Abd El-Sadek, Rion Morishita, Tomoko Mori, Shuichi Makita, Pradipta Mukherjee, Satoshi Matsusaka, Yoshiaki Yasuno
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract We demonstrate label-free dynamic optical coherence tomography (D-OCT)-based visualization and quantitative assessment of patterns of tumor spheroid response to three anti-cancer drugs. The study involved treating human breast adenocarcinoma
Externí odkaz:
https://doaj.org/article/c69378ac162a44078e5ac59149caf1c9
Autor:
Ibrahim Abd El-Sadek, Larina Tzu-Wei Shen, Tomoko Mori, Shuichi Makita, Pradipta Mukherjee, Antonia Lichtenegger, Satoshi Matsusaka, Yoshiaki Yasuno
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract This study aims at demonstrating label-free drug-response-patterns assessment of different tumor spheroids and drug types by dynamic optical coherence tomography (D-OCT). The study involved human breast cancer (MCF-7) and colon cancer (HT-29
Externí odkaz:
https://doaj.org/article/0a556fd5383e453a97db85576e2b0e7d
Autor:
Antonia Lichtenegger, Junya Tamaoki, Roxane Licandro, Tomoko Mori, Pradipta Mukherjee, Lixuan Bian, Lisa Greutter, Shuichi Makita, Adelheid Wöhrer, Satoshi Matsusaka, Makoto Kobayashi, Bernhard Baumann, Yoshiaki Yasuno
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Breast cancer is a leading cause of death in female patients worldwide. Further research is needed to get a deeper insight into the mechanisms involved in the development of this devastating disease and to find new therapy strategies. The ze
Externí odkaz:
https://doaj.org/article/b4924759e44b4c3a86ab4ddb97d7cfdf
Autor:
Nao Nitta, Takanori Iino, Akihiro Isozaki, Mai Yamagishi, Yasutaka Kitahama, Shinya Sakuma, Yuta Suzuki, Hiroshi Tezuka, Minoru Oikawa, Fumihito Arai, Takuya Asai, Dinghuan Deng, Hideya Fukuzawa, Misa Hase, Tomohisa Hasunuma, Takeshi Hayakawa, Kei Hiraki, Kotaro Hiramatsu, Yu Hoshino, Mary Inaba, Yuki Inoue, Takuro Ito, Masataka Kajikawa, Hiroshi Karakawa, Yusuke Kasai, Yuichi Kato, Hirofumi Kobayashi, Cheng Lei, Satoshi Matsusaka, Hideharu Mikami, Atsuhiro Nakagawa, Keiji Numata, Tadataka Ota, Takeichiro Sekiya, Kiyotaka Shiba, Yoshitaka Shirasaki, Nobutake Suzuki, Shunji Tanaka, Shunnosuke Ueno, Hiroshi Watarai, Takashi Yamano, Masayuki Yazawa, Yusuke Yonamine, Dino Di Carlo, Yoichiroh Hosokawa, Sotaro Uemura, Takeaki Sugimura, Yasuyuki Ozeki, Keisuke Goda
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Most current cell sorting methods are based on fluorescence detection with no imaging capability. Here the authors generate and use Raman image-activated cell sorting with a throughput of around 100 events per second, providing molecular images with
Externí odkaz:
https://doaj.org/article/02b0d5e6a65b4b81bf87a4cb06c904e6
Autor:
Hideharu Mikami, Makoto Kawaguchi, Chun-Jung Huang, Hiroki Matsumura, Takeaki Sugimura, Kangrui Huang, Cheng Lei, Shunnosuke Ueno, Taichi Miura, Takuro Ito, Kazumichi Nagasawa, Takanori Maeno, Hiroshi Watarai, Mai Yamagishi, Sotaro Uemura, Shinsuke Ohnuki, Yoshikazu Ohya, Hiromi Kurokawa, Satoshi Matsusaka, Chia-Wei Sun, Yasuyuki Ozeki, Keisuke Goda
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
High throughput imaging flow cytometry suffers from trade-offs between throughput, sensitivity and spatial resolution. Here the authors introduce a method to virtually freeze cells in the image acquisition window to enable 1000 times longer signal in
Externí odkaz:
https://doaj.org/article/970eb547b4534e9b8248827dc2f21c9b
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2483 (2022)
The antitumor effect of antibody-drug conjugates (ADC) is the main factor in achieving cures. Although the mechanism of tumor resistance to treatment is multifaceted, tumor-derived extracellular vesicles (T-EVs) have been implicated as contributing t
Externí odkaz:
https://doaj.org/article/f93e56eafc46431a802e0087d8d6b4b5
Autor:
Yuji Miyamoto, Marta Schirripa, Mitsukuni Suenaga, Shu Cao, Wu Zhang, Satoshi Okazaki, Martin D Berger, Satoshi Matsusaka, Dongyun Yang, Yan Ning, Hideo Baba, Fotios Loupakis, Sara Lonardi, Filippo Pietrantonio, Beatrice Borelli, Chiara Cremolini, Toshiharu Yamaguchi, Heinz-Josef Lenz
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239439 (2020)
Activin/myostatin signaling has a critical role not only in cachexia but also in tumor angiogenesis. Cachexia is a frequent complication among patients with advanced cancer and heavily pretreated patients. We aimed to evaluate the prognostic signific
Externí odkaz:
https://doaj.org/article/baae7085fd3248ec9c83507338f3ccac
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 4, Pp 364-372 (2005)
The purpose of this study was to investigate the effects of daunorubicin on lipopolysaccharide (LPS)-stimulated inducible-type nitric oxide synthase (iNOS) expression in macrophages. LPS-stimulated iNOS expression and NO production were significantly
Externí odkaz:
https://doaj.org/article/7305844a198d4f8d915ebc4d30b12696
Autor:
Hiroki Matsumura, Larina Tzu-Wei Shen, Akihiro Isozaki, Hideharu Mikami, Dan Yuan, Taichi Miura, Yuto Kondo, Tomoko Mori, Yoshika Kusumoto, Masako Nishikawa, Atsushi Yasumoto, Aya Ueda, Hiroko Bando, Hisato Hara, Yuhong Liu, Yunjie Deng, Masahiro Sonoshita, Yutaka Yatomi, Keisuke Goda, Satoshi Matsusaka
Publikováno v:
Lab on a Chip. 23:1561-1575
Heterogeneous clusters of cancer cells and leukocytes in blood were visualized by combining high-throughput and high-sensitivity fluorescence imaging flow cytometry with 5-aminolevulinic acid stimulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e796de464b35e3941d69b388a19e15ae
https://doi.org/10.1039/d2lc00856d
https://doi.org/10.1039/d2lc00856d